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City of Hope

Research Associate II

City of Hope, Butler, California, United States

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Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life‑threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting‑edge research.

A Research Associate II position is available in the laboratory of Dr. Melanie Shapiro, PhD, in the AR‑DMRI Department of Diabetes Immunology. You will perform a variety of experiments related to the genetics and immunology of type 1 diabetes. The Shapiro laboratory currently studies germline genetic variants predicting response to immunotherapies for type 1 diabetes as well as somatic variants in the pancreas and immune cells of organ donors with type 1 diabetes.

For more information on the Shapiro Laboratory please visit here: https://mshapirolab.academicwebsite.com/

For more information on the Arthur Riggs Diabetes & Metabolism Research Institute please visit here: https://www.cityofhope.org/research/riggs-institute/diabetes-milestones-and-history

Responsibilities

Isolate and culture immune cells in vivo

Perform CRISPR/Cas9‑mediated gene editing

Run multicolor flow cytometry and analysis

Execute ELISA and/or multiplex cytokine quantification assays

Analyze single nucleotide polymorphism genotyping data

Perform murine injections, dissection, and processing of pancreas and immune organs for in vivo experiments

Process and analyze single cell RNA sequencing data

Qualifications

Bachelor's degree. Master’s degree preferred

2+ years of related research/laboratory experience with a Bachelor's degree or 1+ year related research/laboratory experience with a Master’s degree

Some experience in the experimental and analytical techniques listed above is preferred, but not required

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

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