Baylor College of Medicine
Research Associate - Electrophysiology
Baylor College of Medicine, Houston, Texas, United States, 77246
Job Title: Research Associate - Electrophysiology
Work Arrangement: Onsite only
Location: Houston, TX
Salary Range: $65,000 - $72,000
FLSA Status: Exempt
Work Schedule: Monday – Friday, 8 a.m. – 5 p.m.
Summary
The St-Pierre lab develops and applies new tools for monitoring and interrogating brain activity with millisecond-timescale temporal resolution. We seek an energetic team member to lead our efforts to characterize and apply new light-responsive proteins in vitro and in vivo. The Research Associate will work on two types of tools: (1) genetically encoded voltage indicators (GEVIs), fluorescent biosensors that report voltage as changes in brightness, and (2) optogenetic silencers, light-gated channels that inhibit neuronal firing. Characterization of these tools requires simultaneous electrophysiological recordings and optical excitation/imaging. This position provides exciting opportunities to work with the latest optical technologies and develop new skills in two-photon voltage imaging, protein engineering, and synthetic biology. Job Duties
Prepare brain slices, dissociated neurons, or both Conduct experiments that combine electrophysiology and either optogenetic activation or optical imaging (multi-photon fluorescence microscopy) Maintain reagent and tool supply related to the experiments Maintain an electrophysiological rig, and troubleshooting if needed Analyze data using commercial software or customized data pipelines Teach techniques, procedures, and experimental design to other members of the lab Communicate research results in group meetings, national or international conferences Perform other job related duties as assigned Minimum Qualifications
Master's degree in Basic Science or a related field. Experience in lieu of degree will not be accepted. Three years of relevant experience typically as a Research Assistant, Research Technician or Postdoctoral Fellow/Associate. Department Specific Criteria
Must have experience with performingelectrophysiology indissociated neurons, brain slices or both Must have experience with dissecting rat cortical, hippocampal neurons, or both Must have experience maintaining an electrophysiology rig Preferred Qualifications
Ability to express transgenes in neurons of brain slices using viruses and/or in utero electroporation Experience with imaging neural activity (e.g. voltage or calcium) in brain slices or in vivo, using 1P and/or 2P imaging Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer. Baylor College of Medicine fosters diversity among its students, trainees, faculty, and staff as a prerequisite to accomplishing our institutional mission and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
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The St-Pierre lab develops and applies new tools for monitoring and interrogating brain activity with millisecond-timescale temporal resolution. We seek an energetic team member to lead our efforts to characterize and apply new light-responsive proteins in vitro and in vivo. The Research Associate will work on two types of tools: (1) genetically encoded voltage indicators (GEVIs), fluorescent biosensors that report voltage as changes in brightness, and (2) optogenetic silencers, light-gated channels that inhibit neuronal firing. Characterization of these tools requires simultaneous electrophysiological recordings and optical excitation/imaging. This position provides exciting opportunities to work with the latest optical technologies and develop new skills in two-photon voltage imaging, protein engineering, and synthetic biology. Job Duties
Prepare brain slices, dissociated neurons, or both Conduct experiments that combine electrophysiology and either optogenetic activation or optical imaging (multi-photon fluorescence microscopy) Maintain reagent and tool supply related to the experiments Maintain an electrophysiological rig, and troubleshooting if needed Analyze data using commercial software or customized data pipelines Teach techniques, procedures, and experimental design to other members of the lab Communicate research results in group meetings, national or international conferences Perform other job related duties as assigned Minimum Qualifications
Master's degree in Basic Science or a related field. Experience in lieu of degree will not be accepted. Three years of relevant experience typically as a Research Assistant, Research Technician or Postdoctoral Fellow/Associate. Department Specific Criteria
Must have experience with performingelectrophysiology indissociated neurons, brain slices or both Must have experience with dissecting rat cortical, hippocampal neurons, or both Must have experience maintaining an electrophysiology rig Preferred Qualifications
Ability to express transgenes in neurons of brain slices using viruses and/or in utero electroporation Experience with imaging neural activity (e.g. voltage or calcium) in brain slices or in vivo, using 1P and/or 2P imaging Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer. Baylor College of Medicine fosters diversity among its students, trainees, faculty, and staff as a prerequisite to accomplishing our institutional mission and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
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