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The University of Texas at Austin

Research Associate- Structural Biologist

The University of Texas at Austin, Austin, Texas, us, 78716

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Research Associate- Structural Biologist Location: Austin, TX

Salary: $60,000 + depending on qualifications

Position Duration: Expected to Continue

Hiring Department: Molecular Biosciences

Position Open To: All Applicants

Responsibilities

Express, purify, and characterize full-length and deletion constructs of group II intron and other non‑LTR retroelement reverse transcriptase and related proteins for structural analysis and biotechnological applications using Fast Protein Liquid Chromatography (FPLC) and other methods. Characterize wild‑type and mutant proteins biochemically via enzymatic assays and determine conditions for obtaining diffraction‑quality crystals and/or for cryo‑electron microscopy analysis of proteins and protein/nucleic acid complexes. Carry out biochemical and biophysical assays.

Obtain structures of reverse transcriptase and related enzymes and their nucleic acid‑protein complexes by X‑ray diffraction and/or cryo‑EM.

Write manuscripts and assist in the preparation of reports, abstracts, manuscripts and proposals. Make presentations at lab meetings. Attend lab meetings and other meetings. Order chemicals and supplies specific to current project.

Provide instruction, assistance, and mentoring to graduate students.

Required Qualifications

Ph.D. in structural biology and/or biochemistry with demonstrated productivity in these areas.

Relevant education and experience may be substituted as appropriate.

Preferred Qualifications

Ph.D. in structural biology and/or biochemistry with at least five years’ experience and demonstrated research productivity on enzymes that bind nucleic acids and/or protein‑nucleic acid complexes.

Working Conditions

Personal protection equipment (furnished)

May work around chemical fumes

May work around standard office conditions

May work around bio-hazards

May work around chemicals

Required Materials

Current curriculum vitae

Applicants selected for an interview will be required to submit a minimum of three letters of reference, at least two of which must be from referees outside of The University of Texas at Austin. (Hiring PI/supervisor cannot be a reference.) If selected, the letters of reference may be emailed to mbs_hr@austin.utexas.edu

Letter of Interest

Equal Opportunity Employer The University of Texas at Austin, as an equal opportunity/affirmative action employer, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, or veteran status in employment, educational programs and activities, and admissions.

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