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Mount Sinai Medical Center

Core Research Associate II- Shared Research Resources

Mount Sinai Medical Center, New York, New York, us, 10261

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Description The Core Research Associate II in the Transgenic and Genome Editing Core will be responsible for various tasks related to creation, validation and cryopreservation of genetically engineered mouse models (GEMMs). Specific job duties are outlined below, and include preparation of gene editing reagents, embryo production/manipulation, implantation, post-operative care, genotyping and breeding with husbandry support from the Center for Comparative Medicine and Surgery (CCMS) group. Experience with mouse handling is preferred. We are committed to providing training opportunities with new skills.

Responsibilities

Produces mouse embryos via superovulation or natural breeding.

Collects and manipulates preimplantation mouse embryos.

Surgically transfers the embryos into pseudopregnant mice followed by post-operative care.

Manages mouse colony via routine monitoring of mice, production of pseudopregnant females, breeding, tagging/biopsy, weaning and animal transfer.

Genotypes mouse tissues utilizing PCR, sequencing and other molecular biology techniques.

Assists in preparation and validation of genome editing reagents.

Cryopreserves mouse sperm and/or embryos and manages the cryo-storage database.

Coordinates import and export of frozen samples.

Produces mouse embryos via in vitro fertilization (IVF) for line recovery/importation or genome editing.

Assists in testing/implementation of new technologies.

Occasional weekend work will be required.

Performs other related duties as needed.

Ensures rigorous compliance with safety and regulatory requirements while performing assigned tasks.

Qualifications

Bachelors

3 years related experience (OR Masters + 1 year experience in related field)

Compensation Statement The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $58,824.00 - $88,236.00 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

Equal Opportunity Employer The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

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