University of Missouri-Columbia
Post Doctoral Fellow (Lorson Lab)
University of Missouri-Columbia, Columbia, Missouri, United States
Responsibilities:
Independently design, optimize, and execute experiments relevant to the mechanisms and therapeutics of SMA, SMARD, and/or CMT, including molecular and cellular techniques such as motor neuron cultures, primary cells; DNA/RNA extraction, PCR/qPCR, Western blotting, immunohistochemistry, and molecular cloning.
Manage and perform experiments on relevant mouse or other animal models (e.g., phenotyping, behavioral testing, drug administration, survival studies, surgery, and tissue collection).
Apply advanced techniques such as AAV gene therapy and assessment of various therapeutics on neuromuscular phenotypes; utilize state‑of‑the‑art methods like single‑cell/spatial transcriptomics, proteomics, or advanced microscopy (e.g., confocal, live‑cell imaging).
Maintain meticulous, up‑to‑date records of all experimental design, procedures, and results in a lab notebook.
Rigorously analyze complex datasets using appropriate statistical and bioinformatics tools.
Lead the writing and revision of manuscripts for submission to high‑impact, peer‑reviewed scientific journals.
Prepare and present research findings at weekly lab meetings, departmental seminars, and national/international scientific conferences related to neuromuscular diseases or neuroscience.
Contribute to or lead the preparation of grant proposals (e.g., fellowship applications, foundation grants) to secure independent or collaborative funding.
Qualifications: Minimum Qualifications: Ph.D. degree in neurobiology, molecular genetics, or a related field.
Candidates will be evaluated on previous experience with animal models or neurodegeneration disease.
Anticipated Hiring Range: $55,000‑$65,000 based upon experience.
Application Materials: Please provide cover letter, CV and contact information of three references.
Application Deadline: This posting will remain open until filled.
Other Information: Want to learn more directly from people that work at the Bond Life Sciences Center? Check out our latest video highlighting the important work and experiences of our team: https://mizzou.us/WorkatBondLSC
The Bond Life Sciences Center at the University of Missouri is a dynamic hub where groundbreaking research meets real‑world impact, fostering interdisciplinary collaboration among experts in diverse fields to save lives, reduce costs, and enhance everyday life.
Our mission is to transform scientific discoveries into actionable solutions addressing human and animal health, the environment, and agriculture, while sharing findings with the public through blog, events, and social media.
Join us to advance science and improve lives, one discovery at a time!
Community Information: Columbia offers a high quality of life, with small‑town friendliness and big‑city features, located in central Missouri close to St. Louis and Kansas City. It features a vibrant community with restaurants, entertainment, and festivals.
Benefit Eligibility: This position is eligible for University benefits, including medical, dental and vision plans, retirement, and educational fee discounts. For additional information, visit https://www.umsystem.edu/totalrewards/benefits.
Equal Employment Opportunity: Equal Employment Opportunity
The University of Missouri is an Equal Opportunity Employer.
To request ADA accommodations, please call the Director of Accessibility and ADA at 573‑884‑7278.
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Independently design, optimize, and execute experiments relevant to the mechanisms and therapeutics of SMA, SMARD, and/or CMT, including molecular and cellular techniques such as motor neuron cultures, primary cells; DNA/RNA extraction, PCR/qPCR, Western blotting, immunohistochemistry, and molecular cloning.
Manage and perform experiments on relevant mouse or other animal models (e.g., phenotyping, behavioral testing, drug administration, survival studies, surgery, and tissue collection).
Apply advanced techniques such as AAV gene therapy and assessment of various therapeutics on neuromuscular phenotypes; utilize state‑of‑the‑art methods like single‑cell/spatial transcriptomics, proteomics, or advanced microscopy (e.g., confocal, live‑cell imaging).
Maintain meticulous, up‑to‑date records of all experimental design, procedures, and results in a lab notebook.
Rigorously analyze complex datasets using appropriate statistical and bioinformatics tools.
Lead the writing and revision of manuscripts for submission to high‑impact, peer‑reviewed scientific journals.
Prepare and present research findings at weekly lab meetings, departmental seminars, and national/international scientific conferences related to neuromuscular diseases or neuroscience.
Contribute to or lead the preparation of grant proposals (e.g., fellowship applications, foundation grants) to secure independent or collaborative funding.
Qualifications: Minimum Qualifications: Ph.D. degree in neurobiology, molecular genetics, or a related field.
Candidates will be evaluated on previous experience with animal models or neurodegeneration disease.
Anticipated Hiring Range: $55,000‑$65,000 based upon experience.
Application Materials: Please provide cover letter, CV and contact information of three references.
Application Deadline: This posting will remain open until filled.
Other Information: Want to learn more directly from people that work at the Bond Life Sciences Center? Check out our latest video highlighting the important work and experiences of our team: https://mizzou.us/WorkatBondLSC
The Bond Life Sciences Center at the University of Missouri is a dynamic hub where groundbreaking research meets real‑world impact, fostering interdisciplinary collaboration among experts in diverse fields to save lives, reduce costs, and enhance everyday life.
Our mission is to transform scientific discoveries into actionable solutions addressing human and animal health, the environment, and agriculture, while sharing findings with the public through blog, events, and social media.
Join us to advance science and improve lives, one discovery at a time!
Community Information: Columbia offers a high quality of life, with small‑town friendliness and big‑city features, located in central Missouri close to St. Louis and Kansas City. It features a vibrant community with restaurants, entertainment, and festivals.
Benefit Eligibility: This position is eligible for University benefits, including medical, dental and vision plans, retirement, and educational fee discounts. For additional information, visit https://www.umsystem.edu/totalrewards/benefits.
Equal Employment Opportunity: Equal Employment Opportunity
The University of Missouri is an Equal Opportunity Employer.
To request ADA accommodations, please call the Director of Accessibility and ADA at 573‑884‑7278.
#J-18808-Ljbffr