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Howard Hughes Medical Institute (HHMI)

Research Technician - Reck-Peterson Lab

Howard Hughes Medical Institute (HHMI), New York, New York, us, 10261

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418 E 71st St #21, New York, NY 10021 Current HHMI Employees: apply via your Workday account. About the role

The Reck-Peterson lab studies the molecular mechanisms of intracellular transport. This Research Technician role will be responsible for contributing to the Reck-Peterson lab’s research program on fungal biology and secondary metabolite production. The genus Aspergillus are filamentous fungi that are both biomedically and agriculturally important. Current projects aim to determine how and why organelles move in this organism. We also aim to determine the cell biology of secondary metabolite production. Individual filamentous fungi species make dozens of secondary metabolites, with prominent examples including penicillin, lovastatin, and aflatoxin. Our lab uses a broad range of techniques including proteomics, genomics, metabolomics, biochemical in vitro reconstitution, fungal genetics, and live‑cell imaging. The ideal candidate will be a fungal biologist with additional skills in bioinformatics, molecular biology, and confocal microscopy. At least two years of full‑time research experience after obtaining an undergraduate degree is required. The lab fosters a strong culture of collaborative, team‑based science, and we are seeking applicants who value and thrive in this type of research environment. The lab welcomes applications from both Research Technician II and more experienced Research Technician III candidates. Compensation will be commensurate with level of experience and skill set. About Department/Lab

Dr. Reck‑Peterson’s laboratory studies the mechanisms of intracellular transport. The Reck‑Peterson lab strives to understand how this system works at molecular, cellular, and organismal scales. At a disease level they are interested in developing novel antifungals based on their fundamental studies of organelle trafficking and secondary metabolite production in fungi. They also strive to determine why defects in intracellular transport cause neurodegenerative diseases. They use a combination of approaches including protein biochemistry and in‑vitro reconstitution, single‑molecule biophysics, proteomics and genomics, fungal genetics, evolutionary analysis, mammalian cell culture, and state‑of‑the‑art live‑cell imaging. Through collaborations they have access to cryo‑electron microscopy and cryo‑electron tomography to pursue structural studies of the transport machinery. What we provide

Relocation Assistance A competitive compensation package Opportunity to work in a small, diverse, and encouraging research environment. A flexible schedule Well‑rounded training on techniques and soft skills One‑on‑one mentorship, and support/training for the next stage of your career What you’ll do

Research support: 50% Support the collaborative research environment by assisting researchers in the lab who focus on fungal biology. This will include media preparation, making new fungal strains, and performing standard molecular biology techniques (cloning, PCR, genomic DNA isolation). Independent research: 30% This role will include developing an independent research project. Lab operations: 20% Assist with lab management. This will include lab safety, ordering, and general lab maintenance. In addition to the duties specifically identified by this job description, the position will include other duties as assigned by the direct supervisor or others with supervisory authority over this position. What you bring

Education BA or BS in the biological, biomedical or biochemical sciences. Skills and abilities Research experience as an undergraduate. At least two years of additional full‑time research experience. Research Technician III candidates must have a minimum of four additional years of full‑time research experience. Fungal biology: cell culture, genetic engineering, genetics. Molecular biology methods: cloning, PCR, genomic DNA isolation. Bioinformatics experience. Ability to work both independently and in a team. Strong verbal and oral communication skills. Excellent interpersonal interaction skills. Excellent organizational skills. Excellent record keeping/ lab notebook management. Preferred qualifications

Familiarity with a coding language (Python or others). Compensation range

Research Technician II (annual) – $47,840 (minimum) - $59,800 (midpoint) - $77,740 (maximum) Research Technician III (annual) – $56,695 (minimum) - $70,900 (midpoint) - $92,115 (maximum) HHMI’s salary structure is developed based on relevant job market data. HHMI considers a candidate’s education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range. Physical requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances or other hazardous materials. Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis. Please note

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act. Compensation and benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more. HHMI is an Equal Opportunity Employer

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