Astrazeneca
Senior Scientist – Analytical Development, GPD
Location
Durham, NC
Job Description Are you an analytical scientist with robust method development experience for oral solid dosage forms and a passion for finding innovative solutions in pharmaceutical testing? AstraZeneca’s Global Product Development (GPD) team is seeking a Senior Scientist to enhance analytical development capabilities in the growing oral solid portfolio and bring innovative analytical approaches to the existing inhaled portfolio.
At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being bold, thinking big, and collaborating to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, you’re our kind of person.
In this role you will drive analytical method development, validation, product characterization and investigational testing, cGMP support, technology implementation, and play a central role in establishing and optimizing laboratory capabilities for oral solid dosage analysis. You will work collaboratively across interdisciplinary global teams, contribute to regulatory submissions, and help motivate team adoption of emerging AI/ML tools to enhance analytical data interpretation and workflow efficiency. The role is located in Durham, North Carolina, USA, but is part of AZ’s Global Product Development organization with additional sites in Gothenburg, Sweden and Macclesfield, UK.
What you will do:
Lead and perform analytical method development, validation, product characterization, and routine investigational and clinical release testing for inhaled and oral products.
Establish, equip, and optimize laboratory setups for oral solid dosage (OSD) testing capabilities.
Provide technical and strategic input on analytical issues relevant to OSD and, where required, across other modalities and dosage formats.
Author and review analytical documentation to support regulatory submissions, ensuring compliance with GMP/GxP expectations and responding to regulatory inquiries.
Champion laboratory automation technologies to improve efficiency and reliability in sample preparation, method execution, and data analysis.
Demonstrate an active interest in using AI/ML and other data science tools to enhance analytical results interpretation and workflow performance.
Minimum Qualifications:
Bachelor’s degree in Analytical Chemistry, Pharmaceutical Sciences, or a closely related field.
Minimum of 8-10 years of experience with a Bachelor’s or 4-6 years with a Master’s degree.
Minimum of 8 years of experience working with oral solid dosage forms.
Strong background in analytical development for oral solid dosage forms; preferred candidates will also have experience testing inhaled products.
Demonstrated experience in method development, validation, and application in the pharmaceutical industry.
Confirmed experience with regulatory submission processes and writing/reviewing analytical sections with response to regulatory inquiries.
Hands‑on proficiency with workflow optimization; experience with automation is preferred.
Excellent organizational, problem‑solving, and collaborative communication skills.
Experience working in a GMP/GxP environment.
Strong people, organizational, and communication skills (both written and oral).
Preferred Qualifications:
Exposure to analytical strategies for portfolios that vary across modalities and/or dosage formats, including oral solid and inhaled products.
Familiarity or interest in applying data science tools, including AI/ML, to advance analytical interpretation and data flow.
Experience collaborating in cross‑functional global teams.
Consistent track record in analytical method lifecycle management.
Experience with validation life cycle management of laboratory automation technology to meet GxP requirements.
Why AstraZeneca At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your spirit. There’s no better place to make a difference in medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development.
So What’s Next Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!
Find out more on Social Media
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About Operations
Date Posted
02-Dec-2025
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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Job Description Are you an analytical scientist with robust method development experience for oral solid dosage forms and a passion for finding innovative solutions in pharmaceutical testing? AstraZeneca’s Global Product Development (GPD) team is seeking a Senior Scientist to enhance analytical development capabilities in the growing oral solid portfolio and bring innovative analytical approaches to the existing inhaled portfolio.
At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being bold, thinking big, and collaborating to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, you’re our kind of person.
In this role you will drive analytical method development, validation, product characterization and investigational testing, cGMP support, technology implementation, and play a central role in establishing and optimizing laboratory capabilities for oral solid dosage analysis. You will work collaboratively across interdisciplinary global teams, contribute to regulatory submissions, and help motivate team adoption of emerging AI/ML tools to enhance analytical data interpretation and workflow efficiency. The role is located in Durham, North Carolina, USA, but is part of AZ’s Global Product Development organization with additional sites in Gothenburg, Sweden and Macclesfield, UK.
What you will do:
Lead and perform analytical method development, validation, product characterization, and routine investigational and clinical release testing for inhaled and oral products.
Establish, equip, and optimize laboratory setups for oral solid dosage (OSD) testing capabilities.
Provide technical and strategic input on analytical issues relevant to OSD and, where required, across other modalities and dosage formats.
Author and review analytical documentation to support regulatory submissions, ensuring compliance with GMP/GxP expectations and responding to regulatory inquiries.
Champion laboratory automation technologies to improve efficiency and reliability in sample preparation, method execution, and data analysis.
Demonstrate an active interest in using AI/ML and other data science tools to enhance analytical results interpretation and workflow performance.
Minimum Qualifications:
Bachelor’s degree in Analytical Chemistry, Pharmaceutical Sciences, or a closely related field.
Minimum of 8-10 years of experience with a Bachelor’s or 4-6 years with a Master’s degree.
Minimum of 8 years of experience working with oral solid dosage forms.
Strong background in analytical development for oral solid dosage forms; preferred candidates will also have experience testing inhaled products.
Demonstrated experience in method development, validation, and application in the pharmaceutical industry.
Confirmed experience with regulatory submission processes and writing/reviewing analytical sections with response to regulatory inquiries.
Hands‑on proficiency with workflow optimization; experience with automation is preferred.
Excellent organizational, problem‑solving, and collaborative communication skills.
Experience working in a GMP/GxP environment.
Strong people, organizational, and communication skills (both written and oral).
Preferred Qualifications:
Exposure to analytical strategies for portfolios that vary across modalities and/or dosage formats, including oral solid and inhaled products.
Familiarity or interest in applying data science tools, including AI/ML, to advance analytical interpretation and data flow.
Experience collaborating in cross‑functional global teams.
Consistent track record in analytical method lifecycle management.
Experience with validation life cycle management of laboratory automation technology to meet GxP requirements.
Why AstraZeneca At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your spirit. There’s no better place to make a difference in medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development.
So What’s Next Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!
Find out more on Social Media
About Operations
Date Posted
02-Dec-2025
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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