University of South Florida
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Sr. Biological Scientist
role at
University of South Florida .
Job Description This position reports to the USF Genomics Program Director and the Genomics Sequencing Core Director. The candidate will provide guidance, scientific and technical support to projects involving Next Generation Sequencing (NGS) and assist in management of the USF Genomics Program Core laboratory. The candidate will deliver high-quality sequencing services, including advanced single-cell and spatial sample preparation and sequencing. Responsibilities include QC of DNA, RNA, and single-cell samples, library preparation, spatial genomics method sequencing set‑up, and data delivery. Spatial genomics methods are cutting‑edge techniques that require extensive training to perform. The candidate must manage multiple projects concurrently, coordinate between several groups, and maintain excellent communication and interpersonal skills.
Perform Next‑Generation Sequencing (NGS) sample preparation and sequencing, including single‑cell RNA‑seq (scRNA‑seq, snRNA‑seq) and spatial transcriptomics (Visium HD) workflows, DNA/RNA library construction, Illumina sequencing, Nanopore sequencing, and Visium HD tissue sample preparation.
Operate and maintain high‑throughput sequencing instruments (e.g., Illumina NovaSeq X, MiSeq i100) and single‑cell systems (e.g., 10x Genomics Chromium X, Visium CytAssist).
Manage and prioritize daily laboratory workflow to ensure timely project completion within standard operating hours.
Conduct quality control (QC) assessments for RNA/DNA samples and sequencing libraries to ensure accuracy and integrity. Work closely with core users and internal team to troubleshoot, optimize protocols, and achieve consistent, high‑quality results.
Maintain accurate documentation in iLab, including experimental records, billing, reagent usage, and equipment logs, ensuring compliance with institutional standards.
Contribute to laboratory training, SOP development, and continuous process improvement initiatives to enhance efficiency and performance.
Qualifications Minimum Qualifications This position requires a Bachelor’s degree in a natural or medical science and 2 years of research experience; or a Master’s degree in a natural science. Progressively responsible experience involving scientific laboratory or field work may be substituted for the Bachelor’s degree.
Preferred Qualifications
Hands‑on experience with NGS workflows, including DNA/RNA sequencing, single‑cell, and spatial transcriptomics assays.
Master’s degree in Molecular Biology, Genomics, or a closely related field, and at least two (2) years of professional experience in a research or technical laboratory.
Hands‑on experience with Illumina and/or Nanopore sequencing platforms.
Strong organizational and time‑management skills to maintain daily operational efficiency and meet project deadlines.
Excellent teamwork, communication, and documentation skills.
Experience with 10x Genomics Chromium or Visium HD platforms is highly desirable.
Degree Equivalency Clause Four years of direct experience for a bachelor’s degree.
About Us With approximately 16,000 employees, the University of South Florida is one of the largest employers in the Tampa Bay area. We are dedicated to cultivating a talented, engaged and driven workforce that strives to be bold. Employees excel in USF’s rich academic environment, which fosters their development and advancement. In 2025, Forbes recognized USF as one of Florida’s best large employers, ranked No. 1 among the state’s 12 public universities. Our first‑class benefits package includes medical, dental and life insurance plans, retirement plan options, employee and dependent tuition programs, generous leave, and hundreds of employee perks and discounts.
Compliance and Federal Notices This position may be subject to a Level 1 or Level 2 criminal background check.
Applicants have rights under Federal Employment Laws.
The University of South Florida is an equal opportunity employer that does not discriminate against any employee or applicant for employment based on any characteristic protected by law. The University maintains programs for protected veterans and individuals with disabilities in accordance with all applicable federal and state laws.
Equal Employment Opportunity The University of South Florida is an equal opportunity employer that does not discriminate against any employee or applicant for employment based on any characteristic protected by law. The University maintains affirmative action programs for protected veterans and individuals with disabilities in accordance with all applicable federal and state laws. This job description does not constitute an employment contract.
Seniority Level Mid‑Senior level
Employment Type Full‑time
Job Function Research, Analyst, and Information Technology
Industries Higher Education
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Sr. Biological Scientist
role at
University of South Florida .
Job Description This position reports to the USF Genomics Program Director and the Genomics Sequencing Core Director. The candidate will provide guidance, scientific and technical support to projects involving Next Generation Sequencing (NGS) and assist in management of the USF Genomics Program Core laboratory. The candidate will deliver high-quality sequencing services, including advanced single-cell and spatial sample preparation and sequencing. Responsibilities include QC of DNA, RNA, and single-cell samples, library preparation, spatial genomics method sequencing set‑up, and data delivery. Spatial genomics methods are cutting‑edge techniques that require extensive training to perform. The candidate must manage multiple projects concurrently, coordinate between several groups, and maintain excellent communication and interpersonal skills.
Perform Next‑Generation Sequencing (NGS) sample preparation and sequencing, including single‑cell RNA‑seq (scRNA‑seq, snRNA‑seq) and spatial transcriptomics (Visium HD) workflows, DNA/RNA library construction, Illumina sequencing, Nanopore sequencing, and Visium HD tissue sample preparation.
Operate and maintain high‑throughput sequencing instruments (e.g., Illumina NovaSeq X, MiSeq i100) and single‑cell systems (e.g., 10x Genomics Chromium X, Visium CytAssist).
Manage and prioritize daily laboratory workflow to ensure timely project completion within standard operating hours.
Conduct quality control (QC) assessments for RNA/DNA samples and sequencing libraries to ensure accuracy and integrity. Work closely with core users and internal team to troubleshoot, optimize protocols, and achieve consistent, high‑quality results.
Maintain accurate documentation in iLab, including experimental records, billing, reagent usage, and equipment logs, ensuring compliance with institutional standards.
Contribute to laboratory training, SOP development, and continuous process improvement initiatives to enhance efficiency and performance.
Qualifications Minimum Qualifications This position requires a Bachelor’s degree in a natural or medical science and 2 years of research experience; or a Master’s degree in a natural science. Progressively responsible experience involving scientific laboratory or field work may be substituted for the Bachelor’s degree.
Preferred Qualifications
Hands‑on experience with NGS workflows, including DNA/RNA sequencing, single‑cell, and spatial transcriptomics assays.
Master’s degree in Molecular Biology, Genomics, or a closely related field, and at least two (2) years of professional experience in a research or technical laboratory.
Hands‑on experience with Illumina and/or Nanopore sequencing platforms.
Strong organizational and time‑management skills to maintain daily operational efficiency and meet project deadlines.
Excellent teamwork, communication, and documentation skills.
Experience with 10x Genomics Chromium or Visium HD platforms is highly desirable.
Degree Equivalency Clause Four years of direct experience for a bachelor’s degree.
About Us With approximately 16,000 employees, the University of South Florida is one of the largest employers in the Tampa Bay area. We are dedicated to cultivating a talented, engaged and driven workforce that strives to be bold. Employees excel in USF’s rich academic environment, which fosters their development and advancement. In 2025, Forbes recognized USF as one of Florida’s best large employers, ranked No. 1 among the state’s 12 public universities. Our first‑class benefits package includes medical, dental and life insurance plans, retirement plan options, employee and dependent tuition programs, generous leave, and hundreds of employee perks and discounts.
Compliance and Federal Notices This position may be subject to a Level 1 or Level 2 criminal background check.
Applicants have rights under Federal Employment Laws.
The University of South Florida is an equal opportunity employer that does not discriminate against any employee or applicant for employment based on any characteristic protected by law. The University maintains programs for protected veterans and individuals with disabilities in accordance with all applicable federal and state laws.
Equal Employment Opportunity The University of South Florida is an equal opportunity employer that does not discriminate against any employee or applicant for employment based on any characteristic protected by law. The University maintains affirmative action programs for protected veterans and individuals with disabilities in accordance with all applicable federal and state laws. This job description does not constitute an employment contract.
Seniority Level Mid‑Senior level
Employment Type Full‑time
Job Function Research, Analyst, and Information Technology
Industries Higher Education
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