Rutgers University
Postdoctoral Associate in Structural Biology and Biophysics
Rutgers University, Piscataway, New Jersey, United States
Postdoctoral Associate in Structural Biology and Biophysics
Posting Summary: The Deaconescu Lab at Rutgers University, located in the Quantitative Biomedicine Institute, is looking for a Postdoctoral Associate in Structural Biology and Biophysics. The laboratory focuses on microbial stress responses, especially DNA damage and the mechanochemistry of DNA‑based motors, using biochemical, biophysical and structural techniques such as X‑ray crystallography, SAXS and cryo‑EM.
Position Details
Posting Number: 25FA0742
Position Status: Full Time
Salary: $63,968 (subject to adjustment)
Benefits
Medical, prescription drug, and dental coverage
Paid vacation, holidays, and various leave programs
Competitive retirement benefits, including defined contribution plans and voluntary tax‑deferred savings options
Employee and dependent educational benefits (when applicable)
Life insurance coverage
Employee discount programs
Responsibilities
Design, execute, and analyze micro‑ and macro‑scale experiments in structural biology and biophysics.
Apply X‑ray crystallography, SAXS, cryo‑EM and related biophysical techniques to investigate DNA‑based motor mechanisms.
Perform protein expression, purification and complex formation with nucleic acids.
Develop and optimize molecular and cellular assays for mechanistic studies.
Maintain detailed laboratory records and prepare high‑quality scientific manuscripts and grant proposals.
Collaborate cross‑functionally within the laboratory and with external collaborators.
Qualifications Minimum Education and Experience
Ph.D. in structural biology, biochemistry, biophysics or a related field.
Demonstrated track record of publications in peer‑reviewed journals.
Solid experience with protein biochemistry.
Prior knowledge of crystallography and/or single‑particle electron microscopy is highly desirable.
Excellent spoken and written English; ability to work independently and in a team.
New Ph.D. graduates are encouraged to apply.
Required Knowledge, Skills, and Abilities
Proficiency in molecular biology, protein expression, and purification.
Experience with biophysical methods such as EMSA, ITC, AUC, fluorescence anisotropy, BLI, MST, CD.
Comfortable using Linux.
Strong written and oral communication skills for manuscript and grant preparation.
Preferred Qualifications
Experience with assay development and molecular microbiology.
Knowledge of cryo‑EM workflow and software.
Familiarity with laboratory equipment such as Biorad NGC, Mosquito robot, centrifuges, PCR cyclers, GelDoc, and cell culture incubators.
Access to state‑of‑the‑art cryo‑EM facility and other advanced instrumentation.
Physical Demands and Work Environment Typical lab work including handling chemicals, operating cryo‑EM machinery, and prolonged microscope usage. The candidate should be comfortable with the physical demands of laboratory research.
Compliance with Rutgers University immunization policies may require proof of seasonal influenza vaccination during the initial Flu Season, unless medical or religious exemption is granted.
All offers of employment are contingent upon successful completion of all pre‑employment screenings.
Equal Employment Opportunity Statement It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership, gender identity or expression, disability status, military service status, protected veteran status, sexual orientation, or any other category protected by law. As an institution, we encourage all qualified applicants to apply. For additional information please see the Non‑Discrimination Statement at http://uhr.rutgers.edu/non-discrimination-statement.
Posting Specific Questions Required Documents:
Resume/CV
Optional Documents:
Transcript (Unofficial)
List of Professional References (contact Info)
#J-18808-Ljbffr
Position Details
Posting Number: 25FA0742
Position Status: Full Time
Salary: $63,968 (subject to adjustment)
Benefits
Medical, prescription drug, and dental coverage
Paid vacation, holidays, and various leave programs
Competitive retirement benefits, including defined contribution plans and voluntary tax‑deferred savings options
Employee and dependent educational benefits (when applicable)
Life insurance coverage
Employee discount programs
Responsibilities
Design, execute, and analyze micro‑ and macro‑scale experiments in structural biology and biophysics.
Apply X‑ray crystallography, SAXS, cryo‑EM and related biophysical techniques to investigate DNA‑based motor mechanisms.
Perform protein expression, purification and complex formation with nucleic acids.
Develop and optimize molecular and cellular assays for mechanistic studies.
Maintain detailed laboratory records and prepare high‑quality scientific manuscripts and grant proposals.
Collaborate cross‑functionally within the laboratory and with external collaborators.
Qualifications Minimum Education and Experience
Ph.D. in structural biology, biochemistry, biophysics or a related field.
Demonstrated track record of publications in peer‑reviewed journals.
Solid experience with protein biochemistry.
Prior knowledge of crystallography and/or single‑particle electron microscopy is highly desirable.
Excellent spoken and written English; ability to work independently and in a team.
New Ph.D. graduates are encouraged to apply.
Required Knowledge, Skills, and Abilities
Proficiency in molecular biology, protein expression, and purification.
Experience with biophysical methods such as EMSA, ITC, AUC, fluorescence anisotropy, BLI, MST, CD.
Comfortable using Linux.
Strong written and oral communication skills for manuscript and grant preparation.
Preferred Qualifications
Experience with assay development and molecular microbiology.
Knowledge of cryo‑EM workflow and software.
Familiarity with laboratory equipment such as Biorad NGC, Mosquito robot, centrifuges, PCR cyclers, GelDoc, and cell culture incubators.
Access to state‑of‑the‑art cryo‑EM facility and other advanced instrumentation.
Physical Demands and Work Environment Typical lab work including handling chemicals, operating cryo‑EM machinery, and prolonged microscope usage. The candidate should be comfortable with the physical demands of laboratory research.
Compliance with Rutgers University immunization policies may require proof of seasonal influenza vaccination during the initial Flu Season, unless medical or religious exemption is granted.
All offers of employment are contingent upon successful completion of all pre‑employment screenings.
Equal Employment Opportunity Statement It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership, gender identity or expression, disability status, military service status, protected veteran status, sexual orientation, or any other category protected by law. As an institution, we encourage all qualified applicants to apply. For additional information please see the Non‑Discrimination Statement at http://uhr.rutgers.edu/non-discrimination-statement.
Posting Specific Questions Required Documents:
Resume/CV
Optional Documents:
Transcript (Unofficial)
List of Professional References (contact Info)
#J-18808-Ljbffr