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Mount Sinai Medical Center

Postdoctoral Fellow-MSH-13500-006

Mount Sinai Medical Center, New York, New York, us, 10261

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Job Title

Postdoctoral Fellow

Department

Surgery

Location

Annenberg, 25 th

Fl, RM A25-70

PI / Supervisor

David Sachs , 917-582-4676, david.sachs@mssm.edu

Administrative Contact

Stella Cherepashensky , 212-241-7120, stella.cherepashensky@mountsinai.org

Responsibilities

This research project in the Sachs laboratory focuses on the development of integrated human organoid and organ‑on‑chip models that combine cardiac, hepatic, and hematopoietic compartments to study drug responses and disease mechanisms. Experimental approaches include 3D culture systems, microfluidic platforms, advanced imaging, and quantitative computational analysis.

This position requires expertise in human pluripotent stem cell culture and differentiation, 3D organoid culture, and microphysiological systems. Techniques include flow cytometry and cell sorting, immunofluorescence and confocal microscopy, qPCR and RNA‑based analyses, protein assays, and functional phenotyping of cardiac, hepatic, and hematopoietic tissues. Responsibilities also include experimental design, data analysis, troubleshooting complex multi‑lineage systems, protocol development and optimization, and interaction with bioengineering collaborators.

Qualifications

Expertise in human pluripotent stem cell culture and differentiation, 3D organoid culture, and microphysiological systems.

Proficiency in flow cytometry, cell sorting, immunofluorescence, confocal microscopy, qPCR, RNA analysis, protein assays, and functional phenotyping of cardiac, hepatic, and hematopoietic tissues.

Ability to design experiments, analyze data, troubleshoot multi‑lineage systems, develop and optimize protocols, and collaborate with bioengineering teams.

Compensation

The salary range for this role is $72,500–$80,000 annually.

Equal Opportunity Statement

The Mount Sinai Health System is an equal‑opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law.

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