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Cold Spring Harbor Laboratory

Postdoctoral Fellow - Beyaz Lab

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States, 11724

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Postdoctoral Fellow – Beyaz Lab Position Description

Cold Spring Harbor Laboratory (CSHL) invites applications for a Postdoctoral Fellow position in the laboratory of Dr. Semir Beyaz. A successful candidate will have completed PhD training in biomedical sciences, preferably in immunology, metabolism, cancer biology, epigenetics or microbiology. We are looking for an experienced and highly motivated scientist to join a collaborative team of scientists in our lab. The successful candidate will work on developing novel approaches to enhance the efficacy of immunotherapy in treatment resistant cancers by modulating nutrient metabolism. This exciting project is funded by a National Cancer Institute R37 MERIT Award (R37CA292807). In addition, the candidate will have the opportunity to work in collaboration with a leading US-based venture capital firm and biotech company for developing new skills on the process of translating discoveries from bench to bedside.

The Beyaz lab aims to understand how nutrients and metabolism influence cellular networks that govern tissue regeneration, cancer and immunity. We dissect the precise mechanisms of how reciprocal interactions between tissue stem cells, immune cells and the microbiome affect tissue fitness or cancer outcomes. We utilize state‑of‑the‑art experimental and computational approaches to integrate genetic, epigenetic, metabolism and microbiome data to identify causal targets that can be therapeutically exploited. To assess therapeutic potential of our discoveries, we have established a comprehensive and inclusive biobank with tissue specimens, autologous patient‑derived organoids and immune cell co‑culture systems from patients across diverse ancestries. The successful candidate will have access to all of these resources in the Beyaz lab and work in partnership with our clinical collaborators to develop highly effective cancer immunotherapy modalities with minimal toxicity to host.

Position Requirements

Education: PhD in biomedical sciences, ideally in immunology, metabolism, cancer biology, epigenetics or microbiology.

Skills and experience: Significant experience in molecular biology and mouse models of cancer. Having publications in the fields of metabolism, immunology, epigenetics or cancer therapeutics will be an advantage.

Supplemental Information

How to Apply

For immediate consideration please apply to the opening found here:

Environment

Cold Spring Harbor Laboratory is a world‑renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. CSHL provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program.

Compensation and Benefits

Our employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, paid time off and a range of recognition and wellness programs. The salary range or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and/or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity).

Cold Spring Harbor Laboratory is an EO Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, or protected veteran status.

Other Benefits

Cold Spring Harbor Laboratory Postdoctoral Fellows are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, paid time off, relocation reimbursement, a Wellness Center and access to an affordable and licensed on‑site childcare center.

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