Charles River Laboratories
Senior Manager, Bioanalytical Chemistry
Charles River Laboratories, Cleveland, Ohio, us, 44101
Job Summary
A Senior Manager within the Lab Sciences disciplines is responsible for providing general oversight and management of staff assigned to multiple functions. This individual is expected to provide leadership and guidance for staff development; verify staff compliance with regulatory and other requirements; develop efficient and scientifically valid processes and procedures. They will contribute knowledge to quality metrics, performance metrics, and project risk assessments. They may function as a Principal Investigator, Individual Scientist and/or Project Scientist if required.
This role will involve direct oversight of research scientists involved with method development, study coordination, and GLP regulatory conduct. The senior manager will have specialized experience related to running a Bioanalytical GLP laboratory especially method development and project scientist responsibilities. This position will work with Operations management to assess laboratory capacity, schedule activities, and maintain laboratory production. Additional responsibilities include working with management to maintain laboratory quality, conduct training, metric analysis, and participate in process improvement initiatives.
Essential Duties And Responsibilities
Efficiently perform supervisory responsibilities in accordance with organizational policies and applicable laws to include interviewing, hiring, training and developing employees.
Effectively demonstrates the behaviors and performance characteristics as described in the CRL DNA.
Develop organizational strength by hiring, identifying and developing personnel who are scientifically and/or technically strong.
Establish a positive culture and atmosphere to maintain good retention and low turnover using available tools and metrics (e.g. Glint survey results).
Provides effective short- and long‑term solutions that support continuous improvement.
Maintain critical thinking, troubleshooting and time‑management skills aligned with the needs of operational areas.
Consistently demonstrates role‑model leadership and effective communication skills through informal discussions with peers, supervisor, and team.
Ensure laboratory tasks and operations are executed in compliance with SOPs, protocols, regulatory requirements.
Effectively establish and accurately review Standard Operating Procedures (SOPs), protocols, policies, best practices and study procedures.
Maintain contemporaneous knowledge of regulatory requirements.
Effectively plan, assign and direct work within one operational area with expanded scope and/or complexity.
Establish and actively monitor performance metrics for operational area.
Demonstrate consistent enforcement of policies with employees and manage performance based on the requirements of the employee’s role. Effectively apply progressive discipline as required.
Actively communicate and effectively collaborate and build strong working relationships with multiple departments within the site.
Demonstrated ability to function as a Principal Investigator, Individual Scientist, and/or Project Scientist as required by operational area or resourcing need.
Effectively assist in providing accurate costing estimates for components of applicable studies.
Skillfully oversee the design, conduct, interpretation and reporting of studies as required by operational area.
Effectively utilize project management systems.
Effectively lead implementation of new procedures and refinement of existing procedures to meet current and future business needs.
Effectively align operational resources with the current needs in one operational area.
Actively manage cross‑service line interdependencies in collaboration with organizational leadership.
Education
Bachelor’s degree or equivalent with 9‑12 years of relevant experience. With at least 4 years of management experience required.
Job Qualifications
Experience: An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
Certification/Licensure: None.
Other
Ability to communicate verbally and in writing at all levels inside and outside the organization.
Basic familiarity with Microsoft Office Suite.
Computer skills, commensurate with Essential Functions, including the ability to learn a validated system.
Ability to work extended hours beyond normal work schedule to include, but not limited to, evenings, weekends, extended shifts, and/or extra shifts, sometimes on short notice.
Ability to work under specific time constraints.
Workplace Requirements
While performing the duties of this job, the employee must be able to perform general office and/or laboratory procedures, which require talking, hearing, standing, or sitting for long periods of time, typing/entering data into a computer, using appropriate instruments, reaching with hands and arms, and wearing safety equipment (PPE) according to OSHA regulations and company standards.
Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus.
General office working conditions, the noise level in the work environment is usually quiet.
While performing the duties of this job the employee may occasionally be required to wear protective clothing (goggles, face shield, surgical mask, cap, gloves, scrubs, boots), work near toxic or caustic chemicals, work with biohazards, and/or work with live animals with risk of exposure to allergens and/or zoonotic diseases.
The employee may occasionally be exposed to fumes or airborne particles, unpleasant odors, and/or wet, humid and/or extreme temperature conditions.
Authorized to Work in the United States Must be authorized to work in the United States without a sponsor visa.
Pay Range The pay range for this position is $105‑130k/year. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
About Safety Assessment Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state‑of‑the‑art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River Charles River is an early‑stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non‑GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well‑being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years. We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work‑life balance flexibility.
Equal Employment Opportunity Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws. It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e‑mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit www.criver.com.
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This role will involve direct oversight of research scientists involved with method development, study coordination, and GLP regulatory conduct. The senior manager will have specialized experience related to running a Bioanalytical GLP laboratory especially method development and project scientist responsibilities. This position will work with Operations management to assess laboratory capacity, schedule activities, and maintain laboratory production. Additional responsibilities include working with management to maintain laboratory quality, conduct training, metric analysis, and participate in process improvement initiatives.
Essential Duties And Responsibilities
Efficiently perform supervisory responsibilities in accordance with organizational policies and applicable laws to include interviewing, hiring, training and developing employees.
Effectively demonstrates the behaviors and performance characteristics as described in the CRL DNA.
Develop organizational strength by hiring, identifying and developing personnel who are scientifically and/or technically strong.
Establish a positive culture and atmosphere to maintain good retention and low turnover using available tools and metrics (e.g. Glint survey results).
Provides effective short- and long‑term solutions that support continuous improvement.
Maintain critical thinking, troubleshooting and time‑management skills aligned with the needs of operational areas.
Consistently demonstrates role‑model leadership and effective communication skills through informal discussions with peers, supervisor, and team.
Ensure laboratory tasks and operations are executed in compliance with SOPs, protocols, regulatory requirements.
Effectively establish and accurately review Standard Operating Procedures (SOPs), protocols, policies, best practices and study procedures.
Maintain contemporaneous knowledge of regulatory requirements.
Effectively plan, assign and direct work within one operational area with expanded scope and/or complexity.
Establish and actively monitor performance metrics for operational area.
Demonstrate consistent enforcement of policies with employees and manage performance based on the requirements of the employee’s role. Effectively apply progressive discipline as required.
Actively communicate and effectively collaborate and build strong working relationships with multiple departments within the site.
Demonstrated ability to function as a Principal Investigator, Individual Scientist, and/or Project Scientist as required by operational area or resourcing need.
Effectively assist in providing accurate costing estimates for components of applicable studies.
Skillfully oversee the design, conduct, interpretation and reporting of studies as required by operational area.
Effectively utilize project management systems.
Effectively lead implementation of new procedures and refinement of existing procedures to meet current and future business needs.
Effectively align operational resources with the current needs in one operational area.
Actively manage cross‑service line interdependencies in collaboration with organizational leadership.
Education
Bachelor’s degree or equivalent with 9‑12 years of relevant experience. With at least 4 years of management experience required.
Job Qualifications
Experience: An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
Certification/Licensure: None.
Other
Ability to communicate verbally and in writing at all levels inside and outside the organization.
Basic familiarity with Microsoft Office Suite.
Computer skills, commensurate with Essential Functions, including the ability to learn a validated system.
Ability to work extended hours beyond normal work schedule to include, but not limited to, evenings, weekends, extended shifts, and/or extra shifts, sometimes on short notice.
Ability to work under specific time constraints.
Workplace Requirements
While performing the duties of this job, the employee must be able to perform general office and/or laboratory procedures, which require talking, hearing, standing, or sitting for long periods of time, typing/entering data into a computer, using appropriate instruments, reaching with hands and arms, and wearing safety equipment (PPE) according to OSHA regulations and company standards.
Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus.
General office working conditions, the noise level in the work environment is usually quiet.
While performing the duties of this job the employee may occasionally be required to wear protective clothing (goggles, face shield, surgical mask, cap, gloves, scrubs, boots), work near toxic or caustic chemicals, work with biohazards, and/or work with live animals with risk of exposure to allergens and/or zoonotic diseases.
The employee may occasionally be exposed to fumes or airborne particles, unpleasant odors, and/or wet, humid and/or extreme temperature conditions.
Authorized to Work in the United States Must be authorized to work in the United States without a sponsor visa.
Pay Range The pay range for this position is $105‑130k/year. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
About Safety Assessment Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state‑of‑the‑art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River Charles River is an early‑stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non‑GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well‑being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years. We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work‑life balance flexibility.
Equal Employment Opportunity Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws. It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e‑mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit www.criver.com.
#J-18808-Ljbffr