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SystImmune Inc.

Sr. Manager/Associate Director Statistical Programming

SystImmune Inc., Redmond, Washington, United States, 98052

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SystImmune is a leading and well‑funded clinical‑stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi‑specific, multi‑specific antibodies, and antibody‑drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications, alongside ongoing clinical trials and a robust preclinical pipeline of potential cancer therapeutics in the discover and IND‑enabling stages, representing cutting‑edge biologics development.

SystImmune is seeking a

Senior Manager or Associate Director of Statistical Programming

to lead statistical programming activities across complex clinical development programs. This role oversees high‑quality, on‑time delivery of datasets, TLGs, and regulatory submissions, manages and develops programming teams and vendors, and serves as the programming lead on key studies. The position partners closely with biostatistics and cross‑functional teams to support study design, regulatory readiness, and continuous improvement of programming standards and processes. It can be based in

Sugar Land, TX, Princeton, NJ, or Redmond, WA.

This is a bilingual role in Chinese and English.

Responsibilities

Responsible for statistical programming activities within a therapeutic project or equivalent

Lead, manage, develop and support statistical programming team

Manage critical deadlines, demonstrate problem‑solving ability, and ensure quality statistical programming deliverables will be completed within designated timeframe

Serve as project leader on studies or tasks of greater complexity

Attend multidisciplinary team meetings, representing the statistical programming function

Create or review and approve programming plans at study and project level

Provide input on key study‑related documents produced by other functions (e.g., CRFs, Data Management Plan, SAPs, etc.)

Provide programming leadership for preparation of datasets and TLGs (NDA/BLA) to FDA, EMA, or other worldwide regulatory agencies

Develop software systems to generate displays of clinical study data as tables, listings, and graphs for electronic submission to regulatory agencies

Assist statisticians by suggesting algorithms to address novel analysis requests

Develop software validation procedures and test plans, as necessary

Create and document archives of software, outputs, and analysis files

Contribute to the creation and maintenance of department SOPs related to clinical data analysis

Review draft clinical reports, journal articles, slide presentations, and other documents to assure that results are reported accurately

Oversee work of internal contract programmers and external vendors

Provide time and resource estimates for project planning

Requirements

BSc or MS (in a numerate discipline, preferably in Statistics, Computer Science, or Mathematics)

Preferably at least 10 years of experience in biostatistics or statistical programming activities in the Pharmaceutical/Biotechnology industry in clinical development

At least 5 years of experience as a statistical programming team leader or manager

Fluency in English and Chinese

Strong knowledge of relevant regulatory (FDA, NMPA, EMA, PMDA, etc.) and data submission guidelines

Strong understanding of drug development, including knowledge of interfaces and interdependencies with other functions

Consistent experience as a lead statistical programmer on several concurrent NDA projects

Strong knowledge of the relevant therapeutic areas and CDISC standards

Self‑directed, technically strong, and a recognized leader maintaining a strategic prospective with regard to statistical programming processes, management of statistical programmers and customer management

Strong project management skills

Compensation and Benefits The expected base salary range for this position is $150,000 – $200,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills. While most offers typically fall within the low to mid‑point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.

We offer a comprehensive benefits package including: 100% paid employee premiums for medical, dental, and vision; STD; LTD; a 401(k) plan with a 50% company match up to 3% and a vesting schedule of only 5 years; 15 PTO days per year; sick leave; plus 11 paid holidays and more.

SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

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