Syneos Health, Inc.
Sr Biostatistician-Sr Data Scientist/Analyst (US and UK Only)
Syneos Health, Inc., Morrisville, North Carolina, United States, 27560
Sr Biostatistician-Sr Data Scientist/Analyst (US and UK Only)
Updated:
January 9, 2026 Location:
Morrisville, NC, United States Job ID:
25103480-OTHLOC-1500-2DNY-2DR
Description Sr Biostatistician-Sr Data Scientist/Analyst (US and UK Only)
Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.
Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.
Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.
Why Syneos Health WORK HERE MATTERS EVERYWHERE
We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.
Job Responsibilities Must be located in the United States or UK with no sponsorship needs to be considered for this position.
Lead development of analysis specifications, develop programs, and conduct analyses while providing technical guidance for Real World Data (RWD) research. Ensure quality standards and methodological rigor across projects through development of patient cohorts and validation of key variables.
Required Experience
Leadership of RWD analysis strategy and execution
Lead development of technical specifications and study methodology
Statistical programming proficiency (R, SAS, SQL, Python)
Oversight of quality control processes
Cross-functional team collaboration
Management of project timelines and deliverables
Development of best practices and standards
Demonstrated ability to communicate complex analyses to non-technical stakeholders
Technical Expertise
Proficiency in SAS or R & SQL is a must, expectation to be programming independently, creating packages, taking requirements, writing specifications, work with complex data structures and study design.
Experience in more complex programming, such as propensity score analysis, lines of therapy, Sankey diagram, machine learning.
Experience with complex statistical programming, such as propensity score matching.
Experience applying machine learning methods (such as LASSO, DT, RF, and XGBoost) with RWD.
Experience with OHDSI or DARWIN tool sets in R
Subject Matter Expertise
Understanding of epidemiology / outcomes research, experience with study design and execution, Biomarker/genomic data sources.
Experience with healthcare databases:
Claims (examples include Optum, MarketScan, Pharmetrics+, HealthVerity, CPRD)
Electronic Health Records (examples include IQVIA, Flatiron, Concert AI, TriNetX)
Experience with OMOP CDM or similar common data model framework.
Knowledge of US/international data sources.
For clinical trial analysis specifically, experience with psychometric validation.
Project Implementation capability (reviewing, contributing to technical review and suggesting edits, executing) in the following are expected
Statistical analysis plan development
Protocol / manuscript development
Study design and execution
Cross-functional team collaboration
Being able to track and update work in a software (Jira or ADO)
Additional Requirements
Oncology Specific: Experience in oncology observational studies, experience in Flatiron and ConcertAI, understanding of programming logic in lines of therapy.
Molecular Epidemiology Specific
Cloud-based SQL is desirable
Experience with Clinico-genomic multi-modal data (e.g., Tempus AI) or population biobank data (UK biobank)
Experience and comfort to multitasking and working in a matrix environment
Tableau or Power BI or other graphics tool is a plus
HEOR Specific
SAS/SQL required, additional experience with R beneficial
Experience with health economics and outcomes research (HEOR) methodologies, including cost analysis, burden of illness studies, and comparative effectiveness research
Minimum Qualifications
Master’s degree in Biostatistics, Epidemiology, Data Science, Bioinformatics, or related field with 5-8 years of relevant post-graduation experience, or PhD with 3+ years post-graduation experience
Advanced expertise in statistical programming and observational research methods
Comprehensive experience with healthcare data sources and analysis
Proven ability to lead projects autonomously in a matrix environment
Track record of managing priorities and performance targets
Benefits At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.
Salary Range $80,600.00 - $145,000.00
Get to know Syneos Health Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
http://www.syneoshealth.com
Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
#J-18808-Ljbffr
January 9, 2026 Location:
Morrisville, NC, United States Job ID:
25103480-OTHLOC-1500-2DNY-2DR
Description Sr Biostatistician-Sr Data Scientist/Analyst (US and UK Only)
Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.
Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.
Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.
Why Syneos Health WORK HERE MATTERS EVERYWHERE
We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.
Job Responsibilities Must be located in the United States or UK with no sponsorship needs to be considered for this position.
Lead development of analysis specifications, develop programs, and conduct analyses while providing technical guidance for Real World Data (RWD) research. Ensure quality standards and methodological rigor across projects through development of patient cohorts and validation of key variables.
Required Experience
Leadership of RWD analysis strategy and execution
Lead development of technical specifications and study methodology
Statistical programming proficiency (R, SAS, SQL, Python)
Oversight of quality control processes
Cross-functional team collaboration
Management of project timelines and deliverables
Development of best practices and standards
Demonstrated ability to communicate complex analyses to non-technical stakeholders
Technical Expertise
Proficiency in SAS or R & SQL is a must, expectation to be programming independently, creating packages, taking requirements, writing specifications, work with complex data structures and study design.
Experience in more complex programming, such as propensity score analysis, lines of therapy, Sankey diagram, machine learning.
Experience with complex statistical programming, such as propensity score matching.
Experience applying machine learning methods (such as LASSO, DT, RF, and XGBoost) with RWD.
Experience with OHDSI or DARWIN tool sets in R
Subject Matter Expertise
Understanding of epidemiology / outcomes research, experience with study design and execution, Biomarker/genomic data sources.
Experience with healthcare databases:
Claims (examples include Optum, MarketScan, Pharmetrics+, HealthVerity, CPRD)
Electronic Health Records (examples include IQVIA, Flatiron, Concert AI, TriNetX)
Experience with OMOP CDM or similar common data model framework.
Knowledge of US/international data sources.
For clinical trial analysis specifically, experience with psychometric validation.
Project Implementation capability (reviewing, contributing to technical review and suggesting edits, executing) in the following are expected
Statistical analysis plan development
Protocol / manuscript development
Study design and execution
Cross-functional team collaboration
Being able to track and update work in a software (Jira or ADO)
Additional Requirements
Oncology Specific: Experience in oncology observational studies, experience in Flatiron and ConcertAI, understanding of programming logic in lines of therapy.
Molecular Epidemiology Specific
Cloud-based SQL is desirable
Experience with Clinico-genomic multi-modal data (e.g., Tempus AI) or population biobank data (UK biobank)
Experience and comfort to multitasking and working in a matrix environment
Tableau or Power BI or other graphics tool is a plus
HEOR Specific
SAS/SQL required, additional experience with R beneficial
Experience with health economics and outcomes research (HEOR) methodologies, including cost analysis, burden of illness studies, and comparative effectiveness research
Minimum Qualifications
Master’s degree in Biostatistics, Epidemiology, Data Science, Bioinformatics, or related field with 5-8 years of relevant post-graduation experience, or PhD with 3+ years post-graduation experience
Advanced expertise in statistical programming and observational research methods
Comprehensive experience with healthcare data sources and analysis
Proven ability to lead projects autonomously in a matrix environment
Track record of managing priorities and performance targets
Benefits At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.
Salary Range $80,600.00 - $145,000.00
Get to know Syneos Health Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
http://www.syneoshealth.com
Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
#J-18808-Ljbffr