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Duke Clinical Research Institute

Registered Nurse (May Grad 2026) Peds Transplant and Cellular Therapy

Duke Clinical Research Institute, Durham, North Carolina, United States, 27703

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At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and the greater community. No matter where your talents lie, join us and discover how we can advance health together.

About Duke University Hospital

Pursue your passion for caring with Duke University Hospital in Durham, North Carolina, which is consistently ranked among the best in the United States. The largest of Duke Health's four hospitals with 1062 patient beds, it features comprehensive diagnostic and therapeutic facilities, including a regional emergency/trauma center, an endo‑surgery center, and more.

Duke Nursing Highlights:

Duke University Health System is designated as a Magnet organization

Nurses from each hospital are consistently recognized each year as North Carolina's Great 100 Nurses.

Duke University Health System was awarded the American Board of Nursing Specialties Award for Nursing Certification Advocacy for being strong advocates of specialty nursing certification.

Duke University Health System has 6000+ registered nurses

Quality of Life: Living in the Triangle!

Relocation Assistance (based on eligibility)

Registered Nurse (New Grads) - Pediatric Transplant & Cellular Therapy/Oncology

Duke University Hospital

Full Time | Day/Night Rotating

Duke University Health System seeks to hire an experienced Registered Nurse with a passion for high‑acuity, relationship‑centered pediatric care to join our Pediatric Transplant & Cellular Therapy/Oncology Unit. This team plays a vital role in Duke Children's mission of Advancing Health Together.

Unit Overview This 17‑bed blended pediatric specialty unit cares for a unique and complex patient population, including:

Stem cell transplant recipients

Cellular therapy patients (including CAR‑T)

Pediatric oncology patients with high‑risk hematologic malignancies and brain tumors

Children with sickle cell disease, metabolic disorders, and genetic conditions

The unit supports longer‑term continuity‑based care with an average length of stay of ~30 days, allowing nurses to develop deep and meaningful connections with patients and families.

Acuity Level

Transplant & cellular therapy patients: ICU‑level ("ICU light")

Oncology patients: step‑down acuity

Staffing & Support Structure

RN‑to‑patient ratio: 1:1 to 1:3 depending on acuity

Free‑standing charge nurse 24/7 (no patient assignment)

Health Unit Coordinator 24/7

Nursing Assistants/NCAs on unit daily (7a‑7p)

Multidisciplinary rounds with active RN collaboration

What You Will Do As a Clinical Nurse I, you will deliver comprehensive, evidence‑based care in alignment with the medical and nursing plans of care. Responsibilities include:

Perform thorough pediatric assessments and ongoing monitoring of high‑acuity transplant, cellular therapy, and oncology patients.

Plan, provide, and document individualized nursing care using the nursing process.

Administer chemotherapy, immunotherapy, and supportive regimens.

Provide central line management (Broviac, Port‑A‑Cath, PICC).

Administer and monitor blood products.

Identify and respond to early signs of clinical deterioration.

Educate patients and families on treatment, expectations, and home care.

Delegate and supervise care delivered by licensed and unlicensed personnel.

Serve as charge nurse or team leader as needed.

Act as a preceptor and support the growth of new staff and learners.

Contribute to clinical and operational performance improvement initiatives.

Specialized Clinical Skills You Will Develop

Chemotherapy certification

Cellular therapy and transplant competencies

Management of:

Engraftment syndrome

Graft‑versus‑host disease (GVHD)

Cytokine Release Syndrome (CRS)

Neurotoxicity (ICANS)

Advanced pediatric critical thinking and interdisciplinary communication

What You Can Expect

A fast‑paced, highly collaborative environment

Relationship‑based nursing with long‑term patients and families

Involvement in daily rounds and care planning

Opportunities to grow in one of Duke's highest‑acuity pediatric care settings

What We Provide

Paid training: 6‑8 weeks of orientation based on experience

Clinical Ladder advancement opportunities

Tuition assistance

Specialty certification bonus

Performance increases

Relocation assistance

Employee referral program

Comprehensive benefits: Medical, Dental, Vision, Pension, and more

Robust professional development through Duke's Office of Continuing Education

What You Will Need

Graduation from an accredited BSN, ADN, or Nursing Diploma program

Must be a December 2025 or May 2026 grad

RNs without a BSN must enroll in a BSN program within 2 years and complete it within 7 years

Licensure & Certifications

Current NC RN license or compact license

BLS certification required

If you are a new grad seeking to grow in a high‑acuity pediatric environment—and want to be part of a team that values compassion, competence, and collaboration—we invite you to apply.

Equal Opportunity Employer Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

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