Candel Therapeutics
Why Work With Us?
At Candel Therapetics, our people drive our success. We value diversity, collaboration, and bold thinking in a supportive, mission-driven environment. Like a team, we show up for each other and stay focused on making a difference for patients and families. Our leadership is transparent and empowering, and our culture is built on trust, flexibility, and accountability, encouraging ownership and innovation every day.
Our Science: Advancing Cancer Immunotherapies Candel Therapeutics is a clinical-stage biopharma company developing off-the-shelf, multimodal immunotherapies that stimulate personalized, systemic anti-tumor responses. Our platforms use genetically modified adenovirus and HSV constructs. With positive Phase 3 results for our lead candidate, it’s an exciting time to join us and help bring transformative cancer treatments to patients. Learn more:
www.candeltx.com
Position Summary: We’re looking for a
Clinical Trial Manager (CTM)
to help us lead execution of our Phase 3 oncology trials with precision, confidence, and heart. This is a fast-paced, high-accountability role where you’ll collaborate cross-functionally, ensure inspection readiness, and keep our clinical operations running smoothly.
If you’re a
self-motivated leader
who thrives on solving problems, navigating complexity, and working with humility, this role is for you.
What You’ll Do:
Provide operational management and leadership to cross-functional study team to execute the clinical study per agreed upon timelines, budget and quality.
Drive startup through closeout: IRB, contracting, site selection, initiation, monitoring, and metrics tracking.
Support inspection readiness and contribute to critical regulatory milestones.
Co-monitor with CRAs; review site visit reports and elevate issues proactively.
Maintain essential documents and trial master file (TMF) accuracy.
Collaborate with internal teams and vendors to ensure alignment and effective execution.
What You Bring:
4+ years
of CTM or site management experience in
oncology clinical trials is required
Deep understanding of
Phase 3 trial conduct
and in-house operational models
Familiarity with
ICH/GCP, FDA/EMA guidelines , and regulatory best practices
Strong leadership and problem-solving skills; ability to manage ambiguity and prioritize independently
Exceptional communication skills and comfort interacting with senior stakeholders
Prior CRA experience is a plus
High emotional intelligence and a “scrappy but humble” mindset
Why You’ll Succeed at Candel:
You know how to
get things done
without needing step‑by‑step instructions.
You value
collaboration over ego
and strive to lift others as you grow.
You’re excited to join a growing company and make a tangible impact.
You care about
patients, science, and people —in that order.
Work Environment: This is a
hybrid position
based in the Greater Boston area. Onsite presence of
1–2 days/week
is expected. Occasional travel (~20%) may be required for site co‑monitoring or inspections.
#J-18808-Ljbffr
Our Science: Advancing Cancer Immunotherapies Candel Therapeutics is a clinical-stage biopharma company developing off-the-shelf, multimodal immunotherapies that stimulate personalized, systemic anti-tumor responses. Our platforms use genetically modified adenovirus and HSV constructs. With positive Phase 3 results for our lead candidate, it’s an exciting time to join us and help bring transformative cancer treatments to patients. Learn more:
www.candeltx.com
Position Summary: We’re looking for a
Clinical Trial Manager (CTM)
to help us lead execution of our Phase 3 oncology trials with precision, confidence, and heart. This is a fast-paced, high-accountability role where you’ll collaborate cross-functionally, ensure inspection readiness, and keep our clinical operations running smoothly.
If you’re a
self-motivated leader
who thrives on solving problems, navigating complexity, and working with humility, this role is for you.
What You’ll Do:
Provide operational management and leadership to cross-functional study team to execute the clinical study per agreed upon timelines, budget and quality.
Drive startup through closeout: IRB, contracting, site selection, initiation, monitoring, and metrics tracking.
Support inspection readiness and contribute to critical regulatory milestones.
Co-monitor with CRAs; review site visit reports and elevate issues proactively.
Maintain essential documents and trial master file (TMF) accuracy.
Collaborate with internal teams and vendors to ensure alignment and effective execution.
What You Bring:
4+ years
of CTM or site management experience in
oncology clinical trials is required
Deep understanding of
Phase 3 trial conduct
and in-house operational models
Familiarity with
ICH/GCP, FDA/EMA guidelines , and regulatory best practices
Strong leadership and problem-solving skills; ability to manage ambiguity and prioritize independently
Exceptional communication skills and comfort interacting with senior stakeholders
Prior CRA experience is a plus
High emotional intelligence and a “scrappy but humble” mindset
Why You’ll Succeed at Candel:
You know how to
get things done
without needing step‑by‑step instructions.
You value
collaboration over ego
and strive to lift others as you grow.
You’re excited to join a growing company and make a tangible impact.
You care about
patients, science, and people —in that order.
Work Environment: This is a
hybrid position
based in the Greater Boston area. Onsite presence of
1–2 days/week
is expected. Occasional travel (~20%) may be required for site co‑monitoring or inspections.
#J-18808-Ljbffr