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Prellis Biologics, Inc.

Senior Associate Scientist-Scientist – Cell Biology and Immunology Cell Biology

Prellis Biologics, Inc., Berkeley, California, United States, 94709

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Senior Associate Scientist-Scientist – Cell Biology and Immunology

Contract Cell Biology Senior Associate Scientist/Scientist – Cell Biology & Immunology

Company Overview: Prellis Biologics is a dynamic startup revolutionizing the field of immunology. We are developing next-generation technologies to harness the full potential of the immune system, driving innovation in therapeutic development.

Position Overview: We are seeking a passionate and skilled immunologist to help advance our pioneering in vitro immune system platform. In this role, you will collaborate with a multidisciplinary team to engineer lymph node organoids, design and execute high-impact assays, and contribute to the development of immune processes and antibody engineering strategies.

Key Responsibilities: • Design, execute, and analyze complex cell-based experiments aligned with research objectives. • Isolate, culture, and maintain both primary and established immune cell lines using aseptic techniques. • Perform multiparameter flow cytometry and cell sorting for immune profiling and functional assays. • Utilize innovative approaches to stimulate and characterize immune cell responses. • Contribute scientific insight to the design and development of in vitro immune processes and antibody generation strategies. • Maintain a hands-on presence in the lab (60–80% of the time) in a fast-paced research environment. • Develop, optimize, and run immune assays, including ELISA and other protein quantification methods. • Perform basic protein assays such as Western blotting and protein quantification. • Ensure all experimental work complies with established protocols, SOPs, and regulatory standards. • Maintain accurate, detailed, and traceable experimental records. • Analyze, interpret, and present findings at internal meetings and project reviews. • Support troubleshooting, protocol refinement, and continuous improvement initiatives. • Collaborate with cross-functional teams to align project goals and share expertise.

Qualifications: • M.S. or Ph.D. in Immunology, Cell Biology, Biotechnology, or a related discipline. • 5+ years of laboratory experience in immunology or cell biology (industry experience preferred). • Strong understanding of adaptive immunity, particularly B and T cell biology. • Knowledge of cell-cell interactions and ligand-receptor signaling pathways. • Proficiency in mammalian cell culture, immune cell isolation, and maintenance. • Demonstrated expertise in flow cytometry, including panel design, staining, acquisition, and analysis. • Experience in immune functional assays, ELISA, and protein analysis techniques. • Familiarity with laboratory compliance standards, SOPs, and documentation best practices. • Strong organizational skills, attention to detail, and ability to work independently or collaboratively. • Effective verbal and written communication skills for data reporting and documentation. • Expertise in experimental design, data interpretation, and complex immunological data analysis. • Proficiency in primary cell isolation, culture, and in vitro assay development.

Preferred Skills & Experience: • Knowledge of immune tolerance, vaccine development, or systems immunology. • Experience in project management. • Background in protein or sequence bioinformatics. • Familiarity with molecular biology techniques. • Experience implementing lab systems or high-throughput screening platforms. • Skilled in data analysis tools such as FlowJo, and GraphPad Prism. • Prior experience in drug discovery, vaccine and/or antibody development.

Key Attributes: • Detail-oriented with a strong sense of responsibility for compliance and documentation. • Proactive, collaborative, and adaptable in a dynamic research setting. • Committed to scientific rigor and continuous professional development. $106,000 - $144,000 per year Join Our Team

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