Kite Pharma
Associate Research Scientist, Process Impurities Development
Kite Pharma, Santa Monica, California, United States, 90403
Associate Research Scientist, Process Impurities Development
Join to apply for the
Associate Research Scientist, Process Impurities Development
role at
Kite Pharma Associate Research Scientist, Process Impurities Development
Join to apply for the
Associate Research Scientist, Process Impurities Development
role at
Kite Pharma Direct message the job poster from Kite Pharma We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.
Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.
Job Description
We are seeking a highly motivated
Associate Research Scientist
to join our Process Impurities Development team within the Method Development and Automation function. This role focuses on the development, optimization, and validation of analytical methods supporting residual impurity testing, host cell protein (HCP) analysis, compendial testing, and raw material characterization to support gene and cell therapy manufacturing.
The successful candidate will bring strong experience with ELISA, ELLA, and molecular biology techniques, along with a working knowledge of ICH, USP, and EU regulatory guidelines for analytical method development. You will play a critical role in ensuring product safety and consistency by supporting process development and tech transfer activities across the organization.
Title : Associate Research Scientist I, Process Impurities Development
Team : Analytical Development, Process Impurities, Method Development
Reports to : Principal Scientist, Analytical Ops
Key Responsibilities
Develop and optimize analytical methods for detection and quantification of residual impurities, including Host Cell Proteins and nucleic acids Perform and validate ELISA- and ELLA-based assays for impurity profiling Execute molecular biology methods (e.g., qPCR, ddPCR) to support residual DNA or RNA detection Conduct compendial testing per USP, EP, and other regulatory guidelines for raw materials and in-process components Design and execute method validation studies in accordance with ICH, USP, and EU requirements Troubleshoot assay performance issues and implement continuous improvements Collaborate cross-functionally with Process Development, Quality, and Manufacturing teams to integrate analytical methods into development workflows Document experimental protocols, validation reports, and supporting SOPs in accordance with GDP and regulatory standards Maintain compliance with GMP and internal quality systems
Basic Qualifications
BA / BS and 4+ years of relevant experience MA / MS and 2+ years of relevant experience Degree in Biochemistry, Molecular Biology, Analytical Chemistry, or a related discipline
Preferred Qualifications
Demonstrated expertise in ELISA, ELLA (e.g., ProteinSimple Ella platform), and quantitative molecular assays Familiarity with impurity testing for biologics or gene therapies (e.g., HCP assays, residual DNA/RNA, enzyme activity) Proven experience developing and validating analytical methods in alignment with ICH Q2(R2), USP, and EU guidelines Working knowledge of compendial methods and regulatory standards (USP , , , etc.) Proficiency in data analysis using software such as SoftMax Pro, GraphPad Prism, and JMP Excellent technical writing skills for protocols, reports, and submissions Strong collaborative mindset and communication skills Comfortable working in a dynamic biotech environment with evolving priorities and timelines
The salary range for this position is: $99,705.00 - $129,030.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
https://www.gilead.com/careers/compensation-benefits-and-wellbeing
Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.
For jobs in the United States:
Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.
NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT
PAY TRANSPARENCY NONDISCRIMINATION PROVISION
Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Kite Pharma Employees and Contractors:
Please apply via the Internal Career Opportunities portal in Workday. Seniority level
Seniority level Mid-Senior level Employment type
Employment type Full-time Job function
Job function Other Referrals increase your chances of interviewing at Kite Pharma by 2x Get notified about new Associate Research Scientist jobs in
Santa Monica, CA . Senior Water Resources Engineer or Scientist
Los Angeles, CA $136,400.00-$191,900.00 2 weeks ago Malibu, CA $177,400.00-$221,800.00 4 days ago Sediment Engineer/Scientist - Mid-to-Senior Level
Long Beach, CA $95,000.00-$125,000.00 5 months ago Thousand Oaks, CA $25.00-$30.00 5 days ago Thousand Oaks, CA $32.00-$34.00 2 days ago Thousand Oaks, CA $70,000.00-$85,000.00 3 weeks ago Thousand Oaks, CA $25.00-$28.00 3 weeks ago Associate Research Scientist, 3D Generative AI
Glendale, CA $138,900.00-$186,200.00 3 weeks ago Research Associate I - Noble Lab - Lung Institute / Department of Medicine
Thousand Oaks, CA $22.00-$32.00 2 days ago Torrance, CA $135,000.00-$140,000.00 1 month ago Research Associate Data Scientist - Slomka Lab - Innovation in Imaging / Department of Medicine / Division of AIM
Los Angeles, CA $78,332.80-$133,161.59 2 weeks ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr
Join to apply for the
Associate Research Scientist, Process Impurities Development
role at
Kite Pharma Associate Research Scientist, Process Impurities Development
Join to apply for the
Associate Research Scientist, Process Impurities Development
role at
Kite Pharma Direct message the job poster from Kite Pharma We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.
Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.
Job Description
We are seeking a highly motivated
Associate Research Scientist
to join our Process Impurities Development team within the Method Development and Automation function. This role focuses on the development, optimization, and validation of analytical methods supporting residual impurity testing, host cell protein (HCP) analysis, compendial testing, and raw material characterization to support gene and cell therapy manufacturing.
The successful candidate will bring strong experience with ELISA, ELLA, and molecular biology techniques, along with a working knowledge of ICH, USP, and EU regulatory guidelines for analytical method development. You will play a critical role in ensuring product safety and consistency by supporting process development and tech transfer activities across the organization.
Title : Associate Research Scientist I, Process Impurities Development
Team : Analytical Development, Process Impurities, Method Development
Reports to : Principal Scientist, Analytical Ops
Key Responsibilities
Develop and optimize analytical methods for detection and quantification of residual impurities, including Host Cell Proteins and nucleic acids Perform and validate ELISA- and ELLA-based assays for impurity profiling Execute molecular biology methods (e.g., qPCR, ddPCR) to support residual DNA or RNA detection Conduct compendial testing per USP, EP, and other regulatory guidelines for raw materials and in-process components Design and execute method validation studies in accordance with ICH, USP, and EU requirements Troubleshoot assay performance issues and implement continuous improvements Collaborate cross-functionally with Process Development, Quality, and Manufacturing teams to integrate analytical methods into development workflows Document experimental protocols, validation reports, and supporting SOPs in accordance with GDP and regulatory standards Maintain compliance with GMP and internal quality systems
Basic Qualifications
BA / BS and 4+ years of relevant experience MA / MS and 2+ years of relevant experience Degree in Biochemistry, Molecular Biology, Analytical Chemistry, or a related discipline
Preferred Qualifications
Demonstrated expertise in ELISA, ELLA (e.g., ProteinSimple Ella platform), and quantitative molecular assays Familiarity with impurity testing for biologics or gene therapies (e.g., HCP assays, residual DNA/RNA, enzyme activity) Proven experience developing and validating analytical methods in alignment with ICH Q2(R2), USP, and EU guidelines Working knowledge of compendial methods and regulatory standards (USP , , , etc.) Proficiency in data analysis using software such as SoftMax Pro, GraphPad Prism, and JMP Excellent technical writing skills for protocols, reports, and submissions Strong collaborative mindset and communication skills Comfortable working in a dynamic biotech environment with evolving priorities and timelines
The salary range for this position is: $99,705.00 - $129,030.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
https://www.gilead.com/careers/compensation-benefits-and-wellbeing
Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.
For jobs in the United States:
Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.
NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT
PAY TRANSPARENCY NONDISCRIMINATION PROVISION
Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Kite Pharma Employees and Contractors:
Please apply via the Internal Career Opportunities portal in Workday. Seniority level
Seniority level Mid-Senior level Employment type
Employment type Full-time Job function
Job function Other Referrals increase your chances of interviewing at Kite Pharma by 2x Get notified about new Associate Research Scientist jobs in
Santa Monica, CA . Senior Water Resources Engineer or Scientist
Los Angeles, CA $136,400.00-$191,900.00 2 weeks ago Malibu, CA $177,400.00-$221,800.00 4 days ago Sediment Engineer/Scientist - Mid-to-Senior Level
Long Beach, CA $95,000.00-$125,000.00 5 months ago Thousand Oaks, CA $25.00-$30.00 5 days ago Thousand Oaks, CA $32.00-$34.00 2 days ago Thousand Oaks, CA $70,000.00-$85,000.00 3 weeks ago Thousand Oaks, CA $25.00-$28.00 3 weeks ago Associate Research Scientist, 3D Generative AI
Glendale, CA $138,900.00-$186,200.00 3 weeks ago Research Associate I - Noble Lab - Lung Institute / Department of Medicine
Thousand Oaks, CA $22.00-$32.00 2 days ago Torrance, CA $135,000.00-$140,000.00 1 month ago Research Associate Data Scientist - Slomka Lab - Innovation in Imaging / Department of Medicine / Division of AIM
Los Angeles, CA $78,332.80-$133,161.59 2 weeks ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr