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Process Development Principal Scientist - Cambridge, MA

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Process Development Principal Scientist - Cambridge, MA

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VetJobs Job Description

Job Description

ATTENTION MILITARY AFFILIATED JOB SEEKERS

- Our organization works with partner companies to source qualified talent for their open roles. The following position is available to

Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers . If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps. Unless specifically stated otherwise, this role is "On-Site" at the location detailed in the job post.

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Principal Scientist

What you will do

Skills

Let’s do this. Let’s change the world. In this vital role you will apply your knowledge and skills to perform analytical development of late-stage biological therapeutics. In your daily work you will:

Interface and collaborate with other functional areas in matrix environment, serving as analytical subject matter expert to support and advise design of characterization studies, data analysis and investigations.

Provide analytical testing support to functions including but not limited to Drug Substance Technologies, Quality, and Manufacturing

Leverage latest advances in protein analytics to develop, optimize, troubleshoot, remediate, qualify, validate and transfer analytical methods

Design and execute analytical studies to support process and product characterization for late-stage development products utilizing protein chemistry, separation sciences and mass spectrometry

Interpret results, author technical protocols, reports, analytical method descriptions and analytical CMC sections in regulatory documents

Lead project teams and/or project sub-teams to meet program goals

Provide expertise and evaluation of Amgen’s platform and analytical technologies, helping to drive innovation and efficiency within Process Development.

Auto req ID

451992BR

Minimum Education Required

Bachelors

Job_Category

Scientific Research & Development

Additional Qualifications/Responsibilities

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Scientific professional we seek is a leader with these qualifications.

Basic Qualifications

Bachelor’s degree and 7 years of Scientific experience; Or

Master’s degree and 5 years of Scientific experience; Or

Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 2 years of Scientific experience

Preferred Qualifications

Advanced degree in Analytical Chemistry or related area with extensive experience performing independent scientific research

Four or more years of experience in pharmaceutical process development with related experience in analytical support, execution of methods, and investigational testing.

Strong and in-depth expertise in multiple analytical techniques (i.e., SE-HPLC, icIEF, IEX-HPLC, RP-HPLC, CE-SDS, LC-MS); characterization of protein modifications with glycan mapping and peptide mapping.

Experience in method development, qualification, transfer, troubleshooting, method validation, and complex investigations.

Familiarity with and understanding of United States Pharmacopeia (USP) monographs and chapters, and International Conference on Harmonization (ICH) / Food & Drug Administration (FDA) mentorship documents related to analytical method transfer and validation.

Experience in authoring and review of regulatory submission product quality sections and supporting documentation. Experience preparing for and responding to RTQ, including assessment of CQAs, product quality targets and attribute risk assessment.

Strong oral and verbal communication skills, ability to interact effectively with diverse internal and external stakeholders.

Demonstrated leadership abilities including people-centric leadership and the ability to lead in a matrix environment.

Proficiency in solving complex problems, ability to work independently, proactively seek outside resources and collaborate, ability to multitask, effectively plan and follow through on complex projects.

A self-starter with strong decision-making skills, who thrives in collaborative matrix environment and can provide cross-functional leadership and mentorship to junior staff.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In Addition To The Base Salary, Amgen Offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models, including remote and hybrid work arrangements, where possible

Salary Range

148,363.00 USD - 171,657.00 USD

City*

Cambridge

State*

Massachusetts

Job Code

Pharmaceutical Pharmaceutical

Affiliate Sponsor

Amgen

Salary Range

>$100,000 Seniority level

Seniority level Not Applicable Employment type

Employment type Full-time Job function

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