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Twist Bioscience is a company that synthesizes genes from scratch, aiming to revolutionize the genomics field. They are seeking a Bioinformatics Scientist to develop computational solutions for processing NGS data and designing novel sequence variants, while collaborating with a multidisciplinary team.
Responsibilities:
- Development of software solutions for storing, querying, processing, and visualizing biological data and sequences.
- Utilizing data science techniques and frameworks, including modeling (e.g., entity relationship diagrams), analysis (e.g., pandas, numpy, scikit-learn), and visualization (e.g., matplotlib, plotly).
- Contribute to the development of traditional as well as AI/ML-based solutions to design novel antibody sequences using LLMs.
- Analyze output from wet lab assays (expression, binding data, developability assessment, etc.) and process large, high-content datasets to produce data reports and automated analysis pipelines.
- Collaborate with internal members throughout all phases of R&D workflows, analyzing bioinformatics requirements, addressing them promptly, and providing technical support.
- Follow and establish software development best practices, including requirement gathering, conceptualization, coding, testing, deployment, maintenance, and code versioning/management.
Qualifications:
Required:
- Master's or PhD in Bioinformatics, Computational Biology, or related scientific discipline with 0-1 years of related experience.
- Strong foundational coding skills in Python.
- Demonstrated experience in antibody and/or other therapeutic proteins for discovery and engineering applications.
- Understanding of LLMs and/or neural network models for sequence design.
- Experience in analyzing biological datasets (e.g., NGS), visualizing results (e.g., interactive plots), and working with common file formats (e.g., FASTA, FASTQ).
- Basic understanding of cloud computing, workflow management systems, and CI/CD pipelines.
- Interest in developing web applications (e.g., Django, React) and utilizing database systems (e.g., PostgreSQL).
Preferred:
- Industry experience preferred.
Company:
Twist Bioscience is a biotechnology company offering synthetic DNA solutions, gene synthesis, and variant libraries. Founded in 2013, headquartered in San Francisco, CA, with 501-1000 employees. The company is publicly traded and has a history of H1B sponsorships.
Seniority level
- Entry level
Employment type
- Full-time
Job function
- Software Development
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Inferred benefits
Medical insurance, Vision insurance, 401(k).
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Location and salary info: San Francisco, CA, $150,000-$250,000, posted 10 months ago.
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