Virginia Department of Human Resource Management
Post-Doctoral Research Fellow, SOM, Stravitz-Sanyal Institute for...
Virginia Department of Human Resource Management - Richmond, Virginia, United States, 23220
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Post-Doctoral Research Fellow, SOM, Stravitz-Sanyal Institute for Liver Disease
Virginia Commonwealth University (VCU) School of Medicine is a premier academic medical center located in the heart of Richmond. Accounting for almost half of VCU's sponsored research, the School of Medicine is internationally recognized for patient care and education. All full-time university staff are eligible for VCU's generous benefits package that includes competitive health benefits, paid annual and holiday leave, retirement planning and savings options, tax-deferred annuity and cash match programs, Virginia Retirement System (VRS), professional development & certifications, tuition waiver, parental leave, caregiving leave and community service leave. The Stravitz-Sanyal Institute for Liver Disease and Metabolic Health (SSI) is recruiting a highly motivated postdoctoral fellow to join the Saul Karpen lab. The research arc of the Karpen lab focuses upon wet bench validations of etiologic gene discoveries and therapeutic target identification for rare childhood liver diseases. Recent explorations have focused upon discovering etiologic causes of the # 1 reason to transplant a liver during childhood-biliary atresia. The successful candidate will develop and apply research methods to analyzing a first genetic model of biliary atresia, the Pkd1l1 conditional KO mouse, including evaluations of therapeutic efficacy. Qualifications: PhD in Molecular or Cellular Biology, Biochemistry, Physiology or other relevant discipline. Experience with mouse models of metabolic disease or hepatobiliary disease. Experience with cell signaling and developmental biology. Experience with membrane biology and bile acid signaling are strongly considered. Experience with primary cell culture, epithelial cells or organoids, with isolation and culture of mouse cholangiocytes a major prioritization. Experience with standard DNA, RNA and Protein analytics (imaging and immunoblotting). Experience with advanced confocal imaging and in vivo imaging are encouraged. Creativity and substantial evidence of productive publication history. Independence, scientific rigor and critical thinking. Additional Information: Position Details: Department: SSI Employment Type: PD - Post Doc, Commensurate with experience based on NIH postdoc scale Restricted Status: Yes FTE: 100 Exemption Status: Exempt Virginia Commonwealth University (VCU) School of Medicine is a premier academic medical center located in the heart of Richmond. Accounting for almost half of VCU's sponsored research, the School of Medicine is internationally recognized for patient care and education. Virginia Commonwealth University is an equal opportunity, affirmative action university providing access to education and employment without regard to race, color, religion, national origin, age, sex, political affiliation, veteran status, genetic information, sexual orientation, gender identity, gender expression, or disability.
Virginia Commonwealth University (VCU) School of Medicine is a premier academic medical center located in the heart of Richmond. Accounting for almost half of VCU's sponsored research, the School of Medicine is internationally recognized for patient care and education. All full-time university staff are eligible for VCU's generous benefits package that includes competitive health benefits, paid annual and holiday leave, retirement planning and savings options, tax-deferred annuity and cash match programs, Virginia Retirement System (VRS), professional development & certifications, tuition waiver, parental leave, caregiving leave and community service leave. The Stravitz-Sanyal Institute for Liver Disease and Metabolic Health (SSI) is recruiting a highly motivated postdoctoral fellow to join the Saul Karpen lab. The research arc of the Karpen lab focuses upon wet bench validations of etiologic gene discoveries and therapeutic target identification for rare childhood liver diseases. Recent explorations have focused upon discovering etiologic causes of the # 1 reason to transplant a liver during childhood-biliary atresia. The successful candidate will develop and apply research methods to analyzing a first genetic model of biliary atresia, the Pkd1l1 conditional KO mouse, including evaluations of therapeutic efficacy. Qualifications: PhD in Molecular or Cellular Biology, Biochemistry, Physiology or other relevant discipline. Experience with mouse models of metabolic disease or hepatobiliary disease. Experience with cell signaling and developmental biology. Experience with membrane biology and bile acid signaling are strongly considered. Experience with primary cell culture, epithelial cells or organoids, with isolation and culture of mouse cholangiocytes a major prioritization. Experience with standard DNA, RNA and Protein analytics (imaging and immunoblotting). Experience with advanced confocal imaging and in vivo imaging are encouraged. Creativity and substantial evidence of productive publication history. Independence, scientific rigor and critical thinking. Additional Information: Position Details: Department: SSI Employment Type: PD - Post Doc, Commensurate with experience based on NIH postdoc scale Restricted Status: Yes FTE: 100 Exemption Status: Exempt Virginia Commonwealth University (VCU) School of Medicine is a premier academic medical center located in the heart of Richmond. Accounting for almost half of VCU's sponsored research, the School of Medicine is internationally recognized for patient care and education. Virginia Commonwealth University is an equal opportunity, affirmative action university providing access to education and employment without regard to race, color, religion, national origin, age, sex, political affiliation, veteran status, genetic information, sexual orientation, gender identity, gender expression, or disability.