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IRIS Kinetics

Associate Scientist, Assay Development (Proteins & Biophysics)

IRIS Kinetics, Boston

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VP of Product & Strategy | Driving Next-Gen Biosensor Innovation

About IRIS Kinetics

At IRIS Kinetics, we are pioneering next-generation label-free biosensing platforms to transform diagnostics and life sciences. Our technology enables ultra-sensitive, real-time detection of biomolecular interactions, powering both research and clinical applications. We are seeking a highly motivated Associate Scientist to join our growing R&D team and help drive assay development for proteins, antibodies, nucleic acids, and small molecules.

Responsibilities

As an Associate Scientist, you will play a key role bridging senior scientists and junior research associates, contributing to assay development while supporting day-to-day lab operations. You will:

  • Design, execute, and analyze experiments for protein, antibody, nucleic acid, and small-molecule interactions.
  • Design, implement, and evaluate surface functionalization and immobilization chemistries for biosensor applications.
  • Optimize and characterize materials and surface chemistries to enhance sensor performance and reproducibility.
  • Independently perform common wet lab techniques (pipetting, aliquoting, titration, pH measurements, reagent prep) and troubleshoot issues as they arise.
  • Develop and optimize immunoassays, including ELISA, for sensitivity and reproducibility.
  • Apply biophysical methods such as BLI (Bio-Layer Interferometry) or SPR (Surface Plasmon Resonance) for kinetic characterization of biomolecular interactions.
  • Support development of assays tailored to the IRIS platform and contribute to validation studies.
  • Train and mentor Research Associates on lab techniques, experimental design, and best practices.
  • Maintain accurate and thorough documentation of experimental protocols, results, and analysis.
  • Contribute to lab organization, workflow efficiency, and maintaining a collaborative team environment.
  • Stay informed about emerging scientific trends and technologies to integrate novel approaches into research activities.
  • Adhere to laboratory safety standards and contribute to the development of Standard Operating Procedures (SOPs).

Qualifications

Required

  • B.S. or M.S. in Biochemistry, Molecular Biology, Biophysics, Biomedical Engineering, or related field.
  • 3–5 years of hands-on industry experience in an assay development, protein science, or biophysics-focused lab.
  • Strong proficiency in wet lab techniques (pipetting, buffer prep, titrations, pH measurement, instrument handling).
  • Demonstrated expertise in protein/antibody handling and immunoassay development (ELISA or similar).
  • Solid understanding of biomolecular interaction kinetics (binding affinity, on/off rates, etc.).
  • Ability to work independently with minimal supervision while collaborating in a team.

Preferred

  • Experience with BLI (ex. Octet) , SPR (ex. Biacore) , or other label-free kinetic analysis platforms.
  • Familiarity with antibody engineering, conjugation, or small-molecule binding studies.
  • Prior mentoring or training of junior scientists.
  • Excellent problem-solving, organization, and communication skills.

What We Offer

  • Opportunity to join a fast-growing startup developing breakthrough diagnostics technology.
  • Collaborative and dynamic work environment with room for growth into Scientist roles.
  • Competitive salary and benefits.

Seniority level

  • Seniority level

    Mid-Senior level

Employment type

  • Employment type

    Full-time

Job function

  • Job function

    Research, Analyst, and Information Technology

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