Use Your Power For Purpose
You will have a profound impact on improving patients' lives by ensuring our evidence is scientifically robust and providing unbiased, medically essential expertise. Your role is vital in connecting sound scientific evidence with practical medical insights to enhance health and treatment outcomes. By bridging data gaps and empowering healthcare decisions regarding the safe and appropriate use of medicines, you will contribute significantly to patient care and treatment efficacy.
In addition to professional challenge, we offer a culture that supports and encourages ideas, and recognizes individual contribution.
Role Summary
Develops model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision-making, in collaboration with partners.
Conducts and reports quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development.
Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety.
Support and/or develop pharmacometrics tools, automation workflows, software, and related business processes.
Role Responsibilities
- Provide support in the development of quantitative methodology, pharmacometrics tools, software, hardware, and/or related business processes.
- With guidance, provide MIDD expertise on multidisciplinary development teams, working closely with clinical pharmacologists, clinicians, and statisticians to create MIDD plans that include assessments of a drug's efficacy, safety, and commercial viability.
- Responsible for the planning and execution of relevant quantitative analyses.
- Prepare formal presentations and written reports to Pfizer standards.
- Contribute to regulatory documents.
- Have a good understanding of literature, government guidelines, and internal guidance as relates to pharmacometrics and MIDD.
- Contribute to the development or improvement of our tools, processes and methodology.
Basic Qualifications
- PhD or equivalent degree with strong quantitative skills.
- Three years or more of experience in a quantitative field.
- Expertise in analysis and programming software.
- Experience in pharmacometric analyses.
- Good communication skills.
- Drug development and/or regulatory experience.
- Publications in relevant discipline.
- Good understanding of Pharmacokinetics, Pharmacodynamics and Statistical Principles.
- Demonstrates a breadth of diverse leadership experiences and capabilities.
Preferred Qualifications
- Experience using Nonmem, R and/or PsN softwares is preferred.
- Candidates from alternative backgrounds will be considered if they can demonstrate relevant experience and expertise.
We encourage applicants from different disciplines including clinical pharmacology, engineering, biostatistics, medicine, biology, etc.
Organizational Relationships
- Reports to Pharmacometrics Group Leader within the line organization of Pharmacometrics and Systems Pharmacology.
- Matrixed relationships particularly with Clinical Pharmacology Leads, Clinicians, Statisticians, and colleagues from Programming groups and other groups as required.
Physical/Mental Requirements
Sitting, ability to perform complex data analyses.
Work Location Assignment: Hybrid.
The annual base salary for this position ranges from $135,100.00 to $225,100.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.
Relocation assistance may be available based on business needs and/or eligibility.