Overview
Senior Scientist, Analytical Development at Lyell Immunopharma. The Senior Scientist will be responsible for leading development of flow cytometry–based assays for release and characterization of engineered T-cell products and analytics for process understanding. The role includes leading a group within Analytical Development, mentoring scientists, hands-on assay development, and driving projects in close collaboration across TechOps and research.
Responsibilities
- Design, develop, execute, and document flow cytometry analytical methods for release testing and to study processes for production of T cell therapies
- Critically analyze and interpret complex data to draw appropriate conclusions
- Support product characterization activities, including comparability assessments in support of product lifecycle management
- Act as a subject matter expert in providing analytical and data interpretation both internally and externally
- Partner in the transfer of qualified assays to QC, and support assay validation and investigations
- Complete assignments that have an impact on functional goals
- Develop and deliver scientific presentations, prepare technical reports, participate in project teams, and contribute to regulatory filings as needed
- Participate in the evaluation of new analytical technologies and their implementation
- Revise, review, and author assay standard operating procedures
- Contribute to building a culture of continuous learning, improvement, and innovation, and encourage team members to expand their technical skill base
Education
- Must have a PhD in cell biology, immunology or related field with at least six years’ relevant industry experience or an MS with at least 11 years of relevant industry experience
Preferred Experience & Skills
- A minimum of 10 years of extensive experience in developing flow-based assays
- Well versed with flow cytometers such as MACSQuant, BD Lyric and Cytek Aurora
- Experience in cytotoxicity assays, flow cytometry, cytokine release assays, cell counting and other applicable methods
- Prior experience of leading and managing scientific teams
- Experience in analytical development, cGMP QC testing and implementation of new technologies in a regulated environment
- Experience with assessment of new technologies in a fast-paced, cross-functional setting
- Prior experience in cell therapy development preferred
- Excellent oral and written communication skills; ability to work independently and collaboratively across cross-functional teams
- Ability to prioritize workflow, meet deadlines and balance competing priorities
- Strong analytical skills and technical expertise
Compensation and Benefits
The salary range for this position is $180,000 to $210,000 annually, with the opportunity to earn an annual bonus. The salary range is an estimate; actual salary may vary based on Lyell’s compensation practices and the applicant’s qualifications and experience. Employees are eligible to participate in Lyell’s Equity Incentive Plan. Lyell offers extensive benefits including medical, dental, vision, FSA, Life and AD&D Insurance, STD & LTD, ESPP, 401(k) with company match, transit benefits, cell phone reimbursement, and additional options. Paid time off includes 18 days of vacation, 9 days of sick leave, 8 holidays plus a floating holiday, with summer and winter office shutdowns.
Equal Opportunity
Lyell is an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, disability, medical condition, marital status, veteran status, or any other characteristics protected by applicable laws.
Eligibility and Application
If you’re interested and think you could fit, please apply. Referrals increase your chances of interviewing at Lyell Immunopharma.
Job Details
- Seniority level: Mid-Senior level
- Employment type: Full-time
- Job function: Research, Analyst, and Information Technology