Regeneron Pharmaceuticals
Overview
Scientist (Seattle, WA)
– Regeneron Pharmaceuticals, Inc. seeks a Scientist (Seattle, WA) to assist with researching literature and market landscape to identify potential therapeutic targets and associated product concepts. Devise experimental plans to validate identified targets. Generate libraries of immunotherapeutic proteins and perform assay-based screening to identify promising hits. Perform standard T cell characterization assays, including cocultures to evaluate antigen specificity, target cell cytotoxicity, and T cell proliferation. Analyze high-throughput data using bioinformatics workflows in R and adjust parameters as necessary. Employ state-of-the-art automation instruments and collaborate with automation scientists to refine protocols. Provide guidance and mentorship to junior interns. Interpret and present data at working groups to help the broader department make data-driven decisions. Travel required: 4% domestic. Salary range:
$79,100.00 – $129,100.00 per year Job Requirements
Requires a Bachelor’s degree in Cell and Molecular Biology, Immunology, Biochemistry, Biology or related field and 3 years of pharmaceutical/biotech industry research experience. Employer will also accept a Master’s degree in the mentioned fields and 1 year of specified experience. Experience with: cell signaling pathways, protein engineering and cancer immunotherapies. Molecular biology techniques such as DNA construct design and cloning, including large-scale library cloning and quality assessment using Next-Generation Sequencing. Mammalian cell culture and cell line engineering by CRISPR-Cas9 genome editing. Common laboratory automation platforms, such as Hamilton and Integra Assist Plus. Multicolor analytical flow cytometry, as well as fluorescence activated cell sorting (FACS). Common data analysis software including FlowJo and GraphPad Prism. Bioinformatic analysis of sequence data using R and/or Python. Ability to drive results in multiple projects simultaneously and plan and organize work activities to meet schedules and deadlines. Ability to interpret results and present them effectively in a variety of team settings and contribute constructively to scientific discussions. Must have scientific publications in the pharmaceutical/biotech industry research field. Travel requirement: 4% domestic. Equal Opportunity
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of a protected class, sexual orientation, disability, genetic information, familial status, or any other protected characteristic in accordance with applicable laws and regulations. Reasonable accommodation will be provided to qualified applicants with known disabilities or chronic illnesses, unless the accommodation would impose undue hardship on the operation of the business. Please note that certain background checks will form part of the recruitment process and will be conducted in accordance with the law of the country where the position is based. To apply for this position, please visit Regeneron’s careers site and reference code: R40083. This role may include details on total rewards and benefits as described on the company site.
#J-18808-Ljbffr
Scientist (Seattle, WA)
– Regeneron Pharmaceuticals, Inc. seeks a Scientist (Seattle, WA) to assist with researching literature and market landscape to identify potential therapeutic targets and associated product concepts. Devise experimental plans to validate identified targets. Generate libraries of immunotherapeutic proteins and perform assay-based screening to identify promising hits. Perform standard T cell characterization assays, including cocultures to evaluate antigen specificity, target cell cytotoxicity, and T cell proliferation. Analyze high-throughput data using bioinformatics workflows in R and adjust parameters as necessary. Employ state-of-the-art automation instruments and collaborate with automation scientists to refine protocols. Provide guidance and mentorship to junior interns. Interpret and present data at working groups to help the broader department make data-driven decisions. Travel required: 4% domestic. Salary range:
$79,100.00 – $129,100.00 per year Job Requirements
Requires a Bachelor’s degree in Cell and Molecular Biology, Immunology, Biochemistry, Biology or related field and 3 years of pharmaceutical/biotech industry research experience. Employer will also accept a Master’s degree in the mentioned fields and 1 year of specified experience. Experience with: cell signaling pathways, protein engineering and cancer immunotherapies. Molecular biology techniques such as DNA construct design and cloning, including large-scale library cloning and quality assessment using Next-Generation Sequencing. Mammalian cell culture and cell line engineering by CRISPR-Cas9 genome editing. Common laboratory automation platforms, such as Hamilton and Integra Assist Plus. Multicolor analytical flow cytometry, as well as fluorescence activated cell sorting (FACS). Common data analysis software including FlowJo and GraphPad Prism. Bioinformatic analysis of sequence data using R and/or Python. Ability to drive results in multiple projects simultaneously and plan and organize work activities to meet schedules and deadlines. Ability to interpret results and present them effectively in a variety of team settings and contribute constructively to scientific discussions. Must have scientific publications in the pharmaceutical/biotech industry research field. Travel requirement: 4% domestic. Equal Opportunity
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of a protected class, sexual orientation, disability, genetic information, familial status, or any other protected characteristic in accordance with applicable laws and regulations. Reasonable accommodation will be provided to qualified applicants with known disabilities or chronic illnesses, unless the accommodation would impose undue hardship on the operation of the business. Please note that certain background checks will form part of the recruitment process and will be conducted in accordance with the law of the country where the position is based. To apply for this position, please visit Regeneron’s careers site and reference code: R40083. This role may include details on total rewards and benefits as described on the company site.
#J-18808-Ljbffr