My Next Stage
Principal Scientist, Cardiovascular In Vivo Pharmacology
My Next Stage, Princeton, New Jersey, us, 08543
Working with Us
Challenging. Meaningful. Life-changing.
These aren’t words typically associated with a job, yet Bristol Myers Squibb offers work that transforms lives of patients and careers of colleagues. Opportunities to grow and thrive exist across teams, with a focus on meaningful contributions and impactful science. Bristol Myers Squibb recognizes balance and flexibility in our work environment. We offer competitive benefits, services and programs to support employees’ goals at work and in personal life. Careful consideration of location and program details can be found on our careers site. The Immunology and Cardiovascular Thematic Research Center (ICV TRC)
at BMS is a fundamental research unit delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow using cutting-edge science and BMS’s internal invention engine across modalities including small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and more. Position Summary
We seek a cardiovascular biologist with a track record of using molecular and cellular tools and animal models to understand the effects of mutation on cardiac structure and function and response to intervention. The successful candidate will apply knowledge of cardiovascular physiology to identify and validate cardiac targets, establish pharmacodynamic endpoints in vivo and in vitro to enable drug discovery, elucidate structural-functional pathophysiology, and direct ex vivo, microscopic, and/or biochemical characterization of samples. This is a lab-based role with time spent reviewing programs and targets, analyzing data, presenting results to stakeholders and leadership, and serving as a team representative. Position Responsibilities
Perform in vivo and in vitro/ex vivo studies to define pharmacodynamic/pharmacokinetic relationships and to characterize and develop disease models relevant to programs and treatment responses Lead studies to completion, including directing analysis of samples internally or through management of CRO activities Evaluate programs critically and present findings and recommendations to leadership Identify opportunities for protocol improvement and develop new experimental protocols Apply technical knowledge to make in-life experimental adjustments when necessary Document and review experimental approaches, modify as needed, and present data in a timely manner Collaborate with cross-functional teams by providing timely and actionable study results Provide hands-on training and guidance to develop team members or direct reports May serve as a functional area lead for drug discovery programs independently or with leadership support Contribute to and author reports, abstracts, and publications Write protocols for IACUC approval and work with IACUC committees Experience
Basic Qualifications
Bachelor’s Degree — 8+ years of academic and/or industry experience Or Master’s Degree — 6+ years of academic and/or industry experience Or Ph.D. or equivalent advanced degree in the Life Sciences — 4+ years of academic and/or industry experience Preferred Qualifications
Ph.D. in Physiology, Pharmacology, Biology, Biochemistry, or related field with 4+ years of relevant industry experience; or PharmD/DVM/MD with strong basic science/drug discovery contributions; or MS with 6+ years of relevant industry experience Strong understanding of cardiovascular physiology and modern methodologies Hands-on experience handling rodents; echocardiography knowledge and practice is preferred, with hands-on rodent echocardiography strongly preferred Understanding of cardiovascular hemodynamics, with hands-on invasive hemodynamics experience preferred Knowledge of 3Rs principles in designing and initiating animal studies Highly motivated, team-oriented, and capable of working in a multidisciplinary environment Excellent laboratory, organizational and time management skills; detail-oriented and reliable Ability to work self-motivated and collaboratively in a matrixed team LI-Onsite If a role intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview
Princeton, NJ, US: $135,800 - $164,563. Starting compensation ranges are for full-time employment and may include incentive cash and stock opportunities (eligibility applies). Final compensation is based on demonstrated experience. Benefits vary by location and role. For more information, visit the benefits section on our careers site. Benefits may include medical, dental, vision, 401(k), disability and life insurance, paid holidays, vacation, volunteer days, parental and caregiver leave, adoption and surrogacy support, fertility benefits, reimbursement programs, and other perks. Uniquely Interesting Work, Life-changing Careers
Our vision is Transforming patients’ lives through science. Each employee contributes to work that goes beyond ordinary, with values of passion, innovation, urgency, accountability, inclusion and integrity guiding our actions. On-site Protocol Site-essential roles require 100% onsite; site-by-design roles may offer hybrid work with at least 50% onsite. Field-based and remote roles may require travel to visit customers, patients, or partners as directed. BMS is committed to accessibility and reasonable accommodations in recruitment and employment. If you require accommodations in completing this application or during recruitment, contact adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility for our Equal Employment Opportunity statement. BMS recommends vaccination against Covid-19 and boosters as part of well-being guidelines. Employment decisions consider applicable laws and individual qualifications. If you live in or work from Los Angeles County, please review additional information at careers.bms.com/california-residents/ Data collected in relation to role applications will be processed per applicable data privacy policies.
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Challenging. Meaningful. Life-changing.
These aren’t words typically associated with a job, yet Bristol Myers Squibb offers work that transforms lives of patients and careers of colleagues. Opportunities to grow and thrive exist across teams, with a focus on meaningful contributions and impactful science. Bristol Myers Squibb recognizes balance and flexibility in our work environment. We offer competitive benefits, services and programs to support employees’ goals at work and in personal life. Careful consideration of location and program details can be found on our careers site. The Immunology and Cardiovascular Thematic Research Center (ICV TRC)
at BMS is a fundamental research unit delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow using cutting-edge science and BMS’s internal invention engine across modalities including small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and more. Position Summary
We seek a cardiovascular biologist with a track record of using molecular and cellular tools and animal models to understand the effects of mutation on cardiac structure and function and response to intervention. The successful candidate will apply knowledge of cardiovascular physiology to identify and validate cardiac targets, establish pharmacodynamic endpoints in vivo and in vitro to enable drug discovery, elucidate structural-functional pathophysiology, and direct ex vivo, microscopic, and/or biochemical characterization of samples. This is a lab-based role with time spent reviewing programs and targets, analyzing data, presenting results to stakeholders and leadership, and serving as a team representative. Position Responsibilities
Perform in vivo and in vitro/ex vivo studies to define pharmacodynamic/pharmacokinetic relationships and to characterize and develop disease models relevant to programs and treatment responses Lead studies to completion, including directing analysis of samples internally or through management of CRO activities Evaluate programs critically and present findings and recommendations to leadership Identify opportunities for protocol improvement and develop new experimental protocols Apply technical knowledge to make in-life experimental adjustments when necessary Document and review experimental approaches, modify as needed, and present data in a timely manner Collaborate with cross-functional teams by providing timely and actionable study results Provide hands-on training and guidance to develop team members or direct reports May serve as a functional area lead for drug discovery programs independently or with leadership support Contribute to and author reports, abstracts, and publications Write protocols for IACUC approval and work with IACUC committees Experience
Basic Qualifications
Bachelor’s Degree — 8+ years of academic and/or industry experience Or Master’s Degree — 6+ years of academic and/or industry experience Or Ph.D. or equivalent advanced degree in the Life Sciences — 4+ years of academic and/or industry experience Preferred Qualifications
Ph.D. in Physiology, Pharmacology, Biology, Biochemistry, or related field with 4+ years of relevant industry experience; or PharmD/DVM/MD with strong basic science/drug discovery contributions; or MS with 6+ years of relevant industry experience Strong understanding of cardiovascular physiology and modern methodologies Hands-on experience handling rodents; echocardiography knowledge and practice is preferred, with hands-on rodent echocardiography strongly preferred Understanding of cardiovascular hemodynamics, with hands-on invasive hemodynamics experience preferred Knowledge of 3Rs principles in designing and initiating animal studies Highly motivated, team-oriented, and capable of working in a multidisciplinary environment Excellent laboratory, organizational and time management skills; detail-oriented and reliable Ability to work self-motivated and collaboratively in a matrixed team LI-Onsite If a role intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview
Princeton, NJ, US: $135,800 - $164,563. Starting compensation ranges are for full-time employment and may include incentive cash and stock opportunities (eligibility applies). Final compensation is based on demonstrated experience. Benefits vary by location and role. For more information, visit the benefits section on our careers site. Benefits may include medical, dental, vision, 401(k), disability and life insurance, paid holidays, vacation, volunteer days, parental and caregiver leave, adoption and surrogacy support, fertility benefits, reimbursement programs, and other perks. Uniquely Interesting Work, Life-changing Careers
Our vision is Transforming patients’ lives through science. Each employee contributes to work that goes beyond ordinary, with values of passion, innovation, urgency, accountability, inclusion and integrity guiding our actions. On-site Protocol Site-essential roles require 100% onsite; site-by-design roles may offer hybrid work with at least 50% onsite. Field-based and remote roles may require travel to visit customers, patients, or partners as directed. BMS is committed to accessibility and reasonable accommodations in recruitment and employment. If you require accommodations in completing this application or during recruitment, contact adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility for our Equal Employment Opportunity statement. BMS recommends vaccination against Covid-19 and boosters as part of well-being guidelines. Employment decisions consider applicable laws and individual qualifications. If you live in or work from Los Angeles County, please review additional information at careers.bms.com/california-residents/ Data collected in relation to role applications will be processed per applicable data privacy policies.
#J-18808-Ljbffr