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Overview
Lead Security Architect role in a forward-looking cybersecurity team. Design and implement secure, scalable architectures across cloud, containerized, and on-premises environments. Shape security strategy for modern platforms across AWS, networks, OT, and SaaS platforms. Develop Security Reference Architectures to guide consistent, secure technology adoption. Support secure integration of SaaS platforms while aligning with enterprise security standards. Collaborate with cross-functional teams to embed security across the technology stack. Hands-on experience with security automation and proficiency in Python or similar scripting to drive operational efficiency. Primary Responsibilities
Lead the development and implementation of enterprise-wide security architecture strategies and frameworks Develop and maintain threat models and security reference architectures for AWS and on‑premises environments with emphasis on Zero Trust, IAM, encryption, secure access controls, SIEM, and XDR Partner with Engineering, DevOps, IT, and Compliance teams to embed secure-by-default principles into infrastructure and applications Collaborate with DevOps and engineering teams to embed security into CI/CD workflows and Infrastructure-as-Code processes Establish and enforce security practices in containerized environments (e.g., EKS, ECS) and AI-enabled applications, including workload protection, runtime monitoring, and secrets management Support the secure design, development, and deployment of AI/ML solutions and data pipelines with robust controls around model access, training data, and infrastructure Champion security automation and playbooks using tools such as Python, Lambda, Terraform, and related technologies to streamline security testing, threat detection, and remediation workflows Evaluate and recommend security tools, platforms, and automation approaches aligned with business goals and security requirements Perform architectural risk assessments for new and existing systems and provide actionable guidance and mitigation strategies Work with Incident Response teams to ensure security architecture aligns with current and emerging threat landscapes Participate in design reviews, conduct threat modeling exercises, and contribute to architecture governance and decision-making Influence security policies and standards to align with industry best practices and regulatory frameworks (e.g., HIPAA, NIST, CISA, FDA) Stay current on industry trends, emerging threats (including AI-driven threats), and technologies to continuously enhance security posture Serve as a trusted technical and strategic advisor to executive leadership on security architecture, technology risks, and mitigation strategies Mentor and provide guidance to security engineers and developers on secure design principles and architectural best practices Qualifications
Bachelor1s degree in Computer Science, Information Security, Engineering, or related field Master1s degree in Computer Science with a focus on Information Security or related discipline is strongly preferred Minimum of 12 years of progressive cybersecurity experience, including at least 5 years in security architecture or senior-level engineering Deep experience in threat modeling, design, PoC, and implementing large-scale enterprise solutions (Healthcare or financial sectors preferred) Proven ability to design and implement security controls aligned with HIPAA, NIST, and CIS Extensive hands-on experience in AWS cloud security and network security, with knowledge of Zero Trust, data protection, and AppSec Strong understanding of IAM systems and data protection, including platforms like Okta, SailPoint, VDI, and Active Directory Expert experience with SIEM, XDR, and cloud-threat detection tools Expert experience in web application security, OWASP, API security, and secure design and testing Hands-on experience with security automation and proficiency in Python, Lambda, Terraform, or comparable IaC tools Industry certifications such as CISSP, CCSP, AWS Certified Security – Specialty, AWS Certified Solutions Architect – Professional, or AWS Certified Advanced Networking – Specialty (or equivalent) Knowledge, Skills, and Abilities
Excellent written and verbal communication skills, able to translate complex security concepts for technical and non-technical audiences Ability to influence stakeholders and drive alignment across multiple teams Strategic thinker with a passion for security innovation and building scalable defenses The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate. Remote USA: $172,400—$215,450 USD. Our Opportunity
Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women9s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions. The Natera team consists of statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers, and other professionals from world-class institutions. What We Offer
Competitive benefits, including comprehensive medical, dental, vision, life and dependent plans. Free testing for employees and their immediate families, fertility care benefits, baby bonding leave, 401k, commuter benefits, and an employee referral program. For more information, visit the
site is not allowed here . Please ignore this placeholder text. EEO Notice
Natera is an Equal Opportunity Employer. We are committed to a diverse and inclusive workplace and welcome people of different backgrounds, experiences, abilities, and perspectives. All qualified applicants will be considered without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, please review important information for California residents.
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Lead Security Architect role in a forward-looking cybersecurity team. Design and implement secure, scalable architectures across cloud, containerized, and on-premises environments. Shape security strategy for modern platforms across AWS, networks, OT, and SaaS platforms. Develop Security Reference Architectures to guide consistent, secure technology adoption. Support secure integration of SaaS platforms while aligning with enterprise security standards. Collaborate with cross-functional teams to embed security across the technology stack. Hands-on experience with security automation and proficiency in Python or similar scripting to drive operational efficiency. Primary Responsibilities
Lead the development and implementation of enterprise-wide security architecture strategies and frameworks Develop and maintain threat models and security reference architectures for AWS and on‑premises environments with emphasis on Zero Trust, IAM, encryption, secure access controls, SIEM, and XDR Partner with Engineering, DevOps, IT, and Compliance teams to embed secure-by-default principles into infrastructure and applications Collaborate with DevOps and engineering teams to embed security into CI/CD workflows and Infrastructure-as-Code processes Establish and enforce security practices in containerized environments (e.g., EKS, ECS) and AI-enabled applications, including workload protection, runtime monitoring, and secrets management Support the secure design, development, and deployment of AI/ML solutions and data pipelines with robust controls around model access, training data, and infrastructure Champion security automation and playbooks using tools such as Python, Lambda, Terraform, and related technologies to streamline security testing, threat detection, and remediation workflows Evaluate and recommend security tools, platforms, and automation approaches aligned with business goals and security requirements Perform architectural risk assessments for new and existing systems and provide actionable guidance and mitigation strategies Work with Incident Response teams to ensure security architecture aligns with current and emerging threat landscapes Participate in design reviews, conduct threat modeling exercises, and contribute to architecture governance and decision-making Influence security policies and standards to align with industry best practices and regulatory frameworks (e.g., HIPAA, NIST, CISA, FDA) Stay current on industry trends, emerging threats (including AI-driven threats), and technologies to continuously enhance security posture Serve as a trusted technical and strategic advisor to executive leadership on security architecture, technology risks, and mitigation strategies Mentor and provide guidance to security engineers and developers on secure design principles and architectural best practices Qualifications
Bachelor1s degree in Computer Science, Information Security, Engineering, or related field Master1s degree in Computer Science with a focus on Information Security or related discipline is strongly preferred Minimum of 12 years of progressive cybersecurity experience, including at least 5 years in security architecture or senior-level engineering Deep experience in threat modeling, design, PoC, and implementing large-scale enterprise solutions (Healthcare or financial sectors preferred) Proven ability to design and implement security controls aligned with HIPAA, NIST, and CIS Extensive hands-on experience in AWS cloud security and network security, with knowledge of Zero Trust, data protection, and AppSec Strong understanding of IAM systems and data protection, including platforms like Okta, SailPoint, VDI, and Active Directory Expert experience with SIEM, XDR, and cloud-threat detection tools Expert experience in web application security, OWASP, API security, and secure design and testing Hands-on experience with security automation and proficiency in Python, Lambda, Terraform, or comparable IaC tools Industry certifications such as CISSP, CCSP, AWS Certified Security – Specialty, AWS Certified Solutions Architect – Professional, or AWS Certified Advanced Networking – Specialty (or equivalent) Knowledge, Skills, and Abilities
Excellent written and verbal communication skills, able to translate complex security concepts for technical and non-technical audiences Ability to influence stakeholders and drive alignment across multiple teams Strategic thinker with a passion for security innovation and building scalable defenses The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate. Remote USA: $172,400—$215,450 USD. Our Opportunity
Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women9s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions. The Natera team consists of statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers, and other professionals from world-class institutions. What We Offer
Competitive benefits, including comprehensive medical, dental, vision, life and dependent plans. Free testing for employees and their immediate families, fertility care benefits, baby bonding leave, 401k, commuter benefits, and an employee referral program. For more information, visit the
site is not allowed here . Please ignore this placeholder text. EEO Notice
Natera is an Equal Opportunity Employer. We are committed to a diverse and inclusive workplace and welcome people of different backgrounds, experiences, abilities, and perspectives. All qualified applicants will be considered without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, please review important information for California residents.
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