Vivid Resourcing
Overview
Chief Medical Officer (CMO) Location:
Raleigh-Durham, NC (On-site presence required 3x per week) Company:
Preclinical-stage Oncology Biotech (SME) About the Company Our client is a dynamic and innovative small-to-medium enterprise (SME) located in the Raleigh-Durham Research Triangle, dedicated to developing breakthrough oncology therapies. Currently in the
preclinical stage , the company is building a pipeline of novel cancer treatments with the potential to address significant unmet medical needs. With strong scientific leadership and robust financial backing, they are looking to appoint a
Chief Medical Officer (CMO)
to drive clinical and medical strategy as they transition towards first-in-human studies. Role Overview
The CMO will serve as a key member of the executive leadership team, providing medical and clinical development expertise to guide the companys oncology programs from preclinical through clinical proof-of-concept. This individual will lead clinical strategy, oversee interactions with regulatory agencies, and help build the clinical development function. A strong on-site presence (3 days per week) is required to collaborate with scientific leadership and shape the companys future growth. Key Responsibilities
Define and execute the clinical development strategy for oncology assets as the company advances into first-in-human studies. Provide strategic medical input into translational and preclinical programs to ensure alignment with clinical endpoints and patient benefit. Serve as primary medical spokesperson for the company with internal stakeholders, external partners, and regulatory authorities. Lead and oversee all aspects of early clinical trial design, protocol development, and execution, including Phase I/II oncology studies. Establish and manage relationships with investigators, KOLs, CROs, and industry partners. Ensure compliance with all applicable regulatory requirements (FDA, EMA, etc.) and maintain high standards of patient safety and ethics. Build and lead the medical/clinical development team, including hiring and mentoring clinical scientists and medical directors as the pipeline progresses. Partner with the CEO, CSO, and Board of Directors to shape overall corporate strategy. Qualifications & Experience
MD or MD/PhD with board certification in oncology, hematology, or a closely related specialty. Significant experience in oncology drug development, ideally from
preclinical to early clinical stage . Demonstrated leadership in designing and executing early-stage clinical trials (Phase I/II). Previous CMO or senior clinical development leadership role at a biotech or pharma company (SME/start-up experience strongly preferred). Deep understanding of oncology biology, translational research, and regulatory pathways for innovative cancer therapeutics. Proven track record of engaging with FDA and other regulatory agencies. Excellent communication skills with the ability to represent the company externally and inspire confidence internally. Entrepreneurial mindset, collaborative leadership style, and ability to thrive in a fast-paced, resource-conscious SME environment. Why Join
Opportunity to shape the clinical strategy and medical vision of a growing oncology biotech at a critical inflection point. Work closely with world-class scientific leaders and play a pivotal role in translating cutting-edge research into transformative therapies. Competitive compensation package including equity participation. Vibrant and innovative work environment in the Research Triangle biotech hub. Seniority level
Executive Employment type
Full-time Job function
Science Industries
Pharmaceutical Manufacturing
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Chief Medical Officer (CMO) Location:
Raleigh-Durham, NC (On-site presence required 3x per week) Company:
Preclinical-stage Oncology Biotech (SME) About the Company Our client is a dynamic and innovative small-to-medium enterprise (SME) located in the Raleigh-Durham Research Triangle, dedicated to developing breakthrough oncology therapies. Currently in the
preclinical stage , the company is building a pipeline of novel cancer treatments with the potential to address significant unmet medical needs. With strong scientific leadership and robust financial backing, they are looking to appoint a
Chief Medical Officer (CMO)
to drive clinical and medical strategy as they transition towards first-in-human studies. Role Overview
The CMO will serve as a key member of the executive leadership team, providing medical and clinical development expertise to guide the companys oncology programs from preclinical through clinical proof-of-concept. This individual will lead clinical strategy, oversee interactions with regulatory agencies, and help build the clinical development function. A strong on-site presence (3 days per week) is required to collaborate with scientific leadership and shape the companys future growth. Key Responsibilities
Define and execute the clinical development strategy for oncology assets as the company advances into first-in-human studies. Provide strategic medical input into translational and preclinical programs to ensure alignment with clinical endpoints and patient benefit. Serve as primary medical spokesperson for the company with internal stakeholders, external partners, and regulatory authorities. Lead and oversee all aspects of early clinical trial design, protocol development, and execution, including Phase I/II oncology studies. Establish and manage relationships with investigators, KOLs, CROs, and industry partners. Ensure compliance with all applicable regulatory requirements (FDA, EMA, etc.) and maintain high standards of patient safety and ethics. Build and lead the medical/clinical development team, including hiring and mentoring clinical scientists and medical directors as the pipeline progresses. Partner with the CEO, CSO, and Board of Directors to shape overall corporate strategy. Qualifications & Experience
MD or MD/PhD with board certification in oncology, hematology, or a closely related specialty. Significant experience in oncology drug development, ideally from
preclinical to early clinical stage . Demonstrated leadership in designing and executing early-stage clinical trials (Phase I/II). Previous CMO or senior clinical development leadership role at a biotech or pharma company (SME/start-up experience strongly preferred). Deep understanding of oncology biology, translational research, and regulatory pathways for innovative cancer therapeutics. Proven track record of engaging with FDA and other regulatory agencies. Excellent communication skills with the ability to represent the company externally and inspire confidence internally. Entrepreneurial mindset, collaborative leadership style, and ability to thrive in a fast-paced, resource-conscious SME environment. Why Join
Opportunity to shape the clinical strategy and medical vision of a growing oncology biotech at a critical inflection point. Work closely with world-class scientific leaders and play a pivotal role in translating cutting-edge research into transformative therapies. Competitive compensation package including equity participation. Vibrant and innovative work environment in the Research Triangle biotech hub. Seniority level
Executive Employment type
Full-time Job function
Science Industries
Pharmaceutical Manufacturing
#J-18808-Ljbffr