Syneos Health, Inc.
Project Manager I – Cell & Gene Therapy (Sponsor-Dedicated/ Remote)
Syneos Health, Inc., Houston, Texas, United States
Overview
Project Manager I – Cell & Gene Therapy (Sponsor-Dedicated/ Remote) Updated:
September 8, 2025 Location:
USA-HI-Remote Job ID:
25101519 Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities. Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives. Discover what our 29,000 employees, across 110 countries already know: WORK HERE MATTERS EVERYWHERE Why Syneos Health We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program. We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people. We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong. Responsibilities
Project Manager I – Sponsor Dedicated (Cell & Gene Therapy) Location: USA Remote with occasional travel to Los Angeles area. Note: Strong preference given to hybrid candidates located near our sponsor’s Los Angeles office (near Westwood neighborhood/ UCLA campus) Role Summary
We are seeking a skilled and motivated
Project Manager I
to join our
sponsor-dedicated team
supporting high-impact
oncology and cell & gene therapy trials , including
CAR-T studies . In this role, you will work full-time on behalf of a leading biopharmaceutical sponsor while employed within a global CRO—offering the best of both worlds: sponsor collaboration and CRO resources. This position focuses on early-phase trial execution, operational oversight, and cross-functional coordination across global study teams. While remote work is supported, we
strongly prefer candidates located near our sponsor’s Los Angeles office
(near Westwood neighborhood/ UCLA campus )
to allow for periodic in-office collaboration and faster integration with the sponsor team. What You Will Do
Act as a
sponsor-facing project manager , ensuring the successful execution of assigned
CAR-T and gene therapy trials
from startup through closeout. Lead or support
study start-up, site activation, and enrollment , working closely with site monitors, regulatory teams, and contracts personnel. Serve as a key point of contact across internal (CRO) and sponsor teams, facilitating regular communications, status reporting, and governance updates. Coordinate with cross-functional stakeholders to ensure timelines, budgets, and milestones are met, particularly in
complex, high-touch studies . Track and manage
protocol compliance ,
CAPAs , and
site-level quality indicators ; support resolution of audit findings. Ensure
inspection readiness
and regulatory compliance by overseeing
TMF maintenance , data accuracy, and documentation completeness. Manage or contribute to the tracking of
low-stability endpoint samples
and IP-related processes, ensuring timely lab delivery and site support. Assist with
risk identification and mitigation planning , while continuously optimizing trial execution processes. Qualifications
2–4 years of clinical trial experience , preferably in a
CRO setting , with a focus on
oncology, rare disease, or gene-modified cell therapy trials .
Prior involvement in
CAR-T or other cell therapy studies
is highly desirable.
Strong familiarity with
GCP/ICH guidelines , FDA/EMA regulations, and inspection-readiness standards.
Experience working in
sponsor-dedicated or embedded roles
within a CRO is a plus.
Proficiency in clinical systems (e.g.,
CTMS, EDC, eTMF ) and project management tools.
Confident in
leading sponsor calls , presenting KPIs, and contributing to operational governance.
Bachelor’s degree in a relevant field (Life Sciences, Nursing, Pharmacy, etc.) or equivalent work experience.
Comfortable with remote work but agreeable to
occasional in-person collaboration in Los Angeles .
Why You Want to Work Here
Work sponsor-side, stay CRO-strong : This sponsor-dedicated role offers the visibility and strategic engagement of working directly with a biotech leader, while maintaining CRO support and infrastructure.
Advance life-saving research : Be a part of cutting-edge
cell and gene therapy trials , helping bring breakthrough therapies to patients faster.
Grow your career intentionally : Gain exposure to high-impact projects with opportunities to step up into larger roles and leadership paths.
Collaborate where it counts : Enjoy the flexibility of remote work with access to in-office opportunities that foster deeper team integration and mentorship.
Be mission-aligned : Work with a team that shares your urgency, attention to detail, and dedication to patients battling cancer and rare diseases.
Why Join Us?
This role offers the opportunity to do more than manage clinical trials — it’s a chance to be at the center of some of the most promising therapeutic advancements in the world. You’ll play a critical role in accelerating the development of treatments that could change patients’ lives forever. If you're looking to grow your career while making a real-world impact, we invite you to apply and join a mission that matters. At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements. Salary Range: The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role. Get to know Syneos Health
Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients. No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health. http://www.syneoshealth.com Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job. Summary We are seeking a skilled and motivated Project Manager I to join our sponsor-dedicated team supporting high-impact oncology and cell & gene therapy trials, including CAR-T studies. In this role, you will work full-time on behalf of a leading biopharmaceutical sponsor while employed within a global CRO—offering the best of both worlds: sponsor collaboration and CRO resources.This position focuses on early-phase trial execution, operational oversight, and cross-functional coordination across global study teams. While remote work is supported, we strongly prefer candidates located near our sponsor’s Los Angeles office to allow for periodic in-office collaboration and faster integration with the sponsor team. At Syneos Health, we are dedicated to building a diverse, inclusive and authentic workplace. If your pastexperience doesn’t align perfectly, we encourage you to apply anyway. At times, we take intoconsideration transferrable skills from previous roles. We also encourage you to join our Talent Network to stay connected to additional career opportunities. Discover what our 29,000 employees already know: work here matters everywhere. We work hard,and smart, all in the name of getting much-needed therapies to thosewho need them most. A career with Syneos Health means your everyday work improvespatients’ lives around the world. Selecting us as an employer secures a career inwhich you’re guaranteed to: Syneos Health (Nasdaq: SYNH) is a leading integrated biopharmaceutical solutionsorganization built to accelerate customer success. We translate unique clinical,medical affairs and commercial insights into outcomes to address modern marketrealities. Together we share insights, use the latest technologies and applyadvanced business practices to speed our customers’ delivery of importanttherapies to patients. We support a diverse, equitable and inclusive culture. Phone: 919 876 9300 Fax: 919 876 9360 Toll-Free: 866 462 7373 Syneos Health is an Equal Opportunity Employer. All qualified applicants will receiveconsideration for employment without regard to race, color, age, religion, marital status,ethnicity, national origin, sex, gender, gender identity, sexual orientation, protectedveteran status, disability or any other legally protected status and will not bediscriminated against. If you are an individual with a disability who requires reasonableaccommodation to complete any part of our application process, including the use of thiswebsite, please contact us at: Email: jobs@syneoshealth.com One of our staff members will workwith you to provide alternate means to submit your application.
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Project Manager I – Cell & Gene Therapy (Sponsor-Dedicated/ Remote) Updated:
September 8, 2025 Location:
USA-HI-Remote Job ID:
25101519 Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities. Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives. Discover what our 29,000 employees, across 110 countries already know: WORK HERE MATTERS EVERYWHERE Why Syneos Health We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program. We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people. We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong. Responsibilities
Project Manager I – Sponsor Dedicated (Cell & Gene Therapy) Location: USA Remote with occasional travel to Los Angeles area. Note: Strong preference given to hybrid candidates located near our sponsor’s Los Angeles office (near Westwood neighborhood/ UCLA campus) Role Summary
We are seeking a skilled and motivated
Project Manager I
to join our
sponsor-dedicated team
supporting high-impact
oncology and cell & gene therapy trials , including
CAR-T studies . In this role, you will work full-time on behalf of a leading biopharmaceutical sponsor while employed within a global CRO—offering the best of both worlds: sponsor collaboration and CRO resources. This position focuses on early-phase trial execution, operational oversight, and cross-functional coordination across global study teams. While remote work is supported, we
strongly prefer candidates located near our sponsor’s Los Angeles office
(near Westwood neighborhood/ UCLA campus )
to allow for periodic in-office collaboration and faster integration with the sponsor team. What You Will Do
Act as a
sponsor-facing project manager , ensuring the successful execution of assigned
CAR-T and gene therapy trials
from startup through closeout. Lead or support
study start-up, site activation, and enrollment , working closely with site monitors, regulatory teams, and contracts personnel. Serve as a key point of contact across internal (CRO) and sponsor teams, facilitating regular communications, status reporting, and governance updates. Coordinate with cross-functional stakeholders to ensure timelines, budgets, and milestones are met, particularly in
complex, high-touch studies . Track and manage
protocol compliance ,
CAPAs , and
site-level quality indicators ; support resolution of audit findings. Ensure
inspection readiness
and regulatory compliance by overseeing
TMF maintenance , data accuracy, and documentation completeness. Manage or contribute to the tracking of
low-stability endpoint samples
and IP-related processes, ensuring timely lab delivery and site support. Assist with
risk identification and mitigation planning , while continuously optimizing trial execution processes. Qualifications
2–4 years of clinical trial experience , preferably in a
CRO setting , with a focus on
oncology, rare disease, or gene-modified cell therapy trials .
Prior involvement in
CAR-T or other cell therapy studies
is highly desirable.
Strong familiarity with
GCP/ICH guidelines , FDA/EMA regulations, and inspection-readiness standards.
Experience working in
sponsor-dedicated or embedded roles
within a CRO is a plus.
Proficiency in clinical systems (e.g.,
CTMS, EDC, eTMF ) and project management tools.
Confident in
leading sponsor calls , presenting KPIs, and contributing to operational governance.
Bachelor’s degree in a relevant field (Life Sciences, Nursing, Pharmacy, etc.) or equivalent work experience.
Comfortable with remote work but agreeable to
occasional in-person collaboration in Los Angeles .
Why You Want to Work Here
Work sponsor-side, stay CRO-strong : This sponsor-dedicated role offers the visibility and strategic engagement of working directly with a biotech leader, while maintaining CRO support and infrastructure.
Advance life-saving research : Be a part of cutting-edge
cell and gene therapy trials , helping bring breakthrough therapies to patients faster.
Grow your career intentionally : Gain exposure to high-impact projects with opportunities to step up into larger roles and leadership paths.
Collaborate where it counts : Enjoy the flexibility of remote work with access to in-office opportunities that foster deeper team integration and mentorship.
Be mission-aligned : Work with a team that shares your urgency, attention to detail, and dedication to patients battling cancer and rare diseases.
Why Join Us?
This role offers the opportunity to do more than manage clinical trials — it’s a chance to be at the center of some of the most promising therapeutic advancements in the world. You’ll play a critical role in accelerating the development of treatments that could change patients’ lives forever. If you're looking to grow your career while making a real-world impact, we invite you to apply and join a mission that matters. At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements. Salary Range: The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role. Get to know Syneos Health
Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients. No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health. http://www.syneoshealth.com Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job. Summary We are seeking a skilled and motivated Project Manager I to join our sponsor-dedicated team supporting high-impact oncology and cell & gene therapy trials, including CAR-T studies. In this role, you will work full-time on behalf of a leading biopharmaceutical sponsor while employed within a global CRO—offering the best of both worlds: sponsor collaboration and CRO resources.This position focuses on early-phase trial execution, operational oversight, and cross-functional coordination across global study teams. While remote work is supported, we strongly prefer candidates located near our sponsor’s Los Angeles office to allow for periodic in-office collaboration and faster integration with the sponsor team. At Syneos Health, we are dedicated to building a diverse, inclusive and authentic workplace. If your pastexperience doesn’t align perfectly, we encourage you to apply anyway. At times, we take intoconsideration transferrable skills from previous roles. We also encourage you to join our Talent Network to stay connected to additional career opportunities. Discover what our 29,000 employees already know: work here matters everywhere. We work hard,and smart, all in the name of getting much-needed therapies to thosewho need them most. A career with Syneos Health means your everyday work improvespatients’ lives around the world. Selecting us as an employer secures a career inwhich you’re guaranteed to: Syneos Health (Nasdaq: SYNH) is a leading integrated biopharmaceutical solutionsorganization built to accelerate customer success. We translate unique clinical,medical affairs and commercial insights into outcomes to address modern marketrealities. Together we share insights, use the latest technologies and applyadvanced business practices to speed our customers’ delivery of importanttherapies to patients. We support a diverse, equitable and inclusive culture. Phone: 919 876 9300 Fax: 919 876 9360 Toll-Free: 866 462 7373 Syneos Health is an Equal Opportunity Employer. All qualified applicants will receiveconsideration for employment without regard to race, color, age, religion, marital status,ethnicity, national origin, sex, gender, gender identity, sexual orientation, protectedveteran status, disability or any other legally protected status and will not bediscriminated against. If you are an individual with a disability who requires reasonableaccommodation to complete any part of our application process, including the use of thiswebsite, please contact us at: Email: jobs@syneoshealth.com One of our staff members will workwith you to provide alternate means to submit your application.
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