ZipRecruiter
Research Scientist II/III, DNA Synthesis
ZipRecruiter, Redmond, Washington, United States, 98052
Overview
GenScript Biotech Corporation is a global biotechnology group with operations across North America, Europe, the Greater China region, and Asia Pacific. GenScript’s businesses include life science CRO services, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy. ProBioProBio provides end-to-end CDMO service from drug discovery to commercialization in cell and gene therapy, vaccine, biologics discovery and antibody protein drug development. Job Scope
Location:
Redmond, WA Job Type:
Scientist with multi-disciplinary background in oligonucleotide synthesis, organic/bioorganic synthesis, surface functionalization, and molecular biology. Knowledge of photochemistry and nucleic acid chemistry is a plus. The role involves research and collaboration to improve the company\'s proprietary semiconductor DNA synthesis technology and develop diagnostic applications. Responsibilities
Develop and synthesize desired organic compounds Select and employ analytical techniques for synthesized compounds Develop and perform on-machine oligo synthesis with various modifications Develop surface functionalization for metal and non-metal surfaces for solid-phase oligonucleotide synthesis Select and employ analytical techniques for surface characterization Explore methods to enhance surface stability and functional loading Contribute knowledge in nucleic acid chemistry, specifically phosphoramidite-based oligonucleotide synthesis Technology transfer to the production team and support for process improvement or troubleshooting Perform statistical data analysis and present results Qualifications
Ph.D. in Organic Chemistry, Biochemistry, Chemical Biology, or related field; or M.S. with at least 3 years of relevant industry experience Expertise in nucleoside, nucleotide, and solid-phase oligonucleotide synthesis Strong foundation in organic chemistry and photochemistry In-depth understanding of nucleic acid chemistry and phosphoramidite-based synthesis Hands-on experience with total synthesis and purification techniques (column chromatography, HPLC, Biotage) Ability to handle sensitive materials Familiarity with laboratory automation tools (a plus) Advanced molecular biology skills (PCR, qPCR, hybridization assays, and next-generation sequencing) Proven collaboration within interdisciplinary and cross-functional teams Results-driven with proactive experimental design and problem-solving Excellent written and verbal communication skills Strong documentation skills for technical reports and technology transfer to manufacturing Self-motivated and passionate about biotech innovation Benefits
Medical, Vision, and Dental Insurance 401(k) & Retirement Savings Plan Short-Term Disability New Child Leave Paid Time Off Paid Company Holidays Paid Sick Days Compassionate Leave Jury Duty Leave Float day Personal days Perks
Free meals during shift Onsite massage and fitness facilities Compensation
Salary range: $80,000 – $110,000, depending on experience and qualifications. Equal Opportunity
GenScript USA Inc./ProBio Inc. is an equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company\'s policy to ensure equal employment opportunity without discrimination or harassment based on protected characteristics and other legally protected statuses. GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.
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GenScript Biotech Corporation is a global biotechnology group with operations across North America, Europe, the Greater China region, and Asia Pacific. GenScript’s businesses include life science CRO services, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy. ProBioProBio provides end-to-end CDMO service from drug discovery to commercialization in cell and gene therapy, vaccine, biologics discovery and antibody protein drug development. Job Scope
Location:
Redmond, WA Job Type:
Scientist with multi-disciplinary background in oligonucleotide synthesis, organic/bioorganic synthesis, surface functionalization, and molecular biology. Knowledge of photochemistry and nucleic acid chemistry is a plus. The role involves research and collaboration to improve the company\'s proprietary semiconductor DNA synthesis technology and develop diagnostic applications. Responsibilities
Develop and synthesize desired organic compounds Select and employ analytical techniques for synthesized compounds Develop and perform on-machine oligo synthesis with various modifications Develop surface functionalization for metal and non-metal surfaces for solid-phase oligonucleotide synthesis Select and employ analytical techniques for surface characterization Explore methods to enhance surface stability and functional loading Contribute knowledge in nucleic acid chemistry, specifically phosphoramidite-based oligonucleotide synthesis Technology transfer to the production team and support for process improvement or troubleshooting Perform statistical data analysis and present results Qualifications
Ph.D. in Organic Chemistry, Biochemistry, Chemical Biology, or related field; or M.S. with at least 3 years of relevant industry experience Expertise in nucleoside, nucleotide, and solid-phase oligonucleotide synthesis Strong foundation in organic chemistry and photochemistry In-depth understanding of nucleic acid chemistry and phosphoramidite-based synthesis Hands-on experience with total synthesis and purification techniques (column chromatography, HPLC, Biotage) Ability to handle sensitive materials Familiarity with laboratory automation tools (a plus) Advanced molecular biology skills (PCR, qPCR, hybridization assays, and next-generation sequencing) Proven collaboration within interdisciplinary and cross-functional teams Results-driven with proactive experimental design and problem-solving Excellent written and verbal communication skills Strong documentation skills for technical reports and technology transfer to manufacturing Self-motivated and passionate about biotech innovation Benefits
Medical, Vision, and Dental Insurance 401(k) & Retirement Savings Plan Short-Term Disability New Child Leave Paid Time Off Paid Company Holidays Paid Sick Days Compassionate Leave Jury Duty Leave Float day Personal days Perks
Free meals during shift Onsite massage and fitness facilities Compensation
Salary range: $80,000 – $110,000, depending on experience and qualifications. Equal Opportunity
GenScript USA Inc./ProBio Inc. is an equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company\'s policy to ensure equal employment opportunity without discrimination or harassment based on protected characteristics and other legally protected statuses. GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.
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