ProLynx
Vice President, Translational Pharmacology
ProLynx, Emeryville, California, United States, 94608
Overview
As Vice President, Translational Pharmacology, you will serve as a key member of the executive leadership team, shaping the scientific and clinical strategy that underpins our long-acting therapeutics portfolio. You will provide vision, direction, and external credibility for our pharmacology function, ensuring that data generation, regulatory strategy, and translational science align with the company’s growth objectives and long-term clinical success. This is a strategic leadership position that drives decision-making, influences internal and external stakeholders, and ensures that pharmacology and translational science play a central role in advancing our pipeline. About Us We are a clinical-stage biopharmaceutical company pioneering novel long-acting therapeutics. Our proprietary drug delivery technologies enable controlled, predictable, and sustained release of drugs—peptides, proteins, and small molecules—over weeks or months. This approach enhances pharmacokinetics, efficacy, and safety while dramatically reducing dosing frequency. Our lead programs focus on long- and ultralong-acting anti-obesity peptides, with expansion planned into oncology, immunology, and immuno-oncology. Your Role
Set Strategic Direction: Define and lead the company’s pharmacology and translational science strategy, ensuring alignment with portfolio priorities, regulatory expectations, and long-term business goals. Shape Portfolio Development: Partner with R&D, clinical development, and regulatory leaders to prioritize assets, optimize development plans, and integrate PK/PD learnings into program strategy. Guide External Partnerships: Build and manage strategic relationships with CROs, academic collaborators, and key opinion leaders, ensuring external data generation and partnerships advance company objectives. Support Regulatory Success: Serve as the pharmacology expert in interactions with regulatory agencies, shaping IND/CTA submissions, briefing documents, and scientific strategy to support global approvals. Model & Predict Outcomes: Oversee modeling and simulation approaches to predict human outcomes and inform clinical study design, supporting efficient and successful transitions into the clinic. Executive Leadership: Act as a thought partner to the CEO, CSO, and Board, contributing to company-wide strategy, fundraising, and investor communications by providing pharmacology and translational expertise. Build & Lead Teams: Recruit, mentor, and inspire a high-performing pharmacology organization, fostering a culture of innovation, collaboration, and scientific excellence. Who You Are
Education & Experience: PhD in Pharmacology, Pharmaceutical Sciences, or related discipline, or PharmD with relevant experience in biotechnology. 12+ years of experience in biotech/pharma, with a proven track record of advancing programs from preclinical through early clinical development. Demonstrated leadership in strategic design and interpretation of PK/PD and translational studies, particularly with peptides, biologics, or long-acting modalities. Experience interfacing with FDA and other global regulatory agencies. Strong record of building, leading, and scaling scientific teams. Skills & Qualities: Strategic thinker with the ability to translate complex data into portfolio-level insights and corporate strategy. Influential communicator with Board, investors, and regulators. Adept at balancing scientific rigor with business priorities in a resource-constrained, fast-moving environment. Collaborative leader who thrives in cross-functional, multidisciplinary teams. Employment Details
Seniority level: Not Applicable Employment type: Full-time Job function: Science and Strategy/Planning Industries: Biotechnology
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As Vice President, Translational Pharmacology, you will serve as a key member of the executive leadership team, shaping the scientific and clinical strategy that underpins our long-acting therapeutics portfolio. You will provide vision, direction, and external credibility for our pharmacology function, ensuring that data generation, regulatory strategy, and translational science align with the company’s growth objectives and long-term clinical success. This is a strategic leadership position that drives decision-making, influences internal and external stakeholders, and ensures that pharmacology and translational science play a central role in advancing our pipeline. About Us We are a clinical-stage biopharmaceutical company pioneering novel long-acting therapeutics. Our proprietary drug delivery technologies enable controlled, predictable, and sustained release of drugs—peptides, proteins, and small molecules—over weeks or months. This approach enhances pharmacokinetics, efficacy, and safety while dramatically reducing dosing frequency. Our lead programs focus on long- and ultralong-acting anti-obesity peptides, with expansion planned into oncology, immunology, and immuno-oncology. Your Role
Set Strategic Direction: Define and lead the company’s pharmacology and translational science strategy, ensuring alignment with portfolio priorities, regulatory expectations, and long-term business goals. Shape Portfolio Development: Partner with R&D, clinical development, and regulatory leaders to prioritize assets, optimize development plans, and integrate PK/PD learnings into program strategy. Guide External Partnerships: Build and manage strategic relationships with CROs, academic collaborators, and key opinion leaders, ensuring external data generation and partnerships advance company objectives. Support Regulatory Success: Serve as the pharmacology expert in interactions with regulatory agencies, shaping IND/CTA submissions, briefing documents, and scientific strategy to support global approvals. Model & Predict Outcomes: Oversee modeling and simulation approaches to predict human outcomes and inform clinical study design, supporting efficient and successful transitions into the clinic. Executive Leadership: Act as a thought partner to the CEO, CSO, and Board, contributing to company-wide strategy, fundraising, and investor communications by providing pharmacology and translational expertise. Build & Lead Teams: Recruit, mentor, and inspire a high-performing pharmacology organization, fostering a culture of innovation, collaboration, and scientific excellence. Who You Are
Education & Experience: PhD in Pharmacology, Pharmaceutical Sciences, or related discipline, or PharmD with relevant experience in biotechnology. 12+ years of experience in biotech/pharma, with a proven track record of advancing programs from preclinical through early clinical development. Demonstrated leadership in strategic design and interpretation of PK/PD and translational studies, particularly with peptides, biologics, or long-acting modalities. Experience interfacing with FDA and other global regulatory agencies. Strong record of building, leading, and scaling scientific teams. Skills & Qualities: Strategic thinker with the ability to translate complex data into portfolio-level insights and corporate strategy. Influential communicator with Board, investors, and regulators. Adept at balancing scientific rigor with business priorities in a resource-constrained, fast-moving environment. Collaborative leader who thrives in cross-functional, multidisciplinary teams. Employment Details
Seniority level: Not Applicable Employment type: Full-time Job function: Science and Strategy/Planning Industries: Biotechnology
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