Amylyx Pharmaceutical Corp.
Director, IT Commercial Applications Cambridge, MA - Hybrid
Amylyx Pharmaceutical Corp., Oklahoma City, Oklahoma, United States
Amylyx is a clinical-stage pharmaceutical company based in Cambridge, Massachusetts, focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, progressive supranuclear palsy (PSP), and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people, with core values: be audacious, be curious, be authentic, be engaged, and be accountable. If you share our passion and determination, read the opportunity below and apply.
THE OPPORTUNITY
The Senior IT Leader for Commercial and Medical Affairs will be responsible for driving the strategic direction, implementation, and support of technology solutions that enable Amylyx’s Commercial and Medical functions. This role ensures the delivery of scalable, robust, and compliant applications aligned with evolving business needs. You will lead the IT Commercial Business Partner team, collaborating closely with cross-functional stakeholders—including Supply Chain, Finance, and HR—to ensure technology initiatives enhance operational efficiency and support commercial success. RESPONSIBILITIES
Build strong partnerships across business and technical teams to foster collaboration and effective project execution. Lead the implementation and support of Commercial and Medical business-facing applications, ensuring alignment with strategic priorities. Serve as the primary IT contact for audit and compliance matters related to Commercial and Medical systems, ensuring adherence to regulatory and internal controls. Establish and maintain IT processes and standards for application support within the Commercial and Medical domains. Oversee application enhancements and support activities in alignment with product launch and business objectives. Act as a functional and technical advisor to define, estimate, and propose solutions for business opportunities. Contribute to annual budgeting and planning for Commercial and Medical systems. Administer CRM platforms (e.g., Salesforce, Veeva) for Commercial and Medical Affairs teams. Manage vendor relationships, including assessments and contract negotiations. Coordinate issue resolution with internal teams and external service providers. Maintain the integration roadmap for Commercial and Medical applications (e.g., Commercial Data Environment, HUB, Aggregate Spend, Master Data Management). Lead RFP processes, evaluate proposals, develop ROI analyses, and ensure proper documentation for IT initiatives. Ensure compliance with regulatory requirements, including FDA computer systems assurance, SOX, and GDPR. REQUIRED QUALIFICATIONS
Bachelor’s degree in Computer Science or related field. Minimum 10 years of progressive IT experience, including project and team management. 5+ years of experience with CRM and customer engagement platforms (e.g., Salesforce.com, Veeva). Strong understanding of service delivery and application lifecycle management. Familiarity with data privacy regulations and their application to business operations. Proven ability to lead cross-functional teams and manage external service providers. Experience with enterprise systems and software vendor selection. Excellent communication, analytical, and problem-solving skills. Ability to prioritize tasks and make sound decisions under pressure. Demonstrated success in managing IT projects within controlled change management frameworks. Strong customer service orientation and interpersonal skills. Self-motivated with high attention to detail. PREFERRED REQUIREMENTS
Experience in Life Sciences, particularly within high-growth pharmaceutical or biotech environments. Experience in Commercial, Marketing and/or Medical Operations within Life Sciences. Strong customer service orientation and interpersonal skills. Self-motivated with high attention to detail. Proficiency in managing SaaS-based application implementations. Strong analytical skills with the ability to translate business needs into technical requirements. Experience with commercial applications and data warehousing. Skilled in documenting and analyzing business requirements and functional specifications. Effective facilitator of team collaboration and group sessions. WORK LOCATION AND CONDITIONS
This position is hybrid – we would like someone in the New England area who can come into the office on average 2 times per week – with some flexibility. When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location. Amylyx Pharmaceuticals is an Equal Opportunity Employer and does not discriminate on the basis of protected characteristics. We are committed to providing accommodations in our selection process as needed. If you need an accommodation, please contact Amylyx Talent Acquisition.
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The Senior IT Leader for Commercial and Medical Affairs will be responsible for driving the strategic direction, implementation, and support of technology solutions that enable Amylyx’s Commercial and Medical functions. This role ensures the delivery of scalable, robust, and compliant applications aligned with evolving business needs. You will lead the IT Commercial Business Partner team, collaborating closely with cross-functional stakeholders—including Supply Chain, Finance, and HR—to ensure technology initiatives enhance operational efficiency and support commercial success. RESPONSIBILITIES
Build strong partnerships across business and technical teams to foster collaboration and effective project execution. Lead the implementation and support of Commercial and Medical business-facing applications, ensuring alignment with strategic priorities. Serve as the primary IT contact for audit and compliance matters related to Commercial and Medical systems, ensuring adherence to regulatory and internal controls. Establish and maintain IT processes and standards for application support within the Commercial and Medical domains. Oversee application enhancements and support activities in alignment with product launch and business objectives. Act as a functional and technical advisor to define, estimate, and propose solutions for business opportunities. Contribute to annual budgeting and planning for Commercial and Medical systems. Administer CRM platforms (e.g., Salesforce, Veeva) for Commercial and Medical Affairs teams. Manage vendor relationships, including assessments and contract negotiations. Coordinate issue resolution with internal teams and external service providers. Maintain the integration roadmap for Commercial and Medical applications (e.g., Commercial Data Environment, HUB, Aggregate Spend, Master Data Management). Lead RFP processes, evaluate proposals, develop ROI analyses, and ensure proper documentation for IT initiatives. Ensure compliance with regulatory requirements, including FDA computer systems assurance, SOX, and GDPR. REQUIRED QUALIFICATIONS
Bachelor’s degree in Computer Science or related field. Minimum 10 years of progressive IT experience, including project and team management. 5+ years of experience with CRM and customer engagement platforms (e.g., Salesforce.com, Veeva). Strong understanding of service delivery and application lifecycle management. Familiarity with data privacy regulations and their application to business operations. Proven ability to lead cross-functional teams and manage external service providers. Experience with enterprise systems and software vendor selection. Excellent communication, analytical, and problem-solving skills. Ability to prioritize tasks and make sound decisions under pressure. Demonstrated success in managing IT projects within controlled change management frameworks. Strong customer service orientation and interpersonal skills. Self-motivated with high attention to detail. PREFERRED REQUIREMENTS
Experience in Life Sciences, particularly within high-growth pharmaceutical or biotech environments. Experience in Commercial, Marketing and/or Medical Operations within Life Sciences. Strong customer service orientation and interpersonal skills. Self-motivated with high attention to detail. Proficiency in managing SaaS-based application implementations. Strong analytical skills with the ability to translate business needs into technical requirements. Experience with commercial applications and data warehousing. Skilled in documenting and analyzing business requirements and functional specifications. Effective facilitator of team collaboration and group sessions. WORK LOCATION AND CONDITIONS
This position is hybrid – we would like someone in the New England area who can come into the office on average 2 times per week – with some flexibility. When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location. Amylyx Pharmaceuticals is an Equal Opportunity Employer and does not discriminate on the basis of protected characteristics. We are committed to providing accommodations in our selection process as needed. If you need an accommodation, please contact Amylyx Talent Acquisition.
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