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Amylyx Pharmaceutical Corp.

Senior Manager, Commercial Analytics Cambridge, MA

Amylyx Pharmaceutical Corp., Oklahoma City, Oklahoma, United States

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Overview

Amylyx is a clinical-stage pharmaceutical company based in Cambridge, Massachusetts, with an audacious mission to develop novel therapies for high unmet needs. We are currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, progressive supranuclear palsy (PSP), and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – create a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and determination, we encourage you to read the opportunity below and apply. THE OPPORTUNITY Amylyx Pharmaceuticals is seeking a strategic and hands-on Senior Manager, Commercial Analytics, to join our growing Commercial team. This individual will play a critical role in shaping data-driven decision-making across our lead indication with Avexitide in PBH and future pipeline programs across assets. The ideal candidate will be a highly analytical thinker with deep expertise in healthcare data, capable of independently executing complex analyses and translating insights into actionable strategies. This role offers the opportunity to work cross-functionally with teams including Marketing, Medical Affairs, Market Access, and Supply Chain, and to present findings directly to senior leadership. If you thrive in a fast-paced, mission-driven environment and are passionate about using data to drive impact, we’d love to meet you.

Responsibilities

Lead commercial analytics efforts across PBH and pipeline products, supporting strategic planning and operational execution.

Independently analyze and interpret healthcare datasets (e.g., claims, specialty pharmacy, EMR) using SQL, Excel, and other tools to uncover insights on patient journeys, provider behavior, and market dynamics.

Develop and maintain dashboards and reports that support commercial performance tracking and forecasting.

Translate complex data findings into clear, compelling presentations for cross-functional stakeholders and senior leadership.

Partner with Marketing, Medical Affairs, Market Access, and Supply Chain to align analytics with business needs and strategic priorities.

Support launch readiness and post-launch performance tracking for new products and indications.

Identify opportunities for data acquisition and infrastructure improvements to enhance analytics capabilities.

Collaborate with external vendors and data providers to ensure quality and relevance of third-party data sources.

Stay current on industry trends, competitive intelligence, and emerging data methodologies to continuously elevate the analytics function.

Required Qualifications

5+ years BA/BS, 3+ years MA/MS

Prior experience in consulting (with focus in pharmaceutical industry), or in a commercial operations / analytics function at a pharmaceutical company

Experience working with healthcare data – claims data, EMR/EHR, specialty pharmacy data etc.

Experience with financial modeling / forecasting

Experience in SQL / Other Database Language

Preferred Requirements

Experience working in rare diseases is a plus

Experience supporting multiple brands / indications is a plus

Experience with Python is a plus

Experience in advanced market segmentation approaches (e.g., HCP, patient) is a plus

Work Location and Conditions

At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Delaware, Hawaii and Kansas.

You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.

You must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

Equal Opportunity

Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Visit Amylyx on LinkedIn for updates.

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