Society of Exploration Geophysicists
Associate Scientist/Scientist in Protein Science
Society of Exploration Geophysicists, Palo Alto, California, United States, 94306
Overview
Associate Scientist/Scientist in Protein Science
Location: Bay Area (On-site)
Keywords: Protein Science, Protein Engineering
We are seeking a skilled scientist at the Associate Scientist to Scientist level with a background in Protein Science and Structural Biology in the Bioengineering Department at BioMap. This position will mainly focus on recombinant protein/enzyme production and characterization, computation-aided library generation, high-throughput screening, and structural biology. We are a multi-disciplinary team working closely with computational scientists on mini-binders, nanobodies, antibodies, and enzymes, supporting the discovery of bio-therapeutics through our engineering expertise. The successful candidate has a background in protein science and structural biology, and preferably experience with membrane protein production, protein characterization and HT display methodologies. This is a wonderful opportunity to work with world-class biologists, AI/ML scientists, and engineers to explore the next-generation therapeutical drug development.
Responsibilities
Generate high quality antigens for protein engineering campaigns in various host cells, with focus on the HEK and CHO cell systems.
Work closely with other scientists on protein/enzyme engineering projects by using display technologies, NGS, flow cytometry, liquid handling, microplate reading, etc.
Help design the DNA constructs, and generate the synthetic DNA library by molecular biology techniques, including RT-PCR, gene cloning, mammalian cell transfection, etc.
Analyze libraries by FACS sorting and NGS to screen for lead candidates.
Assist the HT protein/enzyme characterization and in vitro/in vivo assay development.
Collaborate with cross-functional teams for project development.
Routine laboratory instruments maintenance, including mammalian cell cultures, AKTA, HPLC, etc.
Demonstrate ability to combine, analyze, and visualize data from multiple sources.
Attend internal and external meetings to represent the department or company for project presentations.
Qualifications
A Master’s or a Ph.D. degree within subject matter expertise is preferred.
Recombinant protein and enzyme production in mammalian or insect cells, experience with protein purification systems (such as AKTA) and protein characterization (SPR/BLI, functional validation).
Experience with membrane protein generation (preferring nanodiscs format).
Good understanding of antibody and enzyme science.
Experience with different protein formats, such as antibody, nanobody, mini-binder, and enzyme.
Experience with cell-based compound characterization, microscopy, mammalian cell display technologies, flow cytometry, and NGS is a plus.
Experience with therapeutic drug development is a plus.
Familiar with industrial working standards, including LIMS.
Demonstrates excellent verbal and written communication skills.
Good working attitude in a fast-growing organization.
Applications
Please send your CV with subject line: Associate Scientist/Scientist in Protein Science to talent@biomap.com.
#J-18808-Ljbffr
Location: Bay Area (On-site)
Keywords: Protein Science, Protein Engineering
We are seeking a skilled scientist at the Associate Scientist to Scientist level with a background in Protein Science and Structural Biology in the Bioengineering Department at BioMap. This position will mainly focus on recombinant protein/enzyme production and characterization, computation-aided library generation, high-throughput screening, and structural biology. We are a multi-disciplinary team working closely with computational scientists on mini-binders, nanobodies, antibodies, and enzymes, supporting the discovery of bio-therapeutics through our engineering expertise. The successful candidate has a background in protein science and structural biology, and preferably experience with membrane protein production, protein characterization and HT display methodologies. This is a wonderful opportunity to work with world-class biologists, AI/ML scientists, and engineers to explore the next-generation therapeutical drug development.
Responsibilities
Generate high quality antigens for protein engineering campaigns in various host cells, with focus on the HEK and CHO cell systems.
Work closely with other scientists on protein/enzyme engineering projects by using display technologies, NGS, flow cytometry, liquid handling, microplate reading, etc.
Help design the DNA constructs, and generate the synthetic DNA library by molecular biology techniques, including RT-PCR, gene cloning, mammalian cell transfection, etc.
Analyze libraries by FACS sorting and NGS to screen for lead candidates.
Assist the HT protein/enzyme characterization and in vitro/in vivo assay development.
Collaborate with cross-functional teams for project development.
Routine laboratory instruments maintenance, including mammalian cell cultures, AKTA, HPLC, etc.
Demonstrate ability to combine, analyze, and visualize data from multiple sources.
Attend internal and external meetings to represent the department or company for project presentations.
Qualifications
A Master’s or a Ph.D. degree within subject matter expertise is preferred.
Recombinant protein and enzyme production in mammalian or insect cells, experience with protein purification systems (such as AKTA) and protein characterization (SPR/BLI, functional validation).
Experience with membrane protein generation (preferring nanodiscs format).
Good understanding of antibody and enzyme science.
Experience with different protein formats, such as antibody, nanobody, mini-binder, and enzyme.
Experience with cell-based compound characterization, microscopy, mammalian cell display technologies, flow cytometry, and NGS is a plus.
Experience with therapeutic drug development is a plus.
Familiar with industrial working standards, including LIMS.
Demonstrates excellent verbal and written communication skills.
Good working attitude in a fast-growing organization.
Applications
Please send your CV with subject line: Associate Scientist/Scientist in Protein Science to talent@biomap.com.
#J-18808-Ljbffr