Arcinstitute
The Arc Institute is a new scientific institution conducting curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.
While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:
Funding:
Arc fully funds Core Investigators’ (PIs’) research groups, liberating scientists from the typical constraints of project-based external grants. Technology:
Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize, and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators. Support:
Arc aims to provide first-class support—operationally, financially, and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction. Culture:
We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration. Arc has scaled to nearly 200 people. With $650M+ in committed funding and a state-of-the-art new lab facility in Palo Alto, Arc will continue to grow quickly in the coming years. About the position
The Arce Lab investigates the regulatory mechanisms that are required for distinct immune functions in an effort to identify and correct the origins of immune-mediated disease. We are seeking a highly motivated, enthusiastic postdoctoral researcher to join our team at Arc. In this role, you will adapt and integrate cutting edge gene editing techniques and genomic assays to investigate the genetic origins of autoimmune diseases. With consideration for the multi-factorial nature of complex disease, you will design and execute experiments aimed at understanding how dysfunction occurs at a cellular level. From the non-coding genome, to the multimeric proteome, there are opportunities to identify novel mechanisms controlling important immune functions that can be leveraged for therapeutic benefit. Within this role you will have the opportunity to investigate how each of these components contributes to immune homeostasis. You will be expected to make decisions regarding the direction of the project(s) that you lead and work independently on a daily basis. About you
You are deeply curious about the mechanisms that control immune cell function You are a creative problem solver and are resilient in finding solutions You are enthusiastic about the opportunity to develop and refine projects and processes You are passionate about understanding how biological systems work and excited to make discoveries that may improve human health You are self-motivated and work efficiently with diligence You prioritize a positive work environment for yourself and your teammates In this position you will
Investigate the role of autoimmune risk variants on cellular functions Apply CRISPR genome editing in primary human immune cells Generate and analyze single cell multi-omics data Collaborate both internally and with external institutions to pursue the biochemical mechanism of specific regulatory factors Communicate your work in the form of publications and presentations Participate in lab meetings and Institute-wide activities (seminars, symposiums, etc) Requirements
PhD in immunology, genomics, genetics, biological sciences or related fields Highly collaborative team player willing to both learn from and train others Ability to work independently to establish new technical protocols and derive biological insight from findings Resourceful and eager to push forward progress Excellent written and verbal communication skills Preferred Qualifications
Experience with CRISPR gene editing and high throughput screening Proficiency in coding languages such as R or Python for genomic data analysis Experience with immune cell culturing and immunological functional assays The minimum base salary for this position is $80,000. Base salary for this role is determined by how many months of relevant postdoctoral experience a successful candidate has. Base salary for this role is not negotiable. Apply for this job
indicates a required field First Name * Last Name * Email * Phone Country * Phone * Resume/CV * Accepted file types: pdf, doc, docx, txt, rtf LinkedIn Profile Website Are you currently authorized to work in the US? * Will you now, or in the future, require employer visa sponsorship (e.g., H-1B)? * Voluntary Self-Identification
For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Arc Institute’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to VEVRAA, we request this information to measure the effectiveness of our outreach and positive recruitment efforts. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran entitled to compensation under laws administered by the Secretary of Veterans Affairs; or a person discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of discharge or release from active duty. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty during a war or campaign for which a badge has been authorized. An "Armed forces service medal veteran" means a veteran who participated in a U.S. military operation for which an Armed Forces service medal was awarded. Select... Voluntary Self-Identification of Disability
Form CC-305 OMB Control Number 1250-0005 Expires 04/30/2026 PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
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Arc fully funds Core Investigators’ (PIs’) research groups, liberating scientists from the typical constraints of project-based external grants. Technology:
Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize, and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators. Support:
Arc aims to provide first-class support—operationally, financially, and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction. Culture:
We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration. Arc has scaled to nearly 200 people. With $650M+ in committed funding and a state-of-the-art new lab facility in Palo Alto, Arc will continue to grow quickly in the coming years. About the position
The Arce Lab investigates the regulatory mechanisms that are required for distinct immune functions in an effort to identify and correct the origins of immune-mediated disease. We are seeking a highly motivated, enthusiastic postdoctoral researcher to join our team at Arc. In this role, you will adapt and integrate cutting edge gene editing techniques and genomic assays to investigate the genetic origins of autoimmune diseases. With consideration for the multi-factorial nature of complex disease, you will design and execute experiments aimed at understanding how dysfunction occurs at a cellular level. From the non-coding genome, to the multimeric proteome, there are opportunities to identify novel mechanisms controlling important immune functions that can be leveraged for therapeutic benefit. Within this role you will have the opportunity to investigate how each of these components contributes to immune homeostasis. You will be expected to make decisions regarding the direction of the project(s) that you lead and work independently on a daily basis. About you
You are deeply curious about the mechanisms that control immune cell function You are a creative problem solver and are resilient in finding solutions You are enthusiastic about the opportunity to develop and refine projects and processes You are passionate about understanding how biological systems work and excited to make discoveries that may improve human health You are self-motivated and work efficiently with diligence You prioritize a positive work environment for yourself and your teammates In this position you will
Investigate the role of autoimmune risk variants on cellular functions Apply CRISPR genome editing in primary human immune cells Generate and analyze single cell multi-omics data Collaborate both internally and with external institutions to pursue the biochemical mechanism of specific regulatory factors Communicate your work in the form of publications and presentations Participate in lab meetings and Institute-wide activities (seminars, symposiums, etc) Requirements
PhD in immunology, genomics, genetics, biological sciences or related fields Highly collaborative team player willing to both learn from and train others Ability to work independently to establish new technical protocols and derive biological insight from findings Resourceful and eager to push forward progress Excellent written and verbal communication skills Preferred Qualifications
Experience with CRISPR gene editing and high throughput screening Proficiency in coding languages such as R or Python for genomic data analysis Experience with immune cell culturing and immunological functional assays The minimum base salary for this position is $80,000. Base salary for this role is determined by how many months of relevant postdoctoral experience a successful candidate has. Base salary for this role is not negotiable. Apply for this job
indicates a required field First Name * Last Name * Email * Phone Country * Phone * Resume/CV * Accepted file types: pdf, doc, docx, txt, rtf LinkedIn Profile Website Are you currently authorized to work in the US? * Will you now, or in the future, require employer visa sponsorship (e.g., H-1B)? * Voluntary Self-Identification
For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Arc Institute’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to VEVRAA, we request this information to measure the effectiveness of our outreach and positive recruitment efforts. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran entitled to compensation under laws administered by the Secretary of Veterans Affairs; or a person discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of discharge or release from active duty. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty during a war or campaign for which a badge has been authorized. An "Armed forces service medal veteran" means a veteran who participated in a U.S. military operation for which an Armed Forces service medal was awarded. Select... Voluntary Self-Identification of Disability
Form CC-305 OMB Control Number 1250-0005 Expires 04/30/2026 PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
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