Sirtex Medical Limited
Senior Manager, Health Economics and Outcomes Research (HEOR)
Sirtex Medical Limited, Boston, Massachusetts, us, 02298
Senior Manager, Health Economics and Outcomes Research (HEOR)
Sirtex Medical Limited is a global leader in healthcare, with offices in the U.S., Australia, Germany, and Singapore, dedicated to improving patient outcomes. Our mission is to be at the forefront of minimally invasive cancer and embolization therapies, and to partner with physicians to provide innovative products that enhance patient outcomes and simplify treatments. Our flagship product, SIR-Spheres Y-90 resin microspheres, is a targeted radiation therapy for liver cancer. To date, we have delivered over 150K doses across 50+ countries, significantly impacting patients’ lives worldwide. Our success is fueled by a dedication to the medical community, professionalism, collaboration, entrepreneurial spirit, and continuous pursuit of innovation.
At Sirtex, we are committed to creating a great workplace and offer a range of benefits, programs, and services to support our employees, ensuring opportunities to contribute to our success and advance their careers. Join our inclusive community where you can collaborate with talented colleagues, bring your ideas to life, and deliver innovative healthcare solutions to patients.
Base pay range $156,478.00/yr - $195,597.00/yr
The base salary range for this position is within the stated range. Individual compensation will be based on location, skills, experience, and education. This role is eligible to participate in Sirtex’s incentive programs (target bonus of 15% for this position) and benefit plans, including paid time off, health insurance, and 401k matching.
Job Description The Senior Manager, HEOR will lead U.S.-focused health economics and outcomes research strategies and provide strategic support for global HEOR activities across key regions such as the EU and Japan. This role focuses on current portfolio and early/late-stage assets to support market access, pricing, and reimbursement through the generation of high-quality economic evidence and real-world data.
The ideal candidate will have strong expertise in the U.S. payer landscape and evidence expectations (CMS, ICER, commercial payers), combined with experience or familiarity with international HTA processes and reimbursement frameworks (e.g., NICE, HAS, IQWiG, MHLW).
Note: Candidates must be available to work onsite with a hybrid schedule (minimum of 3 days in office and 2 days remote).
Key Responsibilities U.S. Strategy and Execution (Primary Focus):
Lead U.S. HEOR strategy to support access, reimbursement, and pricing decisions across the product lifecycle.
Evaluate early-stage pipeline assets to inform U.S. commercial potential, pricing thresholds, and evidence requirements.
Design and oversee U.S.-specific economic models (cost-effectiveness, budget impact) and real-world evidence (RWE) studies (claims, EMR, registries).
Develop and maintain U.S. AMCP dossiers, ICER submission materials, and payer value communication tools.
Provide insights on U.S. reimbursement pathways (Medicare Part B vs. Part D, buy-and-bill, coding, coverage) and support value-based contracting strategies.
Global Support (EU, Japan, and Other Priority Markets):
Collaborate with global HEOR and affiliate teams to align on evidence generation strategies that meet international HTA requirements (NICE, HAS, IQWiG, MHLW).
Provide input into global health economic models, global value dossiers (GVDs), and clinical trial design to ensure payer-relevant endpoints and data are captured.
Contribute to the development of region-specific adaptations of economic models and RWE studies based on local data and assumptions.
Support pricing and reimbursement submissions in international markets by aligning U.S. insights with global strategies.
Cross-Functional Collaboration:
Partner closely with U.S. Market Access/Reimbursement, Medical Affairs, Clinical Development, Business Development, Regulatory, and Commercial to shape integrated access strategies.
Coordinate with global and regional HEOR counterparts to ensure consistency of value messaging and evidence planning.
Manage external vendors, academic collaborators, and consultants to ensure timely and high-quality execution of projects.
Communication and Dissemination:
Present HEOR data at internal forums, scientific congresses (e.g., ISPOR, AMCP), and contribute to peer-reviewed publications.
Translate technical findings into impactful insights and recommendations for internal stakeholders and external decision-makers.
Qualifications Education: Advanced degree (PhD, PharmD, MPH, MS, or equivalent) in Health Economics, Public Health, Epidemiology, Pharmacy, or a related field.
Minimum 5–8 years of HEOR experience in the pharmaceutical, biotechnology, or healthcare consulting industry.
Strong background in U.S. payer evidence requirements, pricing and reimbursement processes, and health policy landscape.
Familiarity with international HTA systems and value assessment methodologies (e.g., NICE, ICER, IQWiG, MHLW).
Hands-on experience developing economic models and managing RWE studies.
Experience supporting both pre-launch and post-launch assets.
Therapeutic area experience in oncology, rare disease, or specialty therapeutics.
Skills
Strategic mindset with the ability to balance U.S. and global evidence needs.
Excellent project management skills and vendor oversight.
Strong scientific writing and communication skills, including the ability to translate complex analyses into clear insights.
Collaborative and team-oriented, with experience working in a global matrix environment.
Entrepreneurial, resourceful, tenacious and diplomatic.
Flexible and adaptable style with the ability to learn and assimilate information quickly.
Committed to delivering high quality results on time.
Resilient and able to remain solution-focused in challenging situations.
EEO and Benefits All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age, or any other characteristic protected under applicable law. Sirtex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Additional Information Sirtex offers diverse and flexible work arrangements, a culture of respect and collaboration, attractive compensation and benefit packages, opportunities for professional growth, challenging work to improve oncology outcomes, and a commitment to company values, safety, and excellence.
#J-18808-Ljbffr
At Sirtex, we are committed to creating a great workplace and offer a range of benefits, programs, and services to support our employees, ensuring opportunities to contribute to our success and advance their careers. Join our inclusive community where you can collaborate with talented colleagues, bring your ideas to life, and deliver innovative healthcare solutions to patients.
Base pay range $156,478.00/yr - $195,597.00/yr
The base salary range for this position is within the stated range. Individual compensation will be based on location, skills, experience, and education. This role is eligible to participate in Sirtex’s incentive programs (target bonus of 15% for this position) and benefit plans, including paid time off, health insurance, and 401k matching.
Job Description The Senior Manager, HEOR will lead U.S.-focused health economics and outcomes research strategies and provide strategic support for global HEOR activities across key regions such as the EU and Japan. This role focuses on current portfolio and early/late-stage assets to support market access, pricing, and reimbursement through the generation of high-quality economic evidence and real-world data.
The ideal candidate will have strong expertise in the U.S. payer landscape and evidence expectations (CMS, ICER, commercial payers), combined with experience or familiarity with international HTA processes and reimbursement frameworks (e.g., NICE, HAS, IQWiG, MHLW).
Note: Candidates must be available to work onsite with a hybrid schedule (minimum of 3 days in office and 2 days remote).
Key Responsibilities U.S. Strategy and Execution (Primary Focus):
Lead U.S. HEOR strategy to support access, reimbursement, and pricing decisions across the product lifecycle.
Evaluate early-stage pipeline assets to inform U.S. commercial potential, pricing thresholds, and evidence requirements.
Design and oversee U.S.-specific economic models (cost-effectiveness, budget impact) and real-world evidence (RWE) studies (claims, EMR, registries).
Develop and maintain U.S. AMCP dossiers, ICER submission materials, and payer value communication tools.
Provide insights on U.S. reimbursement pathways (Medicare Part B vs. Part D, buy-and-bill, coding, coverage) and support value-based contracting strategies.
Global Support (EU, Japan, and Other Priority Markets):
Collaborate with global HEOR and affiliate teams to align on evidence generation strategies that meet international HTA requirements (NICE, HAS, IQWiG, MHLW).
Provide input into global health economic models, global value dossiers (GVDs), and clinical trial design to ensure payer-relevant endpoints and data are captured.
Contribute to the development of region-specific adaptations of economic models and RWE studies based on local data and assumptions.
Support pricing and reimbursement submissions in international markets by aligning U.S. insights with global strategies.
Cross-Functional Collaboration:
Partner closely with U.S. Market Access/Reimbursement, Medical Affairs, Clinical Development, Business Development, Regulatory, and Commercial to shape integrated access strategies.
Coordinate with global and regional HEOR counterparts to ensure consistency of value messaging and evidence planning.
Manage external vendors, academic collaborators, and consultants to ensure timely and high-quality execution of projects.
Communication and Dissemination:
Present HEOR data at internal forums, scientific congresses (e.g., ISPOR, AMCP), and contribute to peer-reviewed publications.
Translate technical findings into impactful insights and recommendations for internal stakeholders and external decision-makers.
Qualifications Education: Advanced degree (PhD, PharmD, MPH, MS, or equivalent) in Health Economics, Public Health, Epidemiology, Pharmacy, or a related field.
Minimum 5–8 years of HEOR experience in the pharmaceutical, biotechnology, or healthcare consulting industry.
Strong background in U.S. payer evidence requirements, pricing and reimbursement processes, and health policy landscape.
Familiarity with international HTA systems and value assessment methodologies (e.g., NICE, ICER, IQWiG, MHLW).
Hands-on experience developing economic models and managing RWE studies.
Experience supporting both pre-launch and post-launch assets.
Therapeutic area experience in oncology, rare disease, or specialty therapeutics.
Skills
Strategic mindset with the ability to balance U.S. and global evidence needs.
Excellent project management skills and vendor oversight.
Strong scientific writing and communication skills, including the ability to translate complex analyses into clear insights.
Collaborative and team-oriented, with experience working in a global matrix environment.
Entrepreneurial, resourceful, tenacious and diplomatic.
Flexible and adaptable style with the ability to learn and assimilate information quickly.
Committed to delivering high quality results on time.
Resilient and able to remain solution-focused in challenging situations.
EEO and Benefits All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age, or any other characteristic protected under applicable law. Sirtex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Additional Information Sirtex offers diverse and flexible work arrangements, a culture of respect and collaboration, attractive compensation and benefit packages, opportunities for professional growth, challenging work to improve oncology outcomes, and a commitment to company values, safety, and excellence.
#J-18808-Ljbffr