Revolution Medicines
Executive Director, Clinical Development
Revolution Medicines, San Francisco, California, United States, 94199
Executive Director, Clinical Development
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Executive Director, Clinical Development
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Revolution Medicines . Overview
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity
We are seeking an experienced drug developer and effective leader to serve as Executive Director of Clinical Development in support of Revolution Medicines’ clinical-stage molecule(s) and/or pre-clinical molecule(s). In this critical role, you will be responsible for developing the strategic plans and ensuring efficient operational execution of the molecule(s)’ clinical development program in one or more disease indications, from early-stage studies to regulatory submissions and potential commercialization. You will play a pivotal role in shaping the future of our pipeline and driving the development of transformative therapies for patients. Responsibilities
Provide critical insights/contributions and implement comprehensive/execute upon the clinical development plans for Revolution Medicines’ molecules, ensuring alignment with scientific, regulatory, and commercial objectives. Lead, mentor, and manage a high-performing cross-functional team of clinical development professionals, fostering a culture of collaboration, innovation, and excellence. Oversee all aspects of clinical trial design and execution, including site selection, patient recruitment, data management, and regulatory compliance. Establish and maintain strong relationships with clinical investigators, regulatory agencies, and key stakeholders. Gather, analyze and interpret clinical data, providing strategic insights to inform critical decisions and guide program development. Manage clinical development timelines effectively, ensuring efficient resource allocation and achievement of milestones. Stay abreast of the latest scientific advancements and regulatory trends in the field of clinical development. Partner with cross-functional teams, including research, regulatory affairs, commercial, and finance, to ensure seamless program execution and achieve shared goals. Manage multiple direct reports; potentially be a manager of managers. Required Skills, Experience and Education
MD with 13+ years of experience in the pharmaceutical/biotech industry or an academic background at the level of Associate Professor or higher. Extensive experience with data analysis, interpretation, and clinical relevance as it relates to the pharmaceutical/biotech industry. Proven track record of designing and conducting multiple clinical trials as part of broader clinical development programs, including Phase 1 drug development. Experience authoring clinical development strategies and bringing them forward for governance. Extensive understanding of medical aspects of GCP, ICH, FDA, EMA, and other relevant guidelines and regulations. Proven experience guiding an Investigational Medicinal Product (IMP) through its clinical development plan with major Health Authority interactions (e.g., FDA, EMA, others). Has led Health Authority interactions. Strong orientation to teamwork and excellent leadership, communication, and interpersonal skills, with the ability to inspire and mentor a diverse team. Expertise in building and maintaining relationships with internal and external stakeholders. Strategic thinking and analytical skills to make data-driven decisions in a fast-paced environment, with the ability to prioritize and set goals. Outstanding written and business presentation skills; experience publishing results of a clinical trial in a peer-reviewed journal is required. Proven ability to manage budgets and timelines effectively. Passion for innovation and a commitment to developing therapies that make a meaningful difference in patients' lives. Preferred Skills
Experience enhancing core and sub-team processes, structures, systems, tools, and resources in the pharmaceutical/biotech industry. Experience creating clinical development strategies that led to label-enabling outcomes and commercialization. Experience submitting an NDA/BLA/MAA to global health authorities is a significant plus. Led regulatory and internal partner interactions in regulatory documentation; provided clinical science input for regulatory development of labels and packaging language. Oversaw data generation to address unmet medical needs and identify new or extended Clinical Development studies for the assigned program or other programs. Direct experience with Phase IV drug development. Ability to present a compelling business case and facilitate effective, expedited decision-making; capable of serving as a company spokesperson internally and externally. Collaborative behaviors on enterprise-level strategic initiatives with clinical investigators, scientists, KOLs, and internal groups, leading to tangible outcomes. Demonstrated courage and conviction, with skills in conflict resolution. Compensation and Other Details
The base salary range for this full-time position is $357,000 to $410,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on postings is intended for onsite roles and will be adjusted for the local market. Individual pay is determined by role, level, location, and other factors. Base salary is one part of the total rewards program, which includes competitive cash compensation, equity awards, benefits, and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes the protection and security of personal data seriously and respects your privacy. We collect, process and use personal data in accordance with our CCPA Notice and Privacy Policy. For more information, please contact privacy@revmed.com. Organization and Roles
Seniority level: Director Employment type: Full-time Job function: Research, Analyst, and Information Technology
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Join to apply for the
Executive Director, Clinical Development
role at
Revolution Medicines . Overview
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity
We are seeking an experienced drug developer and effective leader to serve as Executive Director of Clinical Development in support of Revolution Medicines’ clinical-stage molecule(s) and/or pre-clinical molecule(s). In this critical role, you will be responsible for developing the strategic plans and ensuring efficient operational execution of the molecule(s)’ clinical development program in one or more disease indications, from early-stage studies to regulatory submissions and potential commercialization. You will play a pivotal role in shaping the future of our pipeline and driving the development of transformative therapies for patients. Responsibilities
Provide critical insights/contributions and implement comprehensive/execute upon the clinical development plans for Revolution Medicines’ molecules, ensuring alignment with scientific, regulatory, and commercial objectives. Lead, mentor, and manage a high-performing cross-functional team of clinical development professionals, fostering a culture of collaboration, innovation, and excellence. Oversee all aspects of clinical trial design and execution, including site selection, patient recruitment, data management, and regulatory compliance. Establish and maintain strong relationships with clinical investigators, regulatory agencies, and key stakeholders. Gather, analyze and interpret clinical data, providing strategic insights to inform critical decisions and guide program development. Manage clinical development timelines effectively, ensuring efficient resource allocation and achievement of milestones. Stay abreast of the latest scientific advancements and regulatory trends in the field of clinical development. Partner with cross-functional teams, including research, regulatory affairs, commercial, and finance, to ensure seamless program execution and achieve shared goals. Manage multiple direct reports; potentially be a manager of managers. Required Skills, Experience and Education
MD with 13+ years of experience in the pharmaceutical/biotech industry or an academic background at the level of Associate Professor or higher. Extensive experience with data analysis, interpretation, and clinical relevance as it relates to the pharmaceutical/biotech industry. Proven track record of designing and conducting multiple clinical trials as part of broader clinical development programs, including Phase 1 drug development. Experience authoring clinical development strategies and bringing them forward for governance. Extensive understanding of medical aspects of GCP, ICH, FDA, EMA, and other relevant guidelines and regulations. Proven experience guiding an Investigational Medicinal Product (IMP) through its clinical development plan with major Health Authority interactions (e.g., FDA, EMA, others). Has led Health Authority interactions. Strong orientation to teamwork and excellent leadership, communication, and interpersonal skills, with the ability to inspire and mentor a diverse team. Expertise in building and maintaining relationships with internal and external stakeholders. Strategic thinking and analytical skills to make data-driven decisions in a fast-paced environment, with the ability to prioritize and set goals. Outstanding written and business presentation skills; experience publishing results of a clinical trial in a peer-reviewed journal is required. Proven ability to manage budgets and timelines effectively. Passion for innovation and a commitment to developing therapies that make a meaningful difference in patients' lives. Preferred Skills
Experience enhancing core and sub-team processes, structures, systems, tools, and resources in the pharmaceutical/biotech industry. Experience creating clinical development strategies that led to label-enabling outcomes and commercialization. Experience submitting an NDA/BLA/MAA to global health authorities is a significant plus. Led regulatory and internal partner interactions in regulatory documentation; provided clinical science input for regulatory development of labels and packaging language. Oversaw data generation to address unmet medical needs and identify new or extended Clinical Development studies for the assigned program or other programs. Direct experience with Phase IV drug development. Ability to present a compelling business case and facilitate effective, expedited decision-making; capable of serving as a company spokesperson internally and externally. Collaborative behaviors on enterprise-level strategic initiatives with clinical investigators, scientists, KOLs, and internal groups, leading to tangible outcomes. Demonstrated courage and conviction, with skills in conflict resolution. Compensation and Other Details
The base salary range for this full-time position is $357,000 to $410,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on postings is intended for onsite roles and will be adjusted for the local market. Individual pay is determined by role, level, location, and other factors. Base salary is one part of the total rewards program, which includes competitive cash compensation, equity awards, benefits, and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes the protection and security of personal data seriously and respects your privacy. We collect, process and use personal data in accordance with our CCPA Notice and Privacy Policy. For more information, please contact privacy@revmed.com. Organization and Roles
Seniority level: Director Employment type: Full-time Job function: Research, Analyst, and Information Technology
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