Lumicity
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$220,000.00/yr - $260,000.00/yr Direct message the job poster from Lumicity Recruitment Consultant | Biotech, Biopharma and Pharmaceutical | United States
Salary: $220,000-$260,000 annually Job Title:
Senior Medical Director – Cardiovascular Medicine & Clinical Development Location:
Massachusetts (On-Site) Job Description: An emerging biotechnology company is seeking a
Senior Medical Director
to lead the clinical development strategy and execution for a first-in-class therapeutic candidate targeting
Hypertrophic Cardiomyopathy (HCM) . This pivotal leadership role offers the opportunity to shape and drive innovative approaches in cardiovascular medicine within a dynamic, science-driven environment. You will play a central role in the company’s mission to develop transformative
RNA-based therapies . Responsibilities include overseeing early-phase clinical trials, integrating precision medicine into trial designs, and ensuring rigorous medical and regulatory oversight. You will collaborate across preclinical, clinical, regulatory, and commercial functions to ensure clinical strategy is aligned with company goals. Key Responsibilities: Therapeutic Area Leadership: Lead clinical strategy and execution for a pipeline asset in
HCM
and related cardiomyopathies. Guide the development of precision therapeutics by incorporating insights from translational science and biomarker research. Collaborate with internal and external experts to advance the program from early development to pivotal trials. Ensure the program reflects the latest advances in cardiovascular biology and therapeutic innovation. Clinical Development & Medical Oversight: Design and oversee early-phase clinical trials, including first-in-human studies. Serve as medical lead and monitor across key studies. Collaborate with biomarker, imaging, and genomics teams to optimize patient selection and trial endpoints. Ensure regulatory and ethical standards are met for global submissions. Cross-Functional Collaboration: Work closely with cross-functional teams including research, clinical operations, regulatory, and executive leadership. Engage with external stakeholders including KOLs, advisory boards, and safety monitoring boards. Stay abreast of emerging scientific literature in HCM and RNA-based or genetic medicine. Regulatory & Strategic Support: Contribute to the preparation and review of regulatory submissions and clinical trial applications (IND/CTA). Ensure alignment with global regulatory standards and agencies (FDA, EMA, etc.). Qualifications: MD or MD/PhD with a focus in cardiology or a related discipline. 10+ years in cardiovascular clinical development, including significant experience in HCM or genetic cardiomyopathies. Experience leading clinical programs through early development stages. Board Certification in Cardiology or a related field is highly desirable. Experience in RNA therapeutics, genetic medicine, or rare diseases is a plus but not required. If interested, please apply below or send CV to ethan.herman@lumicity.io Seniority level
Seniority level Director Employment type
Employment type Full-time Job function
Job function Science Industries Pharmaceutical Manufacturing Referrals increase your chances of interviewing at Lumicity by 2x Sign in to set job alerts for “Medical Director” roles.
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We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
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$220,000.00/yr - $260,000.00/yr Direct message the job poster from Lumicity Recruitment Consultant | Biotech, Biopharma and Pharmaceutical | United States
Salary: $220,000-$260,000 annually Job Title:
Senior Medical Director – Cardiovascular Medicine & Clinical Development Location:
Massachusetts (On-Site) Job Description: An emerging biotechnology company is seeking a
Senior Medical Director
to lead the clinical development strategy and execution for a first-in-class therapeutic candidate targeting
Hypertrophic Cardiomyopathy (HCM) . This pivotal leadership role offers the opportunity to shape and drive innovative approaches in cardiovascular medicine within a dynamic, science-driven environment. You will play a central role in the company’s mission to develop transformative
RNA-based therapies . Responsibilities include overseeing early-phase clinical trials, integrating precision medicine into trial designs, and ensuring rigorous medical and regulatory oversight. You will collaborate across preclinical, clinical, regulatory, and commercial functions to ensure clinical strategy is aligned with company goals. Key Responsibilities: Therapeutic Area Leadership: Lead clinical strategy and execution for a pipeline asset in
HCM
and related cardiomyopathies. Guide the development of precision therapeutics by incorporating insights from translational science and biomarker research. Collaborate with internal and external experts to advance the program from early development to pivotal trials. Ensure the program reflects the latest advances in cardiovascular biology and therapeutic innovation. Clinical Development & Medical Oversight: Design and oversee early-phase clinical trials, including first-in-human studies. Serve as medical lead and monitor across key studies. Collaborate with biomarker, imaging, and genomics teams to optimize patient selection and trial endpoints. Ensure regulatory and ethical standards are met for global submissions. Cross-Functional Collaboration: Work closely with cross-functional teams including research, clinical operations, regulatory, and executive leadership. Engage with external stakeholders including KOLs, advisory boards, and safety monitoring boards. Stay abreast of emerging scientific literature in HCM and RNA-based or genetic medicine. Regulatory & Strategic Support: Contribute to the preparation and review of regulatory submissions and clinical trial applications (IND/CTA). Ensure alignment with global regulatory standards and agencies (FDA, EMA, etc.). Qualifications: MD or MD/PhD with a focus in cardiology or a related discipline. 10+ years in cardiovascular clinical development, including significant experience in HCM or genetic cardiomyopathies. Experience leading clinical programs through early development stages. Board Certification in Cardiology or a related field is highly desirable. Experience in RNA therapeutics, genetic medicine, or rare diseases is a plus but not required. If interested, please apply below or send CV to ethan.herman@lumicity.io Seniority level
Seniority level Director Employment type
Employment type Full-time Job function
Job function Science Industries Pharmaceutical Manufacturing Referrals increase your chances of interviewing at Lumicity by 2x Sign in to set job alerts for “Medical Director” roles.
Head (Executive Director) Rare Disease, US Medical Affairs
Vice President International Patient Center
Massachusetts, United States $150.00-$210.00 2 weeks ago Executive Director, Medical Affairs – APAC Regional Head
Boston, MA $160,000.00-$180,000.00 2 weeks ago Associate Medical Director, Epilepsy and Neurodevelopment
Site Director – (PACE Center) – Great Opportunity Lowell, MA
Medical Director, Global Medical Safety (Remote)
Boston, MA $228,200.00-$358,600.00 3 days ago Director, Global Reg CMC for Combination Products and Medical Devices
Vice President, Pathology and Clinical Development Services
VP, Associate Chief Nursing Officer - Medical, Surgical, Procedural
Boston, MA $190,000.00-$250,000.00 3 weeks ago Director, Medical Affairs – Advanced Wound Care (AWC)
Medical Director/Senior Medical Director, Medical Affairs (Remote)
Regional Director of Operations and Development
Medical Director/ Senior Medical Director
Cambridge, MA $304,000.00-$380,000.00 1 week ago Director, Scientific and Medical Education
Lenox, MA $117,000.00-$125,000.00 1 week ago Associate Medical Director of Clinical Development
We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr