Bristol Myers Squibb
Scientist Protein Engineering Display Technologies
Bristol Myers Squibb, Redwood City, California, United States, 94061
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Scientist Protein Engineering Display Technologies
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Bristol Myers Squibb Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Position Summary
We are seeking an enthusiastic, creative, and versatile Scientist to join our collaborative Protein Engineering team in Redwood City/Brisbane (CA) to discover and engineer innovative biotherapeutic candidates and drive technological innovation. Responsibilities
Drive efforts to engineer antibodies, multispecifics, and alternative biologics formats for optimal therapeutic performance Selections on yeast display libraries, routine operation and maintenance of a sorter and analyzer Library design, library construction, NGS Collaborate with AI/ML scientists for sequence and library design and support design-build-test cycles. Independently perform routine molecular biology techniques, DNA assembly and cloning, design expression constructs for external synthesis, and coordinate construct and library orders with CROs Analyze library NGS data using no-code or low-code bioinformatics platforms Independently perform complex experiments, troubleshoot, expertly analyze and interpret experimental results with strong attention to detail and documentation practices Present results internally and externally, attend industry conferences Accomplish goals under project team timelines Basic Qualifications
Bachelor's Degree with 5+ years of academic or industry experience Master's Degree with 3+ years of academic or industry experience PhD in Biochemistry, Bioengineering, Molecular Biology, or related fields with 0-2 years of academic or industry experience Preferred Qualifications
PhD in Biochemistry, Bioengineering, Molecular Biology, or related fields with 0-2 years of relevant post-graduate or biotech/biopharma industry experience Experience with molecular and microbiology techniques underlying yeast display work Demonstrated experience in yeast display, antibody/protein library construction, sorting, analytical binding, etc. Experience in antibody or protein engineering, including, but not limited to, affinity maturation, deep mutational scanning, species cross-reactivity, liability correction, biophysical/physiochemical property remediation, etc. Flow cytometry and FACS experience is required Experience in biotherapeutic lead discovery and optimization is desirable Demonstrated experience in working in a cross-functional organization Fundamental understanding of proteins, antibodies, and structure-function relationships required. DNA and RNA purification, cloning, PCR, Sanger sequencing, NGS library preparation Familiarity with protein-protein interaction techniques and kinetics (BLI, SPR, on-cell binding) Bioinformatics or data science experience is desirable (bash, Python, or R) Proficiency with Microsoft Office suite, FlowJo, Prism, DNA cloning software Excellent written and oral communication skills The starting compensation for this job is a range from $122,830 - $148,800, plus incentive cash and stock opportunities (based on eligibility). BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities.
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Scientist Protein Engineering Display Technologies
role at
Bristol Myers Squibb Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Position Summary
We are seeking an enthusiastic, creative, and versatile Scientist to join our collaborative Protein Engineering team in Redwood City/Brisbane (CA) to discover and engineer innovative biotherapeutic candidates and drive technological innovation. Responsibilities
Drive efforts to engineer antibodies, multispecifics, and alternative biologics formats for optimal therapeutic performance Selections on yeast display libraries, routine operation and maintenance of a sorter and analyzer Library design, library construction, NGS Collaborate with AI/ML scientists for sequence and library design and support design-build-test cycles. Independently perform routine molecular biology techniques, DNA assembly and cloning, design expression constructs for external synthesis, and coordinate construct and library orders with CROs Analyze library NGS data using no-code or low-code bioinformatics platforms Independently perform complex experiments, troubleshoot, expertly analyze and interpret experimental results with strong attention to detail and documentation practices Present results internally and externally, attend industry conferences Accomplish goals under project team timelines Basic Qualifications
Bachelor's Degree with 5+ years of academic or industry experience Master's Degree with 3+ years of academic or industry experience PhD in Biochemistry, Bioengineering, Molecular Biology, or related fields with 0-2 years of academic or industry experience Preferred Qualifications
PhD in Biochemistry, Bioengineering, Molecular Biology, or related fields with 0-2 years of relevant post-graduate or biotech/biopharma industry experience Experience with molecular and microbiology techniques underlying yeast display work Demonstrated experience in yeast display, antibody/protein library construction, sorting, analytical binding, etc. Experience in antibody or protein engineering, including, but not limited to, affinity maturation, deep mutational scanning, species cross-reactivity, liability correction, biophysical/physiochemical property remediation, etc. Flow cytometry and FACS experience is required Experience in biotherapeutic lead discovery and optimization is desirable Demonstrated experience in working in a cross-functional organization Fundamental understanding of proteins, antibodies, and structure-function relationships required. DNA and RNA purification, cloning, PCR, Sanger sequencing, NGS library preparation Familiarity with protein-protein interaction techniques and kinetics (BLI, SPR, on-cell binding) Bioinformatics or data science experience is desirable (bash, Python, or R) Proficiency with Microsoft Office suite, FlowJo, Prism, DNA cloning software Excellent written and oral communication skills The starting compensation for this job is a range from $122,830 - $148,800, plus incentive cash and stock opportunities (based on eligibility). BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities.
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