Generate:Biomedicines
Senior Scientist I, Protein Engineering and Synthetic Biology
Generate:Biomedicines, Somerville, Massachusetts, us, 02145
Overview
Senior Scientist I, Protein Engineering and Synthetic Biology at Generate:Biomedicines. The Protein Engineering team seeks a highly innovative and collaborative Senior Scientist I to drive the development and implementation of large-scale, NGS-based functional assays. In this role, you will lead the translation of Generate’s cutting-edge technologies into high-impact therapeutic applications that harness the full power of our computational and experimental platforms. This role collaborates with teams across DNA Read/Write, Prototyping Lab, Machine Learning, and Early-Stage Biology to pioneer novel workflows for scalable functional screening. Responsibilities
Design and implement state-of-the art large-scale quantitative assays to evaluate the biological function of protein designs Collaborate with computational teams to guide experimental design and data analysis Translate emerging technologies from Prototyping Lab into scalable, validated platforms for therapeutic exploration Communicate experimental strategies, results, and insights clearly and effectively across multidisciplinary teams Support platform innovation with theoretical analysis, modeling, and literature review Generate novel intellectual property and contribute to patent filings Qualifications
PhD in biomedical engineering, synthetic or systems biology, biophysics, or related discipline with 4+ years of relevant experience or BS/MS with 10+ years of relevant experience. Exceptional candidates with fewer years of experience may also be considered Expertise in synthetic biology or protein engineering, with particular emphasis on DNA library construction, protein library screening, and NGS assay development Proficiency in computational analysis using Python, MATLAB, or related tools, particularly for NGS and high-throughput datasets Experience with gene editing technologies for developing engineered cell lines Strong quantitative mindset and scientific intuition Demonstrated ability to translate experimental tools into biologically meaningful applications Highly collaborative, intellectually curious, and motivated to work across disciplines Experience with computational modeling and/or laboratory automation is a plus Compensation & Benefits
Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Compensation : The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package. Per Year Salary Range $124,000 — $174,000 USD Employment details
Seniority level: Mid-Senior level Employment type: Full-time Job function: Research
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Senior Scientist I, Protein Engineering and Synthetic Biology at Generate:Biomedicines. The Protein Engineering team seeks a highly innovative and collaborative Senior Scientist I to drive the development and implementation of large-scale, NGS-based functional assays. In this role, you will lead the translation of Generate’s cutting-edge technologies into high-impact therapeutic applications that harness the full power of our computational and experimental platforms. This role collaborates with teams across DNA Read/Write, Prototyping Lab, Machine Learning, and Early-Stage Biology to pioneer novel workflows for scalable functional screening. Responsibilities
Design and implement state-of-the art large-scale quantitative assays to evaluate the biological function of protein designs Collaborate with computational teams to guide experimental design and data analysis Translate emerging technologies from Prototyping Lab into scalable, validated platforms for therapeutic exploration Communicate experimental strategies, results, and insights clearly and effectively across multidisciplinary teams Support platform innovation with theoretical analysis, modeling, and literature review Generate novel intellectual property and contribute to patent filings Qualifications
PhD in biomedical engineering, synthetic or systems biology, biophysics, or related discipline with 4+ years of relevant experience or BS/MS with 10+ years of relevant experience. Exceptional candidates with fewer years of experience may also be considered Expertise in synthetic biology or protein engineering, with particular emphasis on DNA library construction, protein library screening, and NGS assay development Proficiency in computational analysis using Python, MATLAB, or related tools, particularly for NGS and high-throughput datasets Experience with gene editing technologies for developing engineered cell lines Strong quantitative mindset and scientific intuition Demonstrated ability to translate experimental tools into biologically meaningful applications Highly collaborative, intellectually curious, and motivated to work across disciplines Experience with computational modeling and/or laboratory automation is a plus Compensation & Benefits
Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Compensation : The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package. Per Year Salary Range $124,000 — $174,000 USD Employment details
Seniority level: Mid-Senior level Employment type: Full-time Job function: Research
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