Mantell Associates
Senior Director Program Management
Mantell Associates, Oklahoma City, Oklahoma, United States
Get AI-powered advice on this job and more exclusive features.
Direct message the job poster from Mantell Associates
Associate at Mantell Associates | CGT Specialist Headhunter
Mantell Associates is partnered with an innovative Cell & Gene Therapy organisation, who is seeking an experienced Senior Director of Program Management to lead cross-functional program teams in the development of advanced cell and/or gene therapy programs. The successful candidate will be responsible for driving strategic planning, execution, and delivery of complex projects across research, CMC, clinical, regulatory, and commercial functions. This is a high-impact role requiring leadership, strategic insight, and deep understanding of the biotech product development lifecycle. Senior Director of Program Management - Responsibilities: Lead cross-functional program teams including R&D, CMC, regulatory, clinical, commercial, and business development Develop and maintain comprehensive program plans, timelines, budgets, and risk management strategies Act as the primary point of contact for program-level communication and updates to executive leadership and stakeholders Ensure alignment with corporate strategy, milestones, and financial targets Coordinate with CMC, clinical operations, and regulatory affairs to drive IND/CTA submissions, clinical trials, and BLA/MAA readiness Manage external partnerships including CROs, CDMOs, academic collaborators, and licensing partners Drive decision-making through well-prepared governance presentations and scenario planning Anticipate and mitigate program risks and interdependencies Maintain program documentation and ensure compliance with internal governance and regulatory expectations Senior Director of Program Management - Requirements: Advanced degree in life sciences (PhD, PharmD, MD, or MS); MBA is a plus 10+ years of experience in biotech/pharmaceutical industry, including 5+ years of program management experience Deep expertise in cell and/or gene therapy, including understanding of vector manufacturing, regulatory landscape, and clinical development nuances Experience with rare diseases, oncology, or immunotherapy indications preferred Previous success in global development programs, including FDA and EMA interactions preferred PMP certification or formal project management training preferred Proven track record in leading cross-functional drug development teams from preclinical through clinical and ideally into commercialization Strong leadership, interpersonal, and influencing skills across matrixed organizations Excellent communication, presentation, and organizational skills Experience with tools like MS Project, Smartsheet, or other project planning software Mantell Associates is a specialist Pharmaceutical and Life Science headhunting firm. For more information on this opportunity, contact us at +44 (0)20 3854 7700. Seniority level
Seniority level Director Employment type
Employment type Full-time Job function
Job function Management, Project Management, and Research Industries Biotechnology Research, Pharmaceutical Manufacturing, and Medical Equipment Manufacturing Referrals increase your chances of interviewing at Mantell Associates by 2x Sign in to set job alerts for “Director Program Management” roles.
Associate Director/Director, Project Management
Vice President Director, Project Management
Boston, MA $119,510 - $179,850 2 weeks ago Senior Director, Enterprise Projects and Initiatives Center
Boston, MA $151,500.00 - $222,200.00 1 day ago Director, Project Management & R&D Operations
Director, Early Global Program Team Leader
Cambridge, MA $130,000.00 - $150,000.00 1 week ago Boston, MA $90,000.00 - $100,000.00 6 days ago Haverhill, MA $95,000.00 - $106,000.00 2 weeks ago Boston, MA $175,000.00 - $185,000.00 2 weeks ago Boston, MA $175,000.00 - $190,000.00 3 weeks ago Director of Operations - Medical Device Manufacturing
Site Director – (PACE Center) – Great Opportunity Lowell, MA
Boston, MA $68,000.00 - $93,000.00 2 weeks ago Sr. Director Clinical Operations/Program Lead 2074235
Director of Operational Excellence - Foundry - Methuen, MA
Director of Project and Integration Management
Boston, MA $186,900 - $283,800 2 weeks ago Director, Product Development and Market Research
Director, Thought Leader Liaison Operations Excellence
Springfield, Massachusetts Metropolitan Area 5 days ago Director, Launch Program and Marketing Operations Lead, US Oncology
We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr
Mantell Associates is partnered with an innovative Cell & Gene Therapy organisation, who is seeking an experienced Senior Director of Program Management to lead cross-functional program teams in the development of advanced cell and/or gene therapy programs. The successful candidate will be responsible for driving strategic planning, execution, and delivery of complex projects across research, CMC, clinical, regulatory, and commercial functions. This is a high-impact role requiring leadership, strategic insight, and deep understanding of the biotech product development lifecycle. Senior Director of Program Management - Responsibilities: Lead cross-functional program teams including R&D, CMC, regulatory, clinical, commercial, and business development Develop and maintain comprehensive program plans, timelines, budgets, and risk management strategies Act as the primary point of contact for program-level communication and updates to executive leadership and stakeholders Ensure alignment with corporate strategy, milestones, and financial targets Coordinate with CMC, clinical operations, and regulatory affairs to drive IND/CTA submissions, clinical trials, and BLA/MAA readiness Manage external partnerships including CROs, CDMOs, academic collaborators, and licensing partners Drive decision-making through well-prepared governance presentations and scenario planning Anticipate and mitigate program risks and interdependencies Maintain program documentation and ensure compliance with internal governance and regulatory expectations Senior Director of Program Management - Requirements: Advanced degree in life sciences (PhD, PharmD, MD, or MS); MBA is a plus 10+ years of experience in biotech/pharmaceutical industry, including 5+ years of program management experience Deep expertise in cell and/or gene therapy, including understanding of vector manufacturing, regulatory landscape, and clinical development nuances Experience with rare diseases, oncology, or immunotherapy indications preferred Previous success in global development programs, including FDA and EMA interactions preferred PMP certification or formal project management training preferred Proven track record in leading cross-functional drug development teams from preclinical through clinical and ideally into commercialization Strong leadership, interpersonal, and influencing skills across matrixed organizations Excellent communication, presentation, and organizational skills Experience with tools like MS Project, Smartsheet, or other project planning software Mantell Associates is a specialist Pharmaceutical and Life Science headhunting firm. For more information on this opportunity, contact us at +44 (0)20 3854 7700. Seniority level
Seniority level Director Employment type
Employment type Full-time Job function
Job function Management, Project Management, and Research Industries Biotechnology Research, Pharmaceutical Manufacturing, and Medical Equipment Manufacturing Referrals increase your chances of interviewing at Mantell Associates by 2x Sign in to set job alerts for “Director Program Management” roles.
Associate Director/Director, Project Management
Vice President Director, Project Management
Boston, MA $119,510 - $179,850 2 weeks ago Senior Director, Enterprise Projects and Initiatives Center
Boston, MA $151,500.00 - $222,200.00 1 day ago Director, Project Management & R&D Operations
Director, Early Global Program Team Leader
Cambridge, MA $130,000.00 - $150,000.00 1 week ago Boston, MA $90,000.00 - $100,000.00 6 days ago Haverhill, MA $95,000.00 - $106,000.00 2 weeks ago Boston, MA $175,000.00 - $185,000.00 2 weeks ago Boston, MA $175,000.00 - $190,000.00 3 weeks ago Director of Operations - Medical Device Manufacturing
Site Director – (PACE Center) – Great Opportunity Lowell, MA
Boston, MA $68,000.00 - $93,000.00 2 weeks ago Sr. Director Clinical Operations/Program Lead 2074235
Director of Operational Excellence - Foundry - Methuen, MA
Director of Project and Integration Management
Boston, MA $186,900 - $283,800 2 weeks ago Director, Product Development and Market Research
Director, Thought Leader Liaison Operations Excellence
Springfield, Massachusetts Metropolitan Area 5 days ago Director, Launch Program and Marketing Operations Lead, US Oncology
We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr