Jnana Therapeutics
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Senior Research Associate, In Vivo
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About Us Jnana Therapeutics, a wholly owned subsidiary of Otsuka Pharmaceutical, is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class oral therapies to treat a wide range of diseases, including rare diseases and immune-mediated diseases. Jnana’s lead program, JNT-517, which targets an allosteric site on the phenylalanine transporter SLC6A19, is a potential first-in-class oral approach for the treatment of PKU, a rare genetic metabolic disease. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, and a highly experienced management team. For more information, please visit www.jnanatx.com and follow us on Twitter/X and LinkedIn. At Jnana, you\'ll join a diverse, passionate team dedicated to advancing therapies for challenging diseases. Our collaborative, purpose-driven culture fosters innovation, urgency, and belonging—making Jnana a great place to work Role Overview
Jnana Therapeutics is seeking a Senior Research Associate to join our In Vivo Biology team. The ideal candidate will have strong scientific drive and passion for innovation in a team-focused environment. This role will conduct in vivo PK/PD and efficacy models to support pharmacology and drug discovery efforts. Responsibilities
Implement acute PK/PD models to screen novel compounds for autoimmune targets. Ex-vivo assessment of study samples using MSD, ELISA, and multi-color flow cytometric analysis. Perform independent data analysis and interpretation to support outlining of next steps and recommendations on research approaches. Clearly document and communicate research outcomes to colleagues at team-level and company-level science meetings. Occasional weekend monitoring/dosing of studies. Desired Qualifications & Past Experiences
Bachelor’s degree in Pharmacology, Biology, or other relevant area with 3+ years of industry experience. Must be highly competent in IV, PO, SC and IP dosing of mice, and in-life and terminal blood collection. Experience running PK/PD models. Experience running mouse models of autoimmune disease is a plus. Many different techniques will be used, and training will be provided, but a desire to quickly gain independence is important. Demonstrate strong communication skills and attention to detail. Must be a scientifically motivated self-starter, able to work effectively in a fast-paced team environment and have a high level of independence for planning and executing project requirements in a timely manner. Organization & Roles
Seniority level : Associate Employment type : Full-time Job function : Research Industries : Biotechnology and Pharmaceutical Manufacturing Referrals increase your chances of interviewing at Jnana Therapeutics by 2x Get notified about new Senior Researcher jobs in
Boston, MA .
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Senior Research Associate, In Vivo
role at
Jnana Therapeutics Direct message the job poster from Jnana Therapeutics About Us
About Us Jnana Therapeutics, a wholly owned subsidiary of Otsuka Pharmaceutical, is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class oral therapies to treat a wide range of diseases, including rare diseases and immune-mediated diseases. Jnana’s lead program, JNT-517, which targets an allosteric site on the phenylalanine transporter SLC6A19, is a potential first-in-class oral approach for the treatment of PKU, a rare genetic metabolic disease. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, and a highly experienced management team. For more information, please visit www.jnanatx.com and follow us on Twitter/X and LinkedIn. At Jnana, you\'ll join a diverse, passionate team dedicated to advancing therapies for challenging diseases. Our collaborative, purpose-driven culture fosters innovation, urgency, and belonging—making Jnana a great place to work Role Overview
Jnana Therapeutics is seeking a Senior Research Associate to join our In Vivo Biology team. The ideal candidate will have strong scientific drive and passion for innovation in a team-focused environment. This role will conduct in vivo PK/PD and efficacy models to support pharmacology and drug discovery efforts. Responsibilities
Implement acute PK/PD models to screen novel compounds for autoimmune targets. Ex-vivo assessment of study samples using MSD, ELISA, and multi-color flow cytometric analysis. Perform independent data analysis and interpretation to support outlining of next steps and recommendations on research approaches. Clearly document and communicate research outcomes to colleagues at team-level and company-level science meetings. Occasional weekend monitoring/dosing of studies. Desired Qualifications & Past Experiences
Bachelor’s degree in Pharmacology, Biology, or other relevant area with 3+ years of industry experience. Must be highly competent in IV, PO, SC and IP dosing of mice, and in-life and terminal blood collection. Experience running PK/PD models. Experience running mouse models of autoimmune disease is a plus. Many different techniques will be used, and training will be provided, but a desire to quickly gain independence is important. Demonstrate strong communication skills and attention to detail. Must be a scientifically motivated self-starter, able to work effectively in a fast-paced team environment and have a high level of independence for planning and executing project requirements in a timely manner. Organization & Roles
Seniority level : Associate Employment type : Full-time Job function : Research Industries : Biotechnology and Pharmaceutical Manufacturing Referrals increase your chances of interviewing at Jnana Therapeutics by 2x Get notified about new Senior Researcher jobs in
Boston, MA .
#J-18808-Ljbffr