Johnson & Johnson
Principal Scientist, Viral Vectors (Cell and Genetic Medicines Discovery)
Johnson & Johnson, Cambridge, Massachusetts, us, 02140
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.
Job Function:
Discovery & Pre-Clinical/Clinical Development Job Sub Function:
Biological Research Job Category:
Scientific/Technology All Job Posting Locations:
Cambridge, Massachusetts, United States of America Job Description: About Innovative Medicine. Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. We are searching for the best talent for a
Principal Scientist, Viral Vectors
(Cell and Genetic Medicines Discovery)
to be located in Cambridge, MA. Purpose: We are seeking a highly motivated and experienced scientist to join our CAR-T cell therapy discovery efforts as a Principal Scientist. In this role, you will play a key part in advancing our research initiatives by leveraging your expertise in viral vectors and molecular biology. You will be responsible for: Utilize your extensive knowledge in vector engineering, virology, and molecular biology to drive groundbreaking research in our cell therapy platform and pipeline development. Design, develop, and implement novel methodologies for vector targeting, packaging, and analytical characterization, including assays for vector quantification, potency, and purity. Lead efforts in troubleshooting and refining viral vector quantification techniques such as PCR-based assays, flow cytometry, and vector copy number (VCN) analysis, ensuring robust and reproducible data. Drive continuous improvement of vector production platforms, including titers, purity, and scalability, to enhance overall process efficiency. Maintain expertise and provide innovative solutions to complex research challenges. Initiate and foster collaborative projects with internal cross-functional teams, external partners, and academic institutions to accelerate innovation and knowledge sharing. Present complex data insights to diverse audiences, including research teams and senior leadership, to inform strategic decision-making and project direction. Deliver high-quality results within established timelines, demonstrating ownership and accountability for scientific milestones. Ensure compliance with Good Laboratory Practices (GLP) and Environmental Health and Safety (EHS) protocols. Qualifications: Ph.D. in a relevant field; OR a Master's or Bachelor’s degree with 6-8 years of extensive experience. Extensive hands-on expertise in enveloped viruses, viral vector engineering, production, and characterization; lentiviral vectors preferred. Proven track record in exploratory science with a strong bench science background and willingness to perform experimental work. Deep knowledge of molecular and cellular biology techniques, cell culture, flow cytometry, and high-throughput workflows. Demonstrated ability to develop innovative solutions, troubleshoot complex problems, and optimize processes. Highly organized, detail-oriented, with excellent multitasking skills and the ability to operate independently. Strong collaborative skills and experience working effectively within multidisciplinary teams. Excellent scientific communication skills, including technical writing and presentation abilities tailored for diverse audiences. Commitment to maintaining accurate, detailed records and ensuring reproducibility of experiments. Up to 5-10% travel is required. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. The anticipated base pay range for this position is $115,000 to $197,800.
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Discovery & Pre-Clinical/Clinical Development Job Sub Function:
Biological Research Job Category:
Scientific/Technology All Job Posting Locations:
Cambridge, Massachusetts, United States of America Job Description: About Innovative Medicine. Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. We are searching for the best talent for a
Principal Scientist, Viral Vectors
(Cell and Genetic Medicines Discovery)
to be located in Cambridge, MA. Purpose: We are seeking a highly motivated and experienced scientist to join our CAR-T cell therapy discovery efforts as a Principal Scientist. In this role, you will play a key part in advancing our research initiatives by leveraging your expertise in viral vectors and molecular biology. You will be responsible for: Utilize your extensive knowledge in vector engineering, virology, and molecular biology to drive groundbreaking research in our cell therapy platform and pipeline development. Design, develop, and implement novel methodologies for vector targeting, packaging, and analytical characterization, including assays for vector quantification, potency, and purity. Lead efforts in troubleshooting and refining viral vector quantification techniques such as PCR-based assays, flow cytometry, and vector copy number (VCN) analysis, ensuring robust and reproducible data. Drive continuous improvement of vector production platforms, including titers, purity, and scalability, to enhance overall process efficiency. Maintain expertise and provide innovative solutions to complex research challenges. Initiate and foster collaborative projects with internal cross-functional teams, external partners, and academic institutions to accelerate innovation and knowledge sharing. Present complex data insights to diverse audiences, including research teams and senior leadership, to inform strategic decision-making and project direction. Deliver high-quality results within established timelines, demonstrating ownership and accountability for scientific milestones. Ensure compliance with Good Laboratory Practices (GLP) and Environmental Health and Safety (EHS) protocols. Qualifications: Ph.D. in a relevant field; OR a Master's or Bachelor’s degree with 6-8 years of extensive experience. Extensive hands-on expertise in enveloped viruses, viral vector engineering, production, and characterization; lentiviral vectors preferred. Proven track record in exploratory science with a strong bench science background and willingness to perform experimental work. Deep knowledge of molecular and cellular biology techniques, cell culture, flow cytometry, and high-throughput workflows. Demonstrated ability to develop innovative solutions, troubleshoot complex problems, and optimize processes. Highly organized, detail-oriented, with excellent multitasking skills and the ability to operate independently. Strong collaborative skills and experience working effectively within multidisciplinary teams. Excellent scientific communication skills, including technical writing and presentation abilities tailored for diverse audiences. Commitment to maintaining accurate, detailed records and ensuring reproducibility of experiments. Up to 5-10% travel is required. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. The anticipated base pay range for this position is $115,000 to $197,800.
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