UT Southwestern Medical Center
Research Scientist, Osteosarcoma, Levi Lab
UT Southwestern Medical Center, Dallas, Texas, United States, 75215
Overview
Research Scientist, Osteosarcoma, Levi Lab The Levi laboratory in the Division of Burn, Trauma, Acute and Critical Care Surgery, Department of Surgery at UT Southwestern invites applications for a Research Scientist with an Osteosarcoma focus. The Levi lab’s mission is to improve the lives of people living with skin and musculoskeletal injuries and diseases through rigorous science and compassion. Current projects explore molecular biology behind tissue fibrosis and the repair and regeneration processes in tendon, muscle, and bone. The lab uses multiomics approaches, transgenic animal models, and bioinformatics to understand cell–cell interactions within the stem cell niche and how signaling may guide future therapeutic strategies to promote faithful tissue repair. The position is for a candidate who will join ongoing bench and animal work focused on tendon injury/fibrosis, muscle injury/fibrosis, or bone/tendon/muscle regeneration, and is willing to commit to at least two years. Responsibilities
Plan, coordinate, direct, and participate in bench and animal experiments related to the lab’s projects. Perform routine molecular bench work and work with animal models (handling, injections, surgeries, sample collection). Downstream processing including histology, immunofluorescent staining, confocal imaging, flow cytometry, cell culture, and single-cell and bulk RNA sequencing, under supervision of the PI. Conduct and analyze experiments to investigate molecular mechanisms underlying tissue repair and regeneration. Develop and execute standard operating procedures for experimental protocols. Review, analyze, and interpret research data; revise techniques as indicated by data. Prepare research findings for publication and presentation at meetings; contribute to grant writing and fundraising efforts as appropriate. Collaborate with interdisciplinary teams to apply molecular biology expertise to research projects and initiatives. Assist in training and supervising junior laboratory personnel. Qualifications
PhD with major coursework in the field of assignment or Master’s or Bachelor’s degree with major coursework in the field of assignment, plus relevant research experience. Experience in molecular biology techniques (e.g., PCR, qPCR, Western blotting, RNA/DNA extraction, cloning, CRISPR/Cas9, next-generation sequencing) and in an academic or translational research setting. Experience with animal handling, genotyping, surgery, and breeding. Experience with single-cell transcriptomics, histology, confocal microscopy, flow cytometry, and mass spectrometry is preferred. Strong written and oral communication and organizational skills; ability to analyze data with bioinformatics tools and statistics. Ability to stay current with advances in molecular biology and contribute to new methodologies. Benefits
UT Southwestern offers a competitive benefits package to eligible employees, including healthcare, PTO and holidays, retirement programs, parental leave, wellness programs, tuition reimbursement, public service loan forgiveness eligibility, and other employee benefits. Security and EEO
Security:
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. EEO:
UT Southwestern Medical Center is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, national origin, sex, sexual orientation, gender identity or expression, age, disability, genetic information, citizenship status, or veteran status. Location : Texas-Dallas, 5323 Harry Hines Blvd;
Schedule : Full-time;
Shift : Day Job;
Job Type : Standard;
Job Posting : Jul 10, 2025. For context on the posting, this description reflects current responsibilities and qualifications for the Levi Lab Research Scientist position focused on osteosarcoma, within UT Southwestern.
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Research Scientist, Osteosarcoma, Levi Lab The Levi laboratory in the Division of Burn, Trauma, Acute and Critical Care Surgery, Department of Surgery at UT Southwestern invites applications for a Research Scientist with an Osteosarcoma focus. The Levi lab’s mission is to improve the lives of people living with skin and musculoskeletal injuries and diseases through rigorous science and compassion. Current projects explore molecular biology behind tissue fibrosis and the repair and regeneration processes in tendon, muscle, and bone. The lab uses multiomics approaches, transgenic animal models, and bioinformatics to understand cell–cell interactions within the stem cell niche and how signaling may guide future therapeutic strategies to promote faithful tissue repair. The position is for a candidate who will join ongoing bench and animal work focused on tendon injury/fibrosis, muscle injury/fibrosis, or bone/tendon/muscle regeneration, and is willing to commit to at least two years. Responsibilities
Plan, coordinate, direct, and participate in bench and animal experiments related to the lab’s projects. Perform routine molecular bench work and work with animal models (handling, injections, surgeries, sample collection). Downstream processing including histology, immunofluorescent staining, confocal imaging, flow cytometry, cell culture, and single-cell and bulk RNA sequencing, under supervision of the PI. Conduct and analyze experiments to investigate molecular mechanisms underlying tissue repair and regeneration. Develop and execute standard operating procedures for experimental protocols. Review, analyze, and interpret research data; revise techniques as indicated by data. Prepare research findings for publication and presentation at meetings; contribute to grant writing and fundraising efforts as appropriate. Collaborate with interdisciplinary teams to apply molecular biology expertise to research projects and initiatives. Assist in training and supervising junior laboratory personnel. Qualifications
PhD with major coursework in the field of assignment or Master’s or Bachelor’s degree with major coursework in the field of assignment, plus relevant research experience. Experience in molecular biology techniques (e.g., PCR, qPCR, Western blotting, RNA/DNA extraction, cloning, CRISPR/Cas9, next-generation sequencing) and in an academic or translational research setting. Experience with animal handling, genotyping, surgery, and breeding. Experience with single-cell transcriptomics, histology, confocal microscopy, flow cytometry, and mass spectrometry is preferred. Strong written and oral communication and organizational skills; ability to analyze data with bioinformatics tools and statistics. Ability to stay current with advances in molecular biology and contribute to new methodologies. Benefits
UT Southwestern offers a competitive benefits package to eligible employees, including healthcare, PTO and holidays, retirement programs, parental leave, wellness programs, tuition reimbursement, public service loan forgiveness eligibility, and other employee benefits. Security and EEO
Security:
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. EEO:
UT Southwestern Medical Center is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, national origin, sex, sexual orientation, gender identity or expression, age, disability, genetic information, citizenship status, or veteran status. Location : Texas-Dallas, 5323 Harry Hines Blvd;
Schedule : Full-time;
Shift : Day Job;
Job Type : Standard;
Job Posting : Jul 10, 2025. For context on the posting, this description reflects current responsibilities and qualifications for the Levi Lab Research Scientist position focused on osteosarcoma, within UT Southwestern.
#J-18808-Ljbffr