Genentech
Postdoctoral Fellow, Proteomics and Neuroscience, Ori/Bingol Lab
Genentech, San Francisco, California, United States, 94199
Overview
The Proteomics and Genomics Technologies department develops and employs innovative proteomic and genomic technologies to advance basic research programs as well as support a multitude of modalities across Genentech’s therapeutic pipeline. The Neuroscience department aims to discover novel pathogenic mechanisms of neurodegeneration with the ultimate aim of targeting them to alleviate disease. A position is available for a postdoctoral fellow with expertise in molecular and cellular neuroscience, iPSC-derived models, and omics data to join the Departments of Proteomics and Genomics Technologies and Neuroscience at Genentech, Inc. We have in-house cutting-edge technologies including proteomics, lipidomics, NGS, CRISPR screens, in vitro and in vivo models, and AI/ML-supported computational biology. The Opportunity
Active areas of research include mechanistic investigation of the impact of disease on key cellular organelles including mitochondria and lysosomes, and high-throughput proteome profiling of perturbations in iPSC-derived brain cell types. The project will entail a combination of unbiased discovery and hypothesis-driven research to derive causal relationships between pathways contributing to neurodegeneration. You will be responsible for the generation of large-scale datasets, derivation of causal models and follow up mechanistic investigations of novel findings. You will work at the interface between disciplines and leverage expertise from different research areas including proteomics, functional genomics, computational biology and neuroscience. Who You Are
Candidates must have a Ph.D. in biology, biophysics, biochemistry or a related discipline. Team player with a fearless attitude to tackle long standing, difficult problems in neuroscience. Strong background in culturing and manipulating iPSC-derived models, organelle biology, CRISPR screens or neuroscience as evidenced by a first author paper published or accepted in peer-reviewed journals. Preferred Qualifications
Strong computational skills to derive mechanistic insights would be advantageous. Highly motivated and capable of independent work in a collaborative and multidisciplinary environment. Previous experience with proteomics is not required. Additional Information
To learn more about the Ori Lab, please see the following link: https://www.gene.com/scientists/our-scientists/alessandro-ori To learn more about the Bingol Lab, please see the following link: https://www.gene.com/scientists/our-scientists/baris-bingol The expected salary range for this position based on the primary location of South San Francisco, California is $98,000 and $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed below. Benefits: Relocation benefits are available for this position. Postdoc Program
Elevate your research career to new heights with Genentech’s Postdoctoral Program. Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. The program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company’s policy prohibits unlawful discrimination, including but not limited to discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form: Accommodations for Applicants.
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The Proteomics and Genomics Technologies department develops and employs innovative proteomic and genomic technologies to advance basic research programs as well as support a multitude of modalities across Genentech’s therapeutic pipeline. The Neuroscience department aims to discover novel pathogenic mechanisms of neurodegeneration with the ultimate aim of targeting them to alleviate disease. A position is available for a postdoctoral fellow with expertise in molecular and cellular neuroscience, iPSC-derived models, and omics data to join the Departments of Proteomics and Genomics Technologies and Neuroscience at Genentech, Inc. We have in-house cutting-edge technologies including proteomics, lipidomics, NGS, CRISPR screens, in vitro and in vivo models, and AI/ML-supported computational biology. The Opportunity
Active areas of research include mechanistic investigation of the impact of disease on key cellular organelles including mitochondria and lysosomes, and high-throughput proteome profiling of perturbations in iPSC-derived brain cell types. The project will entail a combination of unbiased discovery and hypothesis-driven research to derive causal relationships between pathways contributing to neurodegeneration. You will be responsible for the generation of large-scale datasets, derivation of causal models and follow up mechanistic investigations of novel findings. You will work at the interface between disciplines and leverage expertise from different research areas including proteomics, functional genomics, computational biology and neuroscience. Who You Are
Candidates must have a Ph.D. in biology, biophysics, biochemistry or a related discipline. Team player with a fearless attitude to tackle long standing, difficult problems in neuroscience. Strong background in culturing and manipulating iPSC-derived models, organelle biology, CRISPR screens or neuroscience as evidenced by a first author paper published or accepted in peer-reviewed journals. Preferred Qualifications
Strong computational skills to derive mechanistic insights would be advantageous. Highly motivated and capable of independent work in a collaborative and multidisciplinary environment. Previous experience with proteomics is not required. Additional Information
To learn more about the Ori Lab, please see the following link: https://www.gene.com/scientists/our-scientists/alessandro-ori To learn more about the Bingol Lab, please see the following link: https://www.gene.com/scientists/our-scientists/baris-bingol The expected salary range for this position based on the primary location of South San Francisco, California is $98,000 and $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed below. Benefits: Relocation benefits are available for this position. Postdoc Program
Elevate your research career to new heights with Genentech’s Postdoctoral Program. Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. The program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company’s policy prohibits unlawful discrimination, including but not limited to discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form: Accommodations for Applicants.
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