Aragen Life Sciences
Research Associate/Sr Research Associate: In vivo Preclinical Research
Aragen Life Sciences, Morgan Hill, California, us, 95038
Overview
Aragen Bioscience is a leading contract research organization focused on accelerating product development. Aragen’s offerings include an entire portfolio of preclinical research services including cell-based assays and in vivo models of disease. We offer clients high quality service and superior R&D partnerships.
Position Overview: Research Associates / Senior Research Associates will be responsible for primarily conducting in vivo experiments to evaluate efficacy of client test compounds across various rodent models with a secondary role in supporting in vitro/ex vivo lab work and aiding in staff distributed duties to support daily lab and vivarium operations. A successful candidate will have hands-on experience with in vivo animal studies and working knowledge of in vitro laboratory techniques to support in vivo studies, such as tissue culture, RNA/DNA processing, and ELISA/Western Blot. Candidates will work closely with multidisciplinary teams to support various client and internal projects.
Key Responsibilities
Assist in the design and execution of in vivo rodent studies across various therapeutic areas with duties including animal weighing, dose administration (e.g. subQ, IP, PO, IM, retro-orbital, IV), blood and tissue collection, necropsy, oncology and functional readouts.
Perform in vivo imaging and analysis of data in cancer models
Proficient with cell culture techniques using various immortalized cell lines to support oncology studies is desired
General understanding of pharmacokinetics, pharmacodynamics, and drug metabolism
Ability to follow strict instructions on formulation of test compounds for in vivo dosing
Analyze in vivo data independently or under minimal guidance of senior scientists
Contribute to generation of reports for in vivo experiments or other related study presentations with guidance of senior scientists
Work collaboratively with cross-functional teams to support department’s goals and timelines
Aid in lab equipment maintenance and general lab support
Maintain a safe laboratory environment by following standard operating procedures (SOP) and established IACUC protocols
Other related duties as assigned
Required Qualifications
BA/BS or MS in Biology, Immunology, Biomedical Sciences, Microbiology, Virology, Pharmaceutical Sciences, Pharmacology or a related discipline
Two or more years of laboratory experience utilizing techniques or methods required by the position or an equivalent combination of education and experience in an academic lab environment
Recent post graduates with a desire to expand their skill set are encouraged to apply
Must be comfortable working with rodents and animal derived tissues or fluids
Adept at using automated instrumentation for analysis (e.g. IDEXX or HESKA machines)
Openness to learning new methods and skills for shifting research needs based on clients
General understanding of data analysis techniques and use of software (e.g. Microsoft Excel and GraphPad Prism)
Excellent organizational skills with attention to detail and ability to prioritize tasks to meet deadlines
Strong written/verbal communication skills for assisting with writing reports, presentations, and client interactions
Some evening and weekend/holiday hours are required
Preferred Qualifications
Extensive and relevant research experience using rodent models of human disease
Proficiency in a specialized therapeutic area such as fibrosis, virology, autoimmune disorders, immunology, and oncology
Experience with oncology models
Experience with in vitro/ex vivo assay development
Hands-on knowledge of general laboratory techniques, including basic molecular or cellular biology techniques (e.g. RNA/DNA isolation, gel electrophoresis, PCR, RNASeq, bacterial culture and transformation, Western Blot, ELISA, mammalian cell culture, etc.)
Working familiarity with cell based immunology techniques such as MSD/ELISA and FACS
Understanding of preclinical drug development and regulatory process
Prior experience handling small molecules/biologics for PK/PD studies
Additional Information No Sponsorship will be offered. Seeking local candidates.
Why Join Us? Aragen Bioscience provides a stimulating work environment in which talented employees expand their technical skills and scientific knowledge and contribute directly to the ongoing success of the organization. The Company is located in Morgan Hill, California, at the south end of the Silicon Valley. We offer excellent salary and benefits. Aragen is an equal opportunity employer.
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Position Overview: Research Associates / Senior Research Associates will be responsible for primarily conducting in vivo experiments to evaluate efficacy of client test compounds across various rodent models with a secondary role in supporting in vitro/ex vivo lab work and aiding in staff distributed duties to support daily lab and vivarium operations. A successful candidate will have hands-on experience with in vivo animal studies and working knowledge of in vitro laboratory techniques to support in vivo studies, such as tissue culture, RNA/DNA processing, and ELISA/Western Blot. Candidates will work closely with multidisciplinary teams to support various client and internal projects.
Key Responsibilities
Assist in the design and execution of in vivo rodent studies across various therapeutic areas with duties including animal weighing, dose administration (e.g. subQ, IP, PO, IM, retro-orbital, IV), blood and tissue collection, necropsy, oncology and functional readouts.
Perform in vivo imaging and analysis of data in cancer models
Proficient with cell culture techniques using various immortalized cell lines to support oncology studies is desired
General understanding of pharmacokinetics, pharmacodynamics, and drug metabolism
Ability to follow strict instructions on formulation of test compounds for in vivo dosing
Analyze in vivo data independently or under minimal guidance of senior scientists
Contribute to generation of reports for in vivo experiments or other related study presentations with guidance of senior scientists
Work collaboratively with cross-functional teams to support department’s goals and timelines
Aid in lab equipment maintenance and general lab support
Maintain a safe laboratory environment by following standard operating procedures (SOP) and established IACUC protocols
Other related duties as assigned
Required Qualifications
BA/BS or MS in Biology, Immunology, Biomedical Sciences, Microbiology, Virology, Pharmaceutical Sciences, Pharmacology or a related discipline
Two or more years of laboratory experience utilizing techniques or methods required by the position or an equivalent combination of education and experience in an academic lab environment
Recent post graduates with a desire to expand their skill set are encouraged to apply
Must be comfortable working with rodents and animal derived tissues or fluids
Adept at using automated instrumentation for analysis (e.g. IDEXX or HESKA machines)
Openness to learning new methods and skills for shifting research needs based on clients
General understanding of data analysis techniques and use of software (e.g. Microsoft Excel and GraphPad Prism)
Excellent organizational skills with attention to detail and ability to prioritize tasks to meet deadlines
Strong written/verbal communication skills for assisting with writing reports, presentations, and client interactions
Some evening and weekend/holiday hours are required
Preferred Qualifications
Extensive and relevant research experience using rodent models of human disease
Proficiency in a specialized therapeutic area such as fibrosis, virology, autoimmune disorders, immunology, and oncology
Experience with oncology models
Experience with in vitro/ex vivo assay development
Hands-on knowledge of general laboratory techniques, including basic molecular or cellular biology techniques (e.g. RNA/DNA isolation, gel electrophoresis, PCR, RNASeq, bacterial culture and transformation, Western Blot, ELISA, mammalian cell culture, etc.)
Working familiarity with cell based immunology techniques such as MSD/ELISA and FACS
Understanding of preclinical drug development and regulatory process
Prior experience handling small molecules/biologics for PK/PD studies
Additional Information No Sponsorship will be offered. Seeking local candidates.
Why Join Us? Aragen Bioscience provides a stimulating work environment in which talented employees expand their technical skills and scientific knowledge and contribute directly to the ongoing success of the organization. The Company is located in Morgan Hill, California, at the south end of the Silicon Valley. We offer excellent salary and benefits. Aragen is an equal opportunity employer.
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