BioSpace
Scientist, Mass Spectrometry and Critical Reagents
BioSpace, Norwood, Massachusetts, us, 02062
Overview
Scientist, Mass Spectrometry and Critical Reagents. The Scientist will be responsible to support the protein quantification and proteomics analysis using Mass spectrometry for PK and PD studies, ensuring the timely and efficient management of critical reagents used in the development, validation, and execution of bioanalytical and molecular assays to support clinical assays at Moderna. The successful candidate will work closely with cross-functional teams for protein analysis, qualify critical reagents, as well as establish and maintain robust systems for their monitoring, tracking, and storage. This is an in-person laboratory-based position located in Norwood, MA. Here’s What You’ll Do
Support LC-MS based protein quantification/proteomics assay development, validation and sample analysis under regulatory compliance. A solid background in modern analytical techniques used in the analysis of mRNA-based therapeutic products is essential. Maintain a robust system for the monitoring, tracking, and storage of critical reagents to ensure their availability and quality. Support reagent characterization to generate CoA documentation. Knowledge of peptide/proteins, aptamer-antibody based conjugation systems for DNA, RNA, and Protein/antibodies. Maintain a database of Reference standards/reagents, including their specifications, source, usage, and expiration dates. Conduct regular audits of critical reagent inventory and work with cross-functional teams to manage the procurement and disposition of the reagents. Vendor management to ensure the availability and quality of critical reagents. Develop and implement policies, procedures, and training programs to ensure compliance with regulatory requirements and industry best practices. Collaborate with cross-functional teams to develop reagent-specific risk assessments and mitigation strategies. Monitor industry trends and advancements in critical reagent management and implement best practices to improve efficiency and effectiveness. Basic Qualifications
Ph.D. in a scientific field, such as chemistry, biochemistry, or biology with 3+ years of experience in Bioanalytical Sciences/regulated bioanalysis. M.S. with at least 7 years of bioanalytical experience will also be considered. Strong knowledge of critical reagents management as well as current industry best practices and regulatory requirements. Deep understanding of Proteomics/Protein mass spectrometry for PK and biomarker analysis. Demonstrated ability to work collaboratively with cross-functional teams to achieve shared goals. Excellent organizational, analytical, and problem-solving skills. Proven ability to manage multiple projects simultaneously and prioritize tasks in a fast-paced environment. Preferred Qualifications
Experience with the Biophysical Characterization of Biologics (LCMS, SDS-PAGE, cIEF, SPR, BLI, SEC-HPLC, SEC-MALS, UV-VIS). Experience working in a GLP environment (ELN/LIMS/automation). Experience with HRMS and software for protein analysis/characterization. About Moderna
Since our founding in 2010, Moderna aspires to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people drive scientific progress and culture. Moderna is recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, visit modernatx.com/careers to learn more about our current opportunities. Our Working Model
Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 in-office work model. This structure helps foster a culture rich in innovation, teamwork, and direct mentorship. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications and you would be excited to contribute to our mission, please apply. Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process should contact the Accommodations team at leavesandaccommodations@modernatx.com. Export Control Notice
This position may involve access to technology or data subject to U.S. export control laws. Employment is contingent upon ability to access export-controlled information in accordance with U.S. law. Only U.S. persons are eligible for this role; Moderna cannot sponsor non-U.S. persons to apply for an export control license.
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Scientist, Mass Spectrometry and Critical Reagents. The Scientist will be responsible to support the protein quantification and proteomics analysis using Mass spectrometry for PK and PD studies, ensuring the timely and efficient management of critical reagents used in the development, validation, and execution of bioanalytical and molecular assays to support clinical assays at Moderna. The successful candidate will work closely with cross-functional teams for protein analysis, qualify critical reagents, as well as establish and maintain robust systems for their monitoring, tracking, and storage. This is an in-person laboratory-based position located in Norwood, MA. Here’s What You’ll Do
Support LC-MS based protein quantification/proteomics assay development, validation and sample analysis under regulatory compliance. A solid background in modern analytical techniques used in the analysis of mRNA-based therapeutic products is essential. Maintain a robust system for the monitoring, tracking, and storage of critical reagents to ensure their availability and quality. Support reagent characterization to generate CoA documentation. Knowledge of peptide/proteins, aptamer-antibody based conjugation systems for DNA, RNA, and Protein/antibodies. Maintain a database of Reference standards/reagents, including their specifications, source, usage, and expiration dates. Conduct regular audits of critical reagent inventory and work with cross-functional teams to manage the procurement and disposition of the reagents. Vendor management to ensure the availability and quality of critical reagents. Develop and implement policies, procedures, and training programs to ensure compliance with regulatory requirements and industry best practices. Collaborate with cross-functional teams to develop reagent-specific risk assessments and mitigation strategies. Monitor industry trends and advancements in critical reagent management and implement best practices to improve efficiency and effectiveness. Basic Qualifications
Ph.D. in a scientific field, such as chemistry, biochemistry, or biology with 3+ years of experience in Bioanalytical Sciences/regulated bioanalysis. M.S. with at least 7 years of bioanalytical experience will also be considered. Strong knowledge of critical reagents management as well as current industry best practices and regulatory requirements. Deep understanding of Proteomics/Protein mass spectrometry for PK and biomarker analysis. Demonstrated ability to work collaboratively with cross-functional teams to achieve shared goals. Excellent organizational, analytical, and problem-solving skills. Proven ability to manage multiple projects simultaneously and prioritize tasks in a fast-paced environment. Preferred Qualifications
Experience with the Biophysical Characterization of Biologics (LCMS, SDS-PAGE, cIEF, SPR, BLI, SEC-HPLC, SEC-MALS, UV-VIS). Experience working in a GLP environment (ELN/LIMS/automation). Experience with HRMS and software for protein analysis/characterization. About Moderna
Since our founding in 2010, Moderna aspires to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people drive scientific progress and culture. Moderna is recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, visit modernatx.com/careers to learn more about our current opportunities. Our Working Model
Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 in-office work model. This structure helps foster a culture rich in innovation, teamwork, and direct mentorship. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications and you would be excited to contribute to our mission, please apply. Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process should contact the Accommodations team at leavesandaccommodations@modernatx.com. Export Control Notice
This position may involve access to technology or data subject to U.S. export control laws. Employment is contingent upon ability to access export-controlled information in accordance with U.S. law. Only U.S. persons are eligible for this role; Moderna cannot sponsor non-U.S. persons to apply for an export control license.
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