Champions Oncology, Inc.
Research Associate I, Radiopharmacology
Champions Oncology, Inc., Rockville, Maryland, us, 20849
Research Associate I, Radiopharmacology
Champions Oncology, Inc. – Rockville, MD
Primary Objectives Perform cross‑functional laboratory assays with focus on synthesis and purification of radiolabeled compounds and their characterization. Assist in development and execution of novel assays, collecting and processing data.
Duties and Responsibilities
Perform bioconjugation reactions using bifunctional chelating agents and/or fluorescent labels
Perform synthesis and purification of radiolabeled compounds (e.g., PET/SPECT tracers, radiotherapeutics) using isotopes such as Lu-177, Ac-225, Pb-212, Cu-46 and Zr-89
Perform in vitro assays (e.g., receptor binding, internalization, stability studies) using radiolabeled compounds in cell‑based systems
Operate and maintain radiochemistry equipment including hot cells, dose calibrators, and automated synthesis modules
Quantify radioactivity using gamma counters, scintillation counters, or autoradiography
Ensure compliance with radiation safety protocols and institutional regulations
Maintain accurate and detailed records in electronic lab notebooks (ELNs)
Collaborate with cross‑functional teams including in‑vivo and ex‑vivo
Contribute to SOPs and assay workflows for conjugation, radiolabeling and in‑vitro characterization assays of radiolabeled compounds
Contribute to data processing and preparation for client presentation
Maintain laboratory and supply inventory
Contribute to group cohesion and teamwork
Other duties may be assigned verbally at any time
Qualifications
Experience working in a laboratory setting
Proficiency with one or more of the following techniques: weighing chemical substances, preparing buffers and chemical solutions, using micropipettes
Demonstrated ability to work effectively and productively in a team‑oriented environment while maintaining a strong sense of integrity and confidentiality
Creative problem‑solving skills and the ability to exercise sound and accurate judgment in making timely decisions
Eager to learn new techniques
Strong planning, organizational, computer, written and verbal communication skills
Demonstrated accountability, initiative, and responsibility for own work
Ability to observe safety and security procedures
Ability to assist with other tasks/duties as needed in a small company environment
Education and Experience
BS or MS degree with 0‑2 years of relevant experience required. Preferred field of study: radiochemistry, biochemistry, chemistry, chemical engineering, biomedical engineering, biology, or related sciences
Experience performing chemistry or biochemistry reactions preferred
Previous experience working with radioactive materials preferred but training will be provided
Physical Demands and Work Environment
Must be able to sit and use hands to finger, handle and feel
Must be able to lift and move packages weighing up to 50 pounds
Must be able to sit for long periods of time using a computer in a typical office environment in a multi‑level facility
Some activities require repetitive motion and reaching, pulling, or pushing
In carrying out the duties of the job there will be occasional exposure to fumes and chemical hazards
Duties performed routinely require exposure to blood and tissue in BSL‑2 environment
We celebrate diversity and are committed to creating an inclusive environment for all employees
#J-18808-Ljbffr
Primary Objectives Perform cross‑functional laboratory assays with focus on synthesis and purification of radiolabeled compounds and their characterization. Assist in development and execution of novel assays, collecting and processing data.
Duties and Responsibilities
Perform bioconjugation reactions using bifunctional chelating agents and/or fluorescent labels
Perform synthesis and purification of radiolabeled compounds (e.g., PET/SPECT tracers, radiotherapeutics) using isotopes such as Lu-177, Ac-225, Pb-212, Cu-46 and Zr-89
Perform in vitro assays (e.g., receptor binding, internalization, stability studies) using radiolabeled compounds in cell‑based systems
Operate and maintain radiochemistry equipment including hot cells, dose calibrators, and automated synthesis modules
Quantify radioactivity using gamma counters, scintillation counters, or autoradiography
Ensure compliance with radiation safety protocols and institutional regulations
Maintain accurate and detailed records in electronic lab notebooks (ELNs)
Collaborate with cross‑functional teams including in‑vivo and ex‑vivo
Contribute to SOPs and assay workflows for conjugation, radiolabeling and in‑vitro characterization assays of radiolabeled compounds
Contribute to data processing and preparation for client presentation
Maintain laboratory and supply inventory
Contribute to group cohesion and teamwork
Other duties may be assigned verbally at any time
Qualifications
Experience working in a laboratory setting
Proficiency with one or more of the following techniques: weighing chemical substances, preparing buffers and chemical solutions, using micropipettes
Demonstrated ability to work effectively and productively in a team‑oriented environment while maintaining a strong sense of integrity and confidentiality
Creative problem‑solving skills and the ability to exercise sound and accurate judgment in making timely decisions
Eager to learn new techniques
Strong planning, organizational, computer, written and verbal communication skills
Demonstrated accountability, initiative, and responsibility for own work
Ability to observe safety and security procedures
Ability to assist with other tasks/duties as needed in a small company environment
Education and Experience
BS or MS degree with 0‑2 years of relevant experience required. Preferred field of study: radiochemistry, biochemistry, chemistry, chemical engineering, biomedical engineering, biology, or related sciences
Experience performing chemistry or biochemistry reactions preferred
Previous experience working with radioactive materials preferred but training will be provided
Physical Demands and Work Environment
Must be able to sit and use hands to finger, handle and feel
Must be able to lift and move packages weighing up to 50 pounds
Must be able to sit for long periods of time using a computer in a typical office environment in a multi‑level facility
Some activities require repetitive motion and reaching, pulling, or pushing
In carrying out the duties of the job there will be occasional exposure to fumes and chemical hazards
Duties performed routinely require exposure to blood and tissue in BSL‑2 environment
We celebrate diversity and are committed to creating an inclusive environment for all employees
#J-18808-Ljbffr