University of Miami
Associate Scientist – Proteomics
University of Miami – Full‑time, Staff, Pay Grade A11
Overview The Sylvester Comprehensive Cancer Center invites applications for an Associate Scientist to join our newly established Proteomic Shared Resources. The role is located onsite at the UHealth campus in Miami, FL and focuses on advanced LC‑MS based quantitative proteomics.
Core Job Summary The Associate Scientist, SOM supports the University’s research goals and objectives by performing laboratory experiments within their area of expertise or assignment. Moreover, the incumbent conducts analytical procedures involving method development, application development, and synthesis.
Core Job Functions
Contributes to basic and applied research activities, including authorship of scientific publications, technical and agency reports, and patent preparations.
Publishes in refereed journals in collaboration with department leadership or independently.
Supervises research employees and non‑exempt staff.
Writes extramural proposals with approval of senior managing staff.
Creates and conducts experiments and analyzes results.
Works with other researchers to use and develop end products.
Provides ready access to all experimental data for faculty researchers, supervisors, and other relevant staff.
Requests or acquires equipment and supplies for assigned project(s).
Applies for grants to continue research and prepares materials for submission to granting agencies and foundations.
Adheres to University and unit‑level policies and procedures and safeguards University assets.
Maintains and operates a modern high‑resolution orbitrap mass spectrometer (Orbitrap Ascend Tribrid LC‑MS).
Manages inventory of lab consumables, including ordering, receiving, and storage of supply stocks.
Prepares protein samples from a wide range of specimens (e.g., cells, tissues, biofluids, and SDS‑Page gels).
Implements both bottom‑up and top‑down proteomic approaches.
Conducts global proteome profiling by data‑dependent (DDA) and data‑independent (DIA) acquisition mass spectrometry and mass bar‑codes; detects post‑translational modifications (e.g., phosphorylation, acetylation).
Performs relative quantification of proteins by label‑free and stable‑isotope labeling strategies (e.g., SILAC, TMT).
Responsible for structural proteomics (e.g., cross‑linking, pull‑down experiments).
Conducts single‑cell proteomics analysis.
Performs intact protein analysis and MW determination.
Uses proteomics software (e.g., Proteome Discoverer, MASCOT) for data analysis.
Operates, maintains, and troubleshoots Orbitrap Ascend Tribrid Mass Spectrometry and other laboratory equipment as needed.
Assesses experimental results and troubleshoots methods and instruments to optimize research protocols.
Collaborates efficiently with technicians, graduate students, post‑docs, PIs, the laboratory director, and colleagues.
Core Qualifications
Education:
Doctorate degree – Philosophy (PhD) required.
Experience:
Minimum 5 years of relevant experience required.
Knowledge, Skills and Abilities:
Learning agility – Ability to learn new procedures, technologies, and protocols, and adapt to changing priorities.
Teamwork – Ability to work collaboratively with others and contribute to a team environment.
Technical proficiency – Skilled in using office software, technology, and relevant computer applications.
Communication – Strong and clear written and verbal communication skills for interacting with colleagues and stakeholders.
Analytical, problem‑solving, and organizational skills.
Excellent written and oral communication skills.
Established track record of publications and demonstrated ability to complete projects.
Capability to learn complex tasks with instruction and to use experience to perform a variety of new techniques.
Education (Department Specific):
Ph.D. in Science or Engineering (Biochemistry, Bioengineering, Biology, Chemistry, or related field).
Knowledge, Skills and Attitudes (Department Specific):
5 years of related experience with mass spectrometry instruments, including 2 years of experience in proteomics mass spectrometry applications.
Hands‑on experience operating and/or maintaining LC‑MS instruments and supporting equipment (auxiliary systems such as chillers, controls, electronics, pumps, vacuum systems).
Strong interest in handling, processing, and analyzing high‑throughput datasets.
Motivation to constantly develop skills and expertise.
Ability to work both independently and as a team member while engaging in the organization of the proteomics core.
Excellent analytical, communication, problem solving, and organizational skills.
Excellent written and oral communication skills.
Established track record of publications and demonstrated ability to complete projects.
Preferences:
Expertise in one or more of the following technical areas: quantitative proteomics, single‑cell proteomic analysis, global proteome profiling.
Previous hands‑on operation of Thermo Tribrid Orbitrap LC‑MS Systems (e.g., Fusion, Eclipse, Ascend).
Benefits Competitive salaries and a comprehensive benefits package, including medical, dental, tuition remission, and more. The University of Miami is an Equal Opportunity Employer; Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.
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Overview The Sylvester Comprehensive Cancer Center invites applications for an Associate Scientist to join our newly established Proteomic Shared Resources. The role is located onsite at the UHealth campus in Miami, FL and focuses on advanced LC‑MS based quantitative proteomics.
Core Job Summary The Associate Scientist, SOM supports the University’s research goals and objectives by performing laboratory experiments within their area of expertise or assignment. Moreover, the incumbent conducts analytical procedures involving method development, application development, and synthesis.
Core Job Functions
Contributes to basic and applied research activities, including authorship of scientific publications, technical and agency reports, and patent preparations.
Publishes in refereed journals in collaboration with department leadership or independently.
Supervises research employees and non‑exempt staff.
Writes extramural proposals with approval of senior managing staff.
Creates and conducts experiments and analyzes results.
Works with other researchers to use and develop end products.
Provides ready access to all experimental data for faculty researchers, supervisors, and other relevant staff.
Requests or acquires equipment and supplies for assigned project(s).
Applies for grants to continue research and prepares materials for submission to granting agencies and foundations.
Adheres to University and unit‑level policies and procedures and safeguards University assets.
Maintains and operates a modern high‑resolution orbitrap mass spectrometer (Orbitrap Ascend Tribrid LC‑MS).
Manages inventory of lab consumables, including ordering, receiving, and storage of supply stocks.
Prepares protein samples from a wide range of specimens (e.g., cells, tissues, biofluids, and SDS‑Page gels).
Implements both bottom‑up and top‑down proteomic approaches.
Conducts global proteome profiling by data‑dependent (DDA) and data‑independent (DIA) acquisition mass spectrometry and mass bar‑codes; detects post‑translational modifications (e.g., phosphorylation, acetylation).
Performs relative quantification of proteins by label‑free and stable‑isotope labeling strategies (e.g., SILAC, TMT).
Responsible for structural proteomics (e.g., cross‑linking, pull‑down experiments).
Conducts single‑cell proteomics analysis.
Performs intact protein analysis and MW determination.
Uses proteomics software (e.g., Proteome Discoverer, MASCOT) for data analysis.
Operates, maintains, and troubleshoots Orbitrap Ascend Tribrid Mass Spectrometry and other laboratory equipment as needed.
Assesses experimental results and troubleshoots methods and instruments to optimize research protocols.
Collaborates efficiently with technicians, graduate students, post‑docs, PIs, the laboratory director, and colleagues.
Core Qualifications
Education:
Doctorate degree – Philosophy (PhD) required.
Experience:
Minimum 5 years of relevant experience required.
Knowledge, Skills and Abilities:
Learning agility – Ability to learn new procedures, technologies, and protocols, and adapt to changing priorities.
Teamwork – Ability to work collaboratively with others and contribute to a team environment.
Technical proficiency – Skilled in using office software, technology, and relevant computer applications.
Communication – Strong and clear written and verbal communication skills for interacting with colleagues and stakeholders.
Analytical, problem‑solving, and organizational skills.
Excellent written and oral communication skills.
Established track record of publications and demonstrated ability to complete projects.
Capability to learn complex tasks with instruction and to use experience to perform a variety of new techniques.
Education (Department Specific):
Ph.D. in Science or Engineering (Biochemistry, Bioengineering, Biology, Chemistry, or related field).
Knowledge, Skills and Attitudes (Department Specific):
5 years of related experience with mass spectrometry instruments, including 2 years of experience in proteomics mass spectrometry applications.
Hands‑on experience operating and/or maintaining LC‑MS instruments and supporting equipment (auxiliary systems such as chillers, controls, electronics, pumps, vacuum systems).
Strong interest in handling, processing, and analyzing high‑throughput datasets.
Motivation to constantly develop skills and expertise.
Ability to work both independently and as a team member while engaging in the organization of the proteomics core.
Excellent analytical, communication, problem solving, and organizational skills.
Excellent written and oral communication skills.
Established track record of publications and demonstrated ability to complete projects.
Preferences:
Expertise in one or more of the following technical areas: quantitative proteomics, single‑cell proteomic analysis, global proteome profiling.
Previous hands‑on operation of Thermo Tribrid Orbitrap LC‑MS Systems (e.g., Fusion, Eclipse, Ascend).
Benefits Competitive salaries and a comprehensive benefits package, including medical, dental, tuition remission, and more. The University of Miami is an Equal Opportunity Employer; Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.
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