US Tech Solutions, Inc.
Scientist II-Bioanalysis
US Tech Solutions, Inc., South San Francisco, California, United States, 94080
Duration: 6 months contract
Not sure what skills you will need for this opportunity Simply read the full description below to get a complete picture of candidate requirements.
Description:
The
Quantitative, Translational ADME Sciences
(QTAS) department is seeking a highly motivated Scientist to join the
Biologics bioanalysis, characterization, and proteomics
group. The main function of this position is to
develop and implement LC/MS (liquid chromatography/mass spectrometry)-based bioanalysis and in vitro characterization assays for biologics
entities. The successful candidate will be experienced in the
development, optimization and implementation and routine LC/MS-based bioanalytical methods
to support in vivo PK, TK, and PK/PD studies as well as in vitro stability characterization of therapeutic proteins, peptides, and oligonucleotides. The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation.
Responsibilities:
Operate and maintain
LC/MS instruments
to generate high-quality experimental data. Perform
affinity purification
of
therapeutic proteins
(including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices. Analyze data
and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks. Facilitate
assay optimization and implementation
to ensure laboratory capacity and data quality. Communicate data interpretation internally and externally.
Skills:
Highly motivated, self-driven and results-oriented with communication and presentation skills; capable of working both as a team player and individual contributor. Prior
industry experience in drug discovery/development
is preferred. In-depth understanding of
PK, TK and PK/PD studies
and corresponding
bioanalytical
assays
as well as in vitro characterization assays is highly desired. Experience on
routine LC/MS-based bioanalysis to support in vivo PK, TK, and PK/PD studies . Hands-on experience with
QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers
highly desired. Hands-on experience with
automated liquid handling
systems highly desired. Hands-on experience with
oligonucleotide analysis
highly desired.
Education and experience:
BS degree in
Chemistry, Pharmacology
or other related fields with 3+ years or MS with 2+ years in a
pharmaceutical industry
setting with a focus on
mass spectrometry,
or
PhD degree .
About US Tech Solutions: US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.
US Tech Solutions is an Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Not sure what skills you will need for this opportunity Simply read the full description below to get a complete picture of candidate requirements.
Description:
The
Quantitative, Translational ADME Sciences
(QTAS) department is seeking a highly motivated Scientist to join the
Biologics bioanalysis, characterization, and proteomics
group. The main function of this position is to
develop and implement LC/MS (liquid chromatography/mass spectrometry)-based bioanalysis and in vitro characterization assays for biologics
entities. The successful candidate will be experienced in the
development, optimization and implementation and routine LC/MS-based bioanalytical methods
to support in vivo PK, TK, and PK/PD studies as well as in vitro stability characterization of therapeutic proteins, peptides, and oligonucleotides. The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation.
Responsibilities:
Operate and maintain
LC/MS instruments
to generate high-quality experimental data. Perform
affinity purification
of
therapeutic proteins
(including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices. Analyze data
and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks. Facilitate
assay optimization and implementation
to ensure laboratory capacity and data quality. Communicate data interpretation internally and externally.
Skills:
Highly motivated, self-driven and results-oriented with communication and presentation skills; capable of working both as a team player and individual contributor. Prior
industry experience in drug discovery/development
is preferred. In-depth understanding of
PK, TK and PK/PD studies
and corresponding
bioanalytical
assays
as well as in vitro characterization assays is highly desired. Experience on
routine LC/MS-based bioanalysis to support in vivo PK, TK, and PK/PD studies . Hands-on experience with
QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers
highly desired. Hands-on experience with
automated liquid handling
systems highly desired. Hands-on experience with
oligonucleotide analysis
highly desired.
Education and experience:
BS degree in
Chemistry, Pharmacology
or other related fields with 3+ years or MS with 2+ years in a
pharmaceutical industry
setting with a focus on
mass spectrometry,
or
PhD degree .
About US Tech Solutions: US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.
US Tech Solutions is an Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.